Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
BMP2ENSG00000125845                                                                                                                                    
DEFB116ENSG00000215545                                                                                                                                    
LBPENSG00000129988                                                                                                                                    
HRGENSG00000113905                                                                                                                                    
ADIPOQENSG00000181092                                                                                                                                    
IL4ENSG00000113520                                                                                                                                    
LY86ENSG00000112799                                                                                                                                    
IL17AENSG00000112115                                                                                                                                    
SFRP4ENSG00000106483                                                                                                                                    
DEFB104AENSG00000176782                                                                                                                                    
NRD1ENSG00000078618                                                                                                                                    
ADAMTS7ENSG00000136378                                                                                                                                    
BSPH1ENSG00000188334                                                                                                                                    
PDGFBENSG00000100311                                                                                                                                    
SPARCENSG00000113140                                                                                                                                    
MCOLN3ENSG00000055732                                                                                                                                    
KCNT2ENSG00000162687                                                                                                                                    
KCNH1ENSG00000143473                                                                                                                                    
SYT15ENSG00000204176                                                                                                                                    
SCN8AENSG00000196876                                                                                                                                    

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