Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
TPSAB1ENSG00000172236                                                                                                                                    
PRSS22ENSG00000005001                                                                                                                                    
MMP25ENSG00000008516                                                                                                                                    
DNASE1ENSG00000213918                                                                                                                                    
PRSS36ENSG00000178226                                                                                                                                    
NTN1ENSG00000065320                                                                                                                                    
CCL7ENSG00000108688                                                                                                                                    
GH2ENSG00000136487                                                                                                                                    
FASNENSG00000169710                                                                                                      1                              
CSNK1DENSG00000141551                                                                                                                                    
PRKACAENSG00000072062                                                                                                                                    
MRC1ENSG00000260314                                                                                                                                    
PRKCEENSG00000171132                                                                                                                                    
ZAP70ENSG00000115085                                                                                                                                    
CST9LENSG00000101435                                                                                                                                    
WFDC2ENSG00000101443                                                                                                                                    
CTSAENSG00000064601                                                                                                                                    
SPPL2BENSG00000005206                                                                                                                                    
WNT7BENSG00000188064                                                                                                                                    
SPINK8ENSG00000229453                                                                                                                                    

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