Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
MAPK15ENSG00000181085                                                                                                                                    
MTMR1ENSG00000063601                                                                                                                                    
PCSK9ENSG00000169174                                                                                                                                    
PRKACBENSG00000142875                                                                                                                                    
MYO3AENSG00000095777                                                                                                                                    
MASTLENSG00000120539                                                                                                                                    
PRKG1ENSG00000185532                                                                                                                                    
DKK1ENSG00000107984                                                                                                                                    
TUBENSG00000166402                                                                                                                                    
OSGEPENSG00000092094                                                                                                                                    
PAK6ENSG00000137843                                                                                                                                    
ALOX12ENSG00000108839                                                                                                                                    
DUSP3ENSG00000108861                                                                                                                                    
MAP2K7ENSG00000076984                                                                                                          1                          
PAK4ENSG00000130669                                                                                                                                    
ACP1ENSG00000143727                                                                                                                                    
ROCK2ENSG00000134318                                                                                                                                    
CYP24A1ENSG00000019186                                                                                                                                    
HUNKENSG00000142149                                                                                                                                    
ADRBK2ENSG00000100077                                                                                                                                    

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