Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
TMPRSS9ENSG00000178297                                                                                                                                    
LILRB5ENSG00000105609                                                                                                                                    
SLC22A13ENSG00000172940                                                                                                                                    
GABRR3ENSG00000183185                                                                                                                                    
TMPRSS7ENSG00000176040                                                                                                                                    
ADCY5ENSG00000173175                                                                                                                                    
CLDN18ENSG00000066405                                                                                                                                    
HTR3DENSG00000186090                                                                                                                                    
HTR3CENSG00000178084                                                                                                                                    
HTR3EENSG00000186038                                                                                                                                    
SLC34A2ENSG00000157765                                                                                                                                    
GRID2ENSG00000152208                                                                                                                                    
ASIC5ENSG00000256394                                                                                                                                    
GPM6AENSG00000150625                                                                                                                                    
SLC36A2ENSG00000186335                                                                                                                                    
SLC26A8ENSG00000112053                                                                                                                                    
RHAGENSG00000112077                                                                                                                                    
SLC2A12ENSG00000146411                                                                                                                                    
SLC2A8ENSG00000136856                                                                                                                                    
GLRA4ENSG00000188828                                                                                                                                    

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