Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
COL5A1ENSG00000130635                                                                                                                                    
PAEPENSG00000122133                                                                                                                                    
LCN9ENSG00000148386                                                                                                                                    
LCN8ENSG00000204001                                                                                                                                    
SIGMAR1ENSG00000147955                                                                                                                                    
SMPD3ENSG00000103056                                                                                                                                    
PTPN2ENSG00000175354                                                                                                                                    
OR10C1ENSG00000206474                                                                                                                                    
CYP4A11ENSG00000187048                                                                                                                                    
VAMP1ENSG00000139190                                                                                                                                    
FKBP11ENSG00000134285                                                                                                                                    
DIO2ENSG00000211448                                                                  1                                                                  
CYP4F2ENSG00000186115                                                                                                                                    
STIM2ENSG00000109689                                                                                                                          1          
ATP6AP2ENSG00000182220                                                                  1                                                                  
OPN1MW2ENSG00000166160                                                                                                                                    
DIO1ENSG00000211452                                                                                                                                    
APH1AENSG00000117362                                                                                                                                    
ADCY10ENSG00000143199                                                                                                                                    
SLC35G1ENSG00000176273                                                                                                                                    

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