Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
PLK4ENSG00000142731                                                                                                                                    
PDE6AENSG00000132915                                                                                                                                    
BLKENSG00000136573                                                                                                                                    
PTP4A3ENSG00000184489                                                                                                                                    
RAB9AENSG00000123595                                                                                                                                    
IRAK1ENSG00000184216                                                                                                                                    
GALEENSG00000117308                                                                                                                                    
GLULENSG00000135821                                                                                                                                    
ATP6V1G3ENSG00000151418                                                                                                                                    
PTPN7ENSG00000143851                                                                                                                                    
PIK3C2BENSG00000133056                                                                                                                                    
GAD2ENSG00000136750                                                                                                                                    
VCLENSG00000035403                                                                                                                                    
PTENENSG00000171862      1    1    1        1            1    1    1    1    1        1            1        1            1        1    1    1                1    1      
FKBP2ENSG00000173486                                                                                                                                    
SSH3ENSG00000172830      1                                                                                                                              
PPP1CAENSG00000172531                                                                                                                                    
MMP10ENSG00000166670                                                                                                                                    
CACNB3ENSG00000167535                                                                                                                                    
APPL2ENSG00000136044                                                                                                                                    

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