Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
EFEMP1ENSG00000115380                                                                                                                                    
FSTL1ENSG00000163430                                                                                                                                    
COL6A5ENSG00000172752                                                                                                                                    
AHSGENSG00000145192                                                                                                                                    
SCUBE3ENSG00000146197                                                                                                                                    
LAMB1ENSG00000091136                                                                                                      1                              
TNFRSF11BENSG00000164761                                                                                                                                    
ORM1ENSG00000229314                                                                                                                                    
DRD2ENSG00000149295                                                                                                                                    
MC4RENSG00000166603                                                                                                                                    
GPR88ENSG00000181656                                                                                                                                    
OPN4ENSG00000122375                                                                                                                                    
OR5AN1ENSG00000176495                                                                                                                                    
PTGDRENSG00000168229                                                                                                                                    
ADGRG5ENSG00000159618                                                                                                                                    
ADGRG3ENSG00000182885                                                                                                                                    
OR1D2ENSG00000184166                                                                                                                                    
FPR1ENSG00000171051                                                                                                                                    
GPR75ENSG00000119737                                                                                                                                    
OPRM1ENSG00000112038                                                                                                                                    

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