Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
SLC37A1ENSG00000160190                                                                                                                                    
IL22RA2ENSG00000164485                                                                                                                                    
ATP13A5ENSG00000187527                                                                                                                                    
PRSS58ENSG00000258223                                                                                                                                    
PENKENSG00000181195                                                                                                                                    
BMP15ENSG00000130385                                                                                                                                    
SMPD2ENSG00000135587                                                                                                                                    
NODALENSG00000156574                                                                                                                                    
HILPDAENSG00000135245                                                                                                                                    
P4HA1ENSG00000122884                                                                                                                                    
FOLR3ENSG00000110203                                                                                                                                    
INHBCENSG00000175189                                                                                                                                    
INHBEENSG00000139269                                                                                                                                    
AQP7ENSG00000165269                                                                                                                                    
ERO1LENSG00000197930                                                                                                                                    
FAM20AENSG00000108950                                                                                                                                    
AZU1ENSG00000172232                                                                                                                                    
CDCP2ENSG00000157211                                                                                                                                    
KLK12ENSG00000186474                                                                                                                                    
PDE3BENSG00000152270                                                                      1                                                              

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