Mutation
The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.
Summary of mutation frequency of the PDGs in each cancer type
| Showing page 299 |
first page | previous page | next page | last page |
| HGNC Symbol | Ensembl Gene ID | ACC_Mut% | BLCA_Mut% | BRCA_Mut% | CESC_Mut% | CHOL_Mut% | COAD_Mut% | DLBC_Mut% | ESCA_Mut% | GBM_Mut% | HNSC_Mut% | KICH_Mut% | KIRC_Mut% | KIRP_Mut% | LAML_Mut% | LGG_Mut% | LIHC_Mut% | LUAD_Mut% | LUSC_Mut% | MESO_Mut% | OV_Mut% | PAAD_Mut% | PCPG_Mut% | PRAD_Mut% | READ_Mut% | SARC_Mut% | SKCM_Mut% | STAD_Mut% | TGCT_Mut% | THCA_Mut% | THYM_Mut% | UCEC_Mut% | UCS_Mut% | UVM_Mut% |
| DPF3 | ENSG00000205683 | 0.00 | 0.51 | 0.10 | 0.73 | 2.86 | 0.32 | 0.00 | 1.66 | 0.00 | 0.40 | 0.00 | 0.00 | 0.71 | 0.00 | 0.00 | 0.28 | 1.51 | 2.79 | 0.00 | 0.98 | 0.00 | 0.00 | 0.00 | 0.78 | 0.00 | 1.66 | 1.08 | 0.00 | 0.20 | 0.00 | 1.55 | 0.00 | 0.00 |
| C14orf169 | ENSG00000170468 | |||||||||||||||||||||||||||||||||
| UBR7 | ENSG00000012963 | 0.00 | 0.25 | 0.31 | 0.36 | 0.00 | 0.32 | 0.00 | 0.00 | 0.00 | 0.40 | 0.00 | 0.27 | 0.00 | 0.00 | 0.20 | 0.00 | 0.56 | 0.43 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.22 | 0.00 | 0.00 |
| SETD3 | ENSG00000183576 | 0.00 | 0.51 | 0.21 | 0.36 | 0.00 | 0.65 | 0.00 | 0.55 | 0.26 | 0.80 | 0.00 | 0.27 | 0.36 | 0.74 | 0.20 | 0.28 | 0.56 | 0.64 | 0.00 | 0.49 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.71 | 0.81 | 0.69 | 0.00 | 0.00 | 0.67 | 0.00 | 0.00 |
| MTA1 | ENSG00000182979 | 0.00 | 1.02 | 0.00 | 0.00 | 0.00 | 0.97 | 0.00 | 0.55 | 0.26 | 1.00 | 0.00 | 0.54 | 1.07 | 0.00 | 0.00 | 0.83 | 0.75 | 0.64 | 0.00 | 0.74 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 1.18 | 0.54 | 0.00 | 0.00 | 0.00 | 2.88 | 0.00 | 0.00 |
| BAHD1 | ENSG00000140320 | 0.00 | 1.27 | 0.21 | 0.36 | 0.00 | 0.00 | 0.00 | 0.00 | 1.03 | 0.20 | 0.00 | 0.27 | 1.07 | 0.00 | 0.20 | 0.83 | 0.56 | 0.64 | 0.00 | 0.74 | 0.57 | 0.56 | 0.41 | 0.78 | 0.43 | 0.71 | 0.54 | 0.69 | 0.00 | 0.00 | 2.00 | 0.00 | 0.00 |
| PYGO1 | ENSG00000171016 | 0.00 | 1.53 | 0.00 | 0.36 | 0.00 | 0.00 | 0.00 | 0.55 | 0.26 | 1.00 | 0.00 | 0.27 | 0.00 | 0.00 | 0.00 | 0.56 | 0.56 | 0.64 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.78 | 0.00 | 1.42 | 0.00 | 0.00 | 0.20 | 0.00 | 1.11 | 0.00 | 0.00 |
| MORF4L1 | ENSG00000185787 | 0.00 | 1.27 | 0.21 | 0.36 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.40 | 0.00 | 0.54 | 0.36 | 0.00 | 0.00 | 0.28 | 1.13 | 1.07 | 0.00 | 0.25 | 0.00 | 0.00 | 0.00 | 0.00 | 0.43 | 0.00 | 0.27 | 0.00 | 0.00 | 0.00 | 0.67 | 0.00 | 0.00 |
| HDGFRP3 | ENSG00000166503 | 0.00 | 0.25 | 0.21 | 0.00 | 0.00 | 0.32 | 0.00 | 0.55 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.28 | 0.56 | 0.21 | 0.00 | 0.25 | 0.00 | 0.00 | 0.00 | 0.00 | 0.43 | 0.47 | 0.54 | 0.00 | 0.00 | 0.00 | 0.44 | 1.82 | 0.00 |
| EEF2KMT | ENSG00000118894 | 0.00 | 0.51 | 0.00 | 0.36 | 0.00 | 0.32 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 0.36 | 0.00 | 0.00 | 0.00 | 0.19 | 0.43 | 0.00 | 0.00 | 0.00 | 0.00 | 0.41 | 0.00 | 0.00 | 1.42 | 0.27 | 0.00 | 0.00 | 0.00 | 0.67 | 0.00 | 0.00 |
| CCDC101 | ENSG00000176476 | 0.00 | 0.51 | 0.10 | 0.73 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.43 | 1.23 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 0.47 | 0.27 | 0.00 | 0.00 | 0.00 | 1.33 | 0.00 | 0.00 |
| FBXL19 | ENSG00000099364 | 0.00 | 1.02 | 0.41 | 1.46 | 0.00 | 0.65 | 0.00 | 0.55 | 0.26 | 0.20 | 0.00 | 0.27 | 0.36 | 0.74 | 0.00 | 0.56 | 0.38 | 0.43 | 0.00 | 0.98 | 0.00 | 0.00 | 0.20 | 0.78 | 0.00 | 0.71 | 0.00 | 0.00 | 0.00 | 0.00 | 1.11 | 0.00 | 0.00 |
| SETD1A | ENSG00000099381 | 0.00 | 1.78 | 0.00 | 0.73 | 0.00 | 0.65 | 2.70 | 1.10 | 1.03 | 1.79 | 1.54 | 0.27 | 1.42 | 0.00 | 0.00 | 1.11 | 2.07 | 3.43 | 0.00 | 1.23 | 1.15 | 0.56 | 0.20 | 0.00 | 0.86 | 4.74 | 1.36 | 0.00 | 0.20 | 0.00 | 2.00 | 0.00 | 0.00 |
| KAT8 | ENSG00000103510 | 0.00 | 1.53 | 0.21 | 0.73 | 0.00 | 0.00 | 0.00 | 1.10 | 0.00 | 0.40 | 0.00 | 0.27 | 0.36 | 0.00 | 0.00 | 0.28 | 0.38 | 1.07 | 0.00 | 0.49 | 0.00 | 0.00 | 0.00 | 0.78 | 0.00 | 1.18 | 1.63 | 0.00 | 0.20 | 0.00 | 0.89 | 0.00 | 0.00 |
| SETD6 | ENSG00000103037 | 0.00 | 0.76 | 0.10 | 0.36 | 0.00 | 0.00 | 0.00 | 0.00 | 0.52 | 0.60 | 1.54 | 0.27 | 0.00 | 0.00 | 0.00 | 0.56 | 0.56 | 0.64 | 0.00 | 0.25 | 0.00 | 0.00 | 0.00 | 0.00 | 0.43 | 0.00 | 0.54 | 0.00 | 0.00 | 0.00 | 0.89 | 0.00 | 0.00 |
| PRDM7 | ENSG00000126856 | 0.00 | 0.76 | 0.21 | 0.73 | 0.00 | 0.32 | 0.00 | 0.55 | 0.26 | 0.40 | 0.00 | 0.54 | 0.71 | 0.74 | 0.20 | 0.28 | 0.94 | 0.21 | 0.00 | 0.74 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.47 | 0.00 | 0.69 | 0.00 | 0.00 | 0.22 | 0.00 | 0.00 |
| PHF23 | ENSG00000040633 | 0.00 | 0.25 | 0.00 | 0.36 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.60 | 0.00 | 0.54 | 0.00 | 0.00 | 0.00 | 0.83 | 0.75 | 0.21 | 0.00 | 0.49 | 0.00 | 0.00 | 0.41 | 0.00 | 0.43 | 0.24 | 0.27 | 0.69 | 0.20 | 0.00 | 1.55 | 0.00 | 0.00 |
| FXR2 | ENSG00000129245 | 2.22 | 1.02 | 0.41 | 0.00 | 0.00 | 0.00 | 0.00 | 0.55 | 0.26 | 0.60 | 0.00 | 0.00 | 0.71 | 0.00 | 0.00 | 0.28 | 0.19 | 0.64 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.43 | 0.71 | 0.27 | 0.00 | 0.00 | 0.00 | 1.55 | 0.00 | 0.00 |
| KDM6B | ENSG00000132510 | 2.22 | 1.27 | 0.41 | 0.73 | 0.00 | 1.61 | 0.00 | 1.10 | 0.77 | 1.39 | 0.00 | 0.27 | 1.07 | 0.00 | 0.39 | 0.56 | 2.07 | 1.29 | 0.00 | 0.98 | 0.57 | 1.12 | 0.41 | 0.00 | 0.00 | 4.03 | 1.36 | 0.00 | 0.20 | 0.00 | 4.43 | 1.82 | 0.00 |
| RAI1 | ENSG00000108557 | 0.00 | 4.07 | 0.52 | 1.82 | 0.00 | 0.32 | 2.70 | 0.55 | 0.52 | 1.20 | 0.00 | 0.81 | 1.78 | 0.74 | 0.59 | 0.56 | 0.75 | 2.15 | 1.23 | 0.74 | 0.00 | 1.12 | 0.20 | 0.00 | 0.86 | 4.74 | 1.63 | 0.00 | 0.20 | 0.83 | 4.88 | 0.00 | 0.00 |
|
Showing page 299 |
first page | previous page | next page | last page |
Copyright © 2020 University of Pennsylvania. All Rights Reserved.