Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
SNRKENSG00000163788                                                                                                                                    
PLSCR2ENSG00000163746                                                                                                                                    
SNCAENSG00000145335                                                                                                                                    
FGGENSG00000171557                                                                                                                                    
ELNENSG00000049540                                                                                                                                    
TRIB1ENSG00000173334                                                                                                                                    
WNK2ENSG00000165238                                                                                                                                    
PNCKENSG00000130822                                                                                                                                    
MAP3K6ENSG00000142733                                                                                                                                    
MLK4ENSG00000143674                                                                                                                                    
PDE6CENSG00000095464                                                                                                                                    
OR8K3ENSG00000280314                                                                                                                                    
APOC3ENSG00000110245                                                                                                                                    
APOA1ENSG00000118137                                                                                                                                    
ENDOUENSG00000111405                                                                                                                                    
DHHENSG00000139549                                                                                                                                    
TNS2ENSG00000111077                                                                                                                                    
NR2C1ENSG00000120798                                                                                                                                    
POLEENSG00000177084                                                                                                                                    
GZMBENSG00000100453                                                                                                                                    

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