Mutation
The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.
Summary of mutation frequency of the PDGs in each cancer type
| Showing page 278 |
first page | previous page | next page | last page |
| HGNC Symbol | Ensembl Gene ID | ACC_Mut% | BLCA_Mut% | BRCA_Mut% | CESC_Mut% | CHOL_Mut% | COAD_Mut% | DLBC_Mut% | ESCA_Mut% | GBM_Mut% | HNSC_Mut% | KICH_Mut% | KIRC_Mut% | KIRP_Mut% | LAML_Mut% | LGG_Mut% | LIHC_Mut% | LUAD_Mut% | LUSC_Mut% | MESO_Mut% | OV_Mut% | PAAD_Mut% | PCPG_Mut% | PRAD_Mut% | READ_Mut% | SARC_Mut% | SKCM_Mut% | STAD_Mut% | TGCT_Mut% | THCA_Mut% | THYM_Mut% | UCEC_Mut% | UCS_Mut% | UVM_Mut% |
| MTRNR2L3 | ENSG00000256222 | |||||||||||||||||||||||||||||||||
| PCK1 | ENSG00000124253 | 1.11 | 2.04 | 0.41 | 0.00 | 0.00 | 0.00 | 0.00 | 0.55 | 1.03 | 0.00 | 0.00 | 1.36 | 2.14 | 0.00 | 0.20 | 1.39 | 3.20 | 1.93 | 0.00 | 0.74 | 0.00 | 0.56 | 0.00 | 0.78 | 0.43 | 1.42 | 0.54 | 0.00 | 0.00 | 0.00 | 0.89 | 0.00 | 0.00 |
| PSMA7 | ENSG00000101182 | 0.00 | 0.25 | 0.10 | 0.36 | 0.00 | 0.65 | 0.00 | 0.55 | 0.26 | 0.00 | 0.00 | 0.00 | 0.36 | 0.00 | 0.00 | 0.28 | 0.94 | 0.00 | 0.00 | 0.25 | 0.00 | 0.56 | 0.00 | 0.00 | 0.00 | 0.24 | 0.27 | 0.00 | 0.00 | 0.00 | 0.67 | 0.00 | 0.00 |
| COL20A1 | ENSG00000101203 | 2.22 | 0.51 | 0.52 | 1.82 | 0.00 | 2.90 | 0.00 | 1.66 | 0.77 | 0.40 | 1.54 | 0.54 | 0.36 | 0.00 | 0.00 | 1.94 | 2.82 | 4.08 | 0.00 | 0.00 | 0.00 | 0.56 | 0.20 | 0.00 | 0.00 | 4.98 | 1.90 | 0.00 | 0.41 | 0.00 | 2.66 | 1.82 | 0.00 |
| MYT1 | ENSG00000196132 | 0.00 | 2.29 | 0.72 | 1.09 | 0.00 | 1.94 | 0.00 | 1.10 | 1.03 | 1.39 | 1.54 | 0.27 | 2.14 | 0.00 | 0.98 | 1.11 | 3.58 | 1.93 | 0.00 | 0.98 | 0.57 | 0.00 | 0.20 | 0.00 | 0.00 | 3.79 | 2.71 | 0.00 | 0.00 | 0.83 | 2.22 | 0.00 | 0.00 |
| ADAMTS5 | ENSG00000154736 | 0.00 | 2.04 | 0.72 | 1.09 | 0.00 | 2.90 | 2.70 | 0.55 | 0.52 | 1.59 | 0.00 | 1.08 | 0.36 | 0.00 | 0.39 | 0.56 | 4.71 | 3.00 | 0.00 | 0.98 | 1.15 | 0.00 | 0.20 | 1.56 | 0.00 | 2.61 | 4.07 | 0.69 | 0.00 | 0.00 | 2.00 | 0.00 | 0.00 |
| MORC3 | ENSG00000159256 | 0.00 | 2.04 | 0.31 | 0.73 | 0.00 | 1.61 | 0.00 | 1.10 | 0.26 | 1.00 | 0.00 | 0.54 | 0.36 | 0.00 | 0.00 | 0.83 | 0.94 | 1.07 | 0.00 | 0.49 | 0.00 | 0.56 | 0.20 | 0.78 | 1.29 | 1.18 | 0.54 | 0.69 | 0.00 | 0.00 | 1.33 | 0.00 | 1.25 |
| HLCS | ENSG00000159267 | 0.00 | 2.29 | 0.10 | 1.82 | 0.00 | 0.97 | 0.00 | 0.00 | 0.26 | 0.20 | 0.00 | 0.27 | 0.36 | 0.00 | 0.00 | 0.56 | 0.38 | 1.50 | 0.00 | 0.49 | 0.57 | 0.00 | 0.20 | 0.78 | 0.00 | 1.90 | 0.54 | 0.00 | 0.20 | 0.00 | 0.67 | 0.00 | 0.00 |
| ERG | ENSG00000157554 | 1.11 | 1.53 | 0.41 | 0.36 | 0.00 | 0.65 | 2.70 | 1.66 | 1.55 | 0.20 | 1.54 | 0.27 | 0.36 | 0.00 | 0.39 | 0.56 | 1.32 | 0.86 | 1.23 | 0.49 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 2.13 | 0.54 | 0.00 | 0.20 | 0.00 | 0.89 | 0.00 | 0.00 |
| CSTB | ENSG00000160213 | 0.00 | 0.25 | 0.00 | 0.36 | 0.00 | 0.32 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.56 | 0.19 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.22 | 0.00 | 0.00 |
| DGCR6 | ENSG00000183628 | 0.00 | 0.51 | 0.10 | 0.36 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.43 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| KLHL22 | ENSG00000099910 | 0.00 | 0.51 | 0.00 | 0.36 | 0.00 | 0.65 | 0.00 | 1.10 | 0.26 | 0.80 | 0.00 | 0.27 | 0.00 | 0.00 | 0.00 | 0.28 | 0.94 | 1.29 | 0.00 | 0.49 | 0.00 | 0.00 | 0.20 | 0.78 | 0.00 | 2.13 | 0.81 | 0.00 | 0.20 | 0.00 | 0.89 | 1.82 | 0.00 |
| MMP11 | ENSG00000099953 | 0.00 | 0.25 | 0.21 | 0.73 | 0.00 | 0.32 | 0.00 | 0.55 | 0.00 | 0.00 | 0.00 | 0.54 | 0.71 | 0.00 | 0.00 | 0.28 | 0.38 | 0.86 | 0.00 | 0.00 | 0.00 | 0.00 | 0.41 | 1.56 | 0.00 | 1.42 | 0.54 | 0.69 | 0.20 | 0.00 | 0.89 | 0.00 | 0.00 |
| GSTT2B | ENSG00000133433 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.32 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| LIMK2 | ENSG00000182541 | 0.00 | 0.76 | 0.31 | 0.36 | 0.00 | 0.00 | 0.00 | 1.10 | 0.00 | 0.60 | 0.00 | 0.00 | 0.36 | 0.00 | 0.00 | 0.56 | 0.38 | 0.86 | 0.00 | 0.25 | 0.00 | 0.00 | 0.41 | 2.34 | 0.00 | 1.66 | 0.00 | 0.00 | 0.00 | 0.83 | 2.22 | 0.00 | 0.00 |
| TXN2 | ENSG00000100348 | 0.00 | 0.51 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.26 | 0.00 | 0.00 | 0.00 | 0.36 | 0.00 | 0.00 | 0.83 | 0.19 | 0.43 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.22 | 1.82 | 1.25 |
| MPST | ENSG00000128309 | 0.00 | 0.25 | 0.10 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.27 | 0.00 | 0.00 | 0.00 | 0.28 | 0.00 | 0.21 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.71 | 0.27 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| H1F0 | ENSG00000189060 | 0.00 | 0.51 | 0.00 | 0.36 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.28 | 0.38 | 0.21 | 0.00 | 0.00 | 0.00 | 0.56 | 0.20 | 0.00 | 0.00 | 0.47 | 0.27 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| APOBEC3A | ENSG00000128383 | 0.00 | 0.25 | 0.21 | 0.00 | 0.00 | 0.65 | 0.00 | 0.00 | 0.26 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.28 | 0.56 | 0.21 | 0.00 | 0.25 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.47 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| APOBEC3G | ENSG00000239713 | 0.00 | 0.25 | 0.21 | 1.82 | 0.00 | 0.65 | 0.00 | 1.10 | 0.26 | 0.20 | 0.00 | 0.00 | 0.00 | 0.74 | 0.00 | 0.28 | 0.56 | 0.43 | 0.00 | 0.25 | 0.00 | 0.00 | 0.00 | 0.78 | 0.00 | 0.71 | 0.00 | 0.00 | 0.20 | 0.00 | 0.67 | 0.00 | 0.00 |
|
Showing page 278 |
first page | previous page | next page | last page |
Copyright © 2020 University of Pennsylvania. All Rights Reserved.