Mutation
The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.
Summary of mutation frequency of the PDGs in each cancer type
| Showing page 68 |
first page | previous page | next page | last page |
| HGNC Symbol | Ensembl Gene ID | ACC_Mut% | BLCA_Mut% | BRCA_Mut% | CESC_Mut% | CHOL_Mut% | COAD_Mut% | DLBC_Mut% | ESCA_Mut% | GBM_Mut% | HNSC_Mut% | KICH_Mut% | KIRC_Mut% | KIRP_Mut% | LAML_Mut% | LGG_Mut% | LIHC_Mut% | LUAD_Mut% | LUSC_Mut% | MESO_Mut% | OV_Mut% | PAAD_Mut% | PCPG_Mut% | PRAD_Mut% | READ_Mut% | SARC_Mut% | SKCM_Mut% | STAD_Mut% | TGCT_Mut% | THCA_Mut% | THYM_Mut% | UCEC_Mut% | UCS_Mut% | UVM_Mut% |
| OR5B12 | ENSG00000172362 | 2.22 | 0.76 | 0.21 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.26 | 1.00 | 0.00 | 0.27 | 0.00 | 0.00 | 0.00 | 0.83 | 1.88 | 3.65 | 0.00 | 0.00 | 0.00 | 0.00 | 0.41 | 0.78 | 0.00 | 2.37 | 0.54 | 0.00 | 0.00 | 0.00 | 0.89 | 0.00 | 0.00 |
| OR5B21 | ENSG00000198283 | 0.00 | 0.76 | 0.10 | 0.73 | 0.00 | 0.65 | 2.70 | 0.55 | 0.26 | 0.20 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.28 | 2.07 | 1.93 | 0.00 | 0.74 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.42 | 0.27 | 0.00 | 0.00 | 0.00 | 1.11 | 0.00 | 1.25 |
| OR5A1 | ENSG00000172320 | 0.00 | 1.27 | 0.62 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.03 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.39 | 0.28 | 2.45 | 2.15 | 0.00 | 0.74 | 0.57 | 0.00 | 0.41 | 0.00 | 1.29 | 0.71 | 0.81 | 0.00 | 0.00 | 0.00 | 0.67 | 0.00 | 0.00 |
| OR4D10 | ENSG00000254466 | 0.00 | 1.02 | 0.41 | 0.00 | 0.00 | 0.97 | 2.70 | 0.00 | 0.52 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.28 | 2.45 | 2.79 | 0.00 | 0.49 | 0.00 | 0.00 | 0.20 | 0.00 | 0.43 | 2.13 | 0.27 | 0.00 | 0.00 | 0.00 | 0.22 | 0.00 | 0.00 |
| OR4D11 | ENSG00000176200 | 0.00 | 1.02 | 0.21 | 0.00 | 0.00 | 0.65 | 0.00 | 0.55 | 0.52 | 1.20 | 0.00 | 0.27 | 0.36 | 0.74 | 0.20 | 0.00 | 2.45 | 2.15 | 0.00 | 0.49 | 0.00 | 0.00 | 0.00 | 0.78 | 0.43 | 1.66 | 0.27 | 0.00 | 0.00 | 0.00 | 0.67 | 0.00 | 0.00 |
| OR4D9 | ENSG00000172742 | 0.00 | 0.25 | 0.21 | 0.73 | 0.00 | 0.97 | 0.00 | 1.10 | 0.26 | 0.60 | 0.00 | 0.00 | 0.36 | 0.00 | 0.20 | 0.00 | 2.26 | 1.72 | 0.00 | 0.49 | 0.57 | 0.00 | 0.20 | 0.78 | 0.00 | 1.42 | 0.27 | 0.00 | 0.20 | 0.00 | 0.67 | 1.82 | 0.00 |
| OR10V1 | ENSG00000172289 | 0.00 | 0.76 | 0.21 | 0.00 | 0.00 | 0.65 | 0.00 | 0.00 | 0.52 | 0.20 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.69 | 1.93 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.71 | 0.27 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| P2RY6 | ENSG00000171631 | 0.00 | 0.25 | 0.10 | 0.00 | 0.00 | 0.97 | 2.70 | 1.10 | 0.52 | 0.40 | 0.00 | 0.00 | 0.36 | 0.00 | 0.20 | 0.00 | 0.19 | 0.43 | 0.00 | 0.49 | 0.57 | 0.56 | 0.00 | 0.78 | 0.43 | 0.24 | 1.36 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| OR2AT4 | ENSG00000171561 | 1.11 | 0.00 | 0.21 | 0.36 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.36 | 0.00 | 0.20 | 0.00 | 0.19 | 0.86 | 0.00 | 0.25 | 0.00 | 0.00 | 0.20 | 0.00 | 0.43 | 1.18 | 0.81 | 0.00 | 0.20 | 0.00 | 0.67 | 0.00 | 0.00 |
| OR6X1 | ENSG00000221931 | 0.00 | 0.25 | 0.52 | 0.00 | 0.00 | 0.00 | 0.00 | 0.55 | 0.00 | 0.60 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.56 | 1.32 | 1.50 | 0.00 | 0.00 | 0.00 | 0.00 | 0.41 | 0.78 | 0.86 | 1.66 | 1.36 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| OR6M1 | ENSG00000196099 | 0.00 | 1.02 | 0.10 | 0.36 | 0.00 | 0.32 | 2.70 | 1.10 | 0.52 | 0.40 | 0.00 | 0.27 | 0.00 | 0.74 | 0.20 | 0.83 | 1.13 | 2.58 | 0.00 | 0.25 | 0.00 | 0.00 | 0.20 | 2.34 | 0.00 | 1.42 | 1.08 | 0.00 | 0.00 | 0.83 | 0.67 | 0.00 | 0.00 |
| OR4D5 | ENSG00000171014 | 0.00 | 1.02 | 0.10 | 0.00 | 0.00 | 0.32 | 2.70 | 1.10 | 1.03 | 0.80 | 0.00 | 0.27 | 0.00 | 0.00 | 0.00 | 0.56 | 1.69 | 4.94 | 0.00 | 0.25 | 0.57 | 0.00 | 0.81 | 0.78 | 0.00 | 4.03 | 2.17 | 0.00 | 0.41 | 0.00 | 0.89 | 0.00 | 0.00 |
| OR6T1 | ENSG00000181499 | 0.00 | 0.51 | 0.31 | 0.36 | 2.86 | 1.94 | 0.00 | 1.10 | 0.26 | 1.39 | 0.00 | 0.27 | 0.00 | 0.74 | 0.00 | 0.28 | 2.64 | 3.43 | 0.00 | 0.00 | 0.57 | 0.00 | 0.20 | 1.56 | 0.86 | 4.03 | 0.81 | 0.00 | 0.00 | 0.00 | 0.89 | 0.00 | 0.00 |
| OR10S1 | ENSG00000196248 | 1.11 | 0.76 | 0.31 | 0.73 | 0.00 | 0.32 | 0.00 | 0.55 | 0.77 | 0.80 | 0.00 | 0.54 | 0.36 | 0.00 | 0.20 | 0.56 | 1.69 | 4.29 | 0.00 | 1.23 | 0.00 | 0.00 | 0.00 | 0.00 | 0.43 | 2.61 | 2.17 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| OR10G9 | ENSG00000236981 | 0.00 | 0.25 | 0.21 | 0.00 | 0.00 | 1.61 | 0.00 | 1.10 | 0.26 | 0.20 | 0.00 | 0.00 | 0.36 | 0.00 | 0.00 | 0.00 | 2.07 | 3.86 | 0.00 | 0.00 | 1.15 | 0.00 | 0.00 | 0.00 | 0.43 | 1.90 | 1.36 | 0.00 | 0.00 | 0.00 | 1.33 | 0.00 | 0.00 |
| OR10G8 | ENSG00000234560 | 0.00 | 0.76 | 0.00 | 0.73 | 0.00 | 0.32 | 2.70 | 2.76 | 0.77 | 1.39 | 0.00 | 0.27 | 0.36 | 0.00 | 0.39 | 1.11 | 3.77 | 4.72 | 0.00 | 0.49 | 0.00 | 0.56 | 1.02 | 1.56 | 0.86 | 3.55 | 1.36 | 0.00 | 0.00 | 0.00 | 1.11 | 0.00 | 0.00 |
| OR10G7 | ENSG00000182634 | 0.00 | 1.02 | 0.21 | 1.82 | 0.00 | 0.32 | 2.70 | 1.66 | 0.26 | 0.20 | 0.00 | 1.63 | 0.36 | 0.00 | 0.00 | 1.11 | 2.26 | 4.51 | 0.00 | 0.25 | 0.57 | 0.00 | 0.00 | 2.34 | 0.43 | 2.13 | 0.54 | 0.00 | 0.00 | 0.00 | 0.89 | 1.82 | 0.00 |
| OR8B8 | ENSG00000197125 | 0.00 | 0.76 | 0.21 | 0.73 | 0.00 | 0.97 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.81 | 0.36 | 0.74 | 0.00 | 0.83 | 1.88 | 2.79 | 0.00 | 0.49 | 0.57 | 0.00 | 0.20 | 0.00 | 0.43 | 2.13 | 0.27 | 0.00 | 0.00 | 0.00 | 1.11 | 0.00 | 0.00 |
| OR8A1 | ENSG00000196119 | 1.11 | 0.51 | 0.10 | 0.00 | 0.00 | 0.32 | 0.00 | 0.00 | 0.52 | 0.20 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.28 | 0.94 | 2.79 | 0.00 | 0.98 | 0.00 | 0.56 | 0.20 | 0.00 | 0.43 | 3.08 | 1.08 | 0.00 | 0.00 | 0.00 | 0.67 | 1.82 | 0.00 |
| AQP2 | ENSG00000167580 | 1.11 | 0.76 | 0.10 | 1.09 | 0.00 | 0.65 | 0.00 | 0.00 | 0.52 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.56 | 0.19 | 0.21 | 0.00 | 0.74 | 0.00 | 0.00 | 0.20 | 0.78 | 0.00 | 0.95 | 0.27 | 0.00 | 0.00 | 0.00 | 0.22 | 0.00 | 0.00 |
|
Showing page 68 |
first page | previous page | next page | last page |
Copyright © 2020 University of Pennsylvania. All Rights Reserved.