Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
ADAM29ENSG00000168594                                                                                                                                    
MEP1AENSG00000112818                                                                                                                                    
ULBP1ENSG00000111981                                                                                                                                    
LRRC4ENSG00000128594                                                                                                                                    
EPHB6ENSG00000106123                                                                                                                                    
ADAM2ENSG00000104755                                                                                                                                    
LINGO2ENSG00000174482                                                                                                                                    
SLC46A2ENSG00000119457                                                                                                                                    
TNFSF15ENSG00000181634                                                                                                                                    
TNFSF8ENSG00000106952                                                                                                                                    
TLR7ENSG00000196664                                                                                                                                    
ADGRG4ENSG00000156920                                                                                                                                    
SLC5A9ENSG00000117834                                                                                                                                    
SLC1A7ENSG00000162383                                                                                                                                    
SLC16A9ENSG00000165449                                                                                                                                    
SLC18A2ENSG00000165646                                                                                                                                    
SLC43A3ENSG00000134802                                                                                                                                    
TECTAENSG00000109927                                                                                                                                    
KCNJ1ENSG00000151704                                                                                                                                    
LRIG3ENSG00000139263                                                                                                                                    

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