Mutation
The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.
Summary of mutation frequency of the PDGs in each cancer type
| Showing page 240 |
first page | previous page | next page | last page |
| HGNC Symbol | Ensembl Gene ID | ACC_Mut% | BLCA_Mut% | BRCA_Mut% | CESC_Mut% | CHOL_Mut% | COAD_Mut% | DLBC_Mut% | ESCA_Mut% | GBM_Mut% | HNSC_Mut% | KICH_Mut% | KIRC_Mut% | KIRP_Mut% | LAML_Mut% | LGG_Mut% | LIHC_Mut% | LUAD_Mut% | LUSC_Mut% | MESO_Mut% | OV_Mut% | PAAD_Mut% | PCPG_Mut% | PRAD_Mut% | READ_Mut% | SARC_Mut% | SKCM_Mut% | STAD_Mut% | TGCT_Mut% | THCA_Mut% | THYM_Mut% | UCEC_Mut% | UCS_Mut% | UVM_Mut% |
| CCNB2 | ENSG00000157456 | 0.00 | 0.25 | 0.00 | 0.00 | 0.00 | 0.32 | 0.00 | 0.55 | 0.00 | 0.00 | 0.00 | 1.36 | 0.36 | 0.00 | 0.20 | 0.00 | 0.00 | 0.21 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.43 | 0.47 | 0.00 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| LOXL1 | ENSG00000129038 | 0.00 | 0.51 | 0.10 | 0.00 | 0.00 | 0.97 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.27 | 0.36 | 0.00 | 0.00 | 0.83 | 0.56 | 0.43 | 0.00 | 0.00 | 0.57 | 0.00 | 0.00 | 0.00 | 0.00 | 0.24 | 0.00 | 0.00 | 0.00 | 0.00 | 0.67 | 0.00 | 0.00 |
| BLM | ENSG00000197299 | 0.00 | 3.31 | 1.45 | 0.73 | 0.00 | 0.97 | 0.00 | 2.21 | 1.03 | 1.00 | 0.00 | 0.81 | 0.36 | 0.00 | 0.20 | 0.83 | 1.51 | 1.50 | 0.00 | 0.98 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.18 | 1.63 | 0.00 | 0.00 | 0.00 | 2.22 | 0.00 | 0.00 |
| LRRK1 | ENSG00000154237 | 1.11 | 1.53 | 1.03 | 1.09 | 0.00 | 2.26 | 0.00 | 2.21 | 2.58 | 1.79 | 1.54 | 0.81 | 1.42 | 0.74 | 0.59 | 1.67 | 2.64 | 2.58 | 0.00 | 2.45 | 1.15 | 0.00 | 0.61 | 0.78 | 0.86 | 2.61 | 1.63 | 0.00 | 0.00 | 0.00 | 2.88 | 0.00 | 0.00 |
| DECR2 | ENSG00000242612 | 1.11 | 0.00 | 0.10 | 0.00 | 0.00 | 1.29 | 0.00 | 0.00 | 0.52 | 0.20 | 0.00 | 0.00 | 0.36 | 0.00 | 0.00 | 0.56 | 0.38 | 0.86 | 1.23 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.47 | 0.00 | 0.00 | 0.20 | 0.00 | 1.11 | 0.00 | 0.00 |
| CREBBP | ENSG00000005339 | 1.11 | 11.96 | 1.14 | 6.20 | 0.00 | 2.58 | 13.51 | 3.31 | 1.55 | 5.38 | 0.00 | 0.81 | 2.85 | 2.21 | 0.78 | 1.67 | 3.39 | 6.65 | 1.23 | 3.43 | 0.57 | 0.00 | 0.61 | 2.34 | 0.86 | 5.21 | 1.90 | 1.39 | 0.20 | 0.00 | 5.76 | 3.64 | 0.00 |
| PDILT | ENSG00000169340 | 1.11 | 1.27 | 0.72 | 1.46 | 0.00 | 1.94 | 0.00 | 0.55 | 0.26 | 0.40 | 0.00 | 0.00 | 0.36 | 0.74 | 0.59 | 0.56 | 3.01 | 3.43 | 0.00 | 0.49 | 0.00 | 0.00 | 0.41 | 0.78 | 0.00 | 2.37 | 0.27 | 0.00 | 0.00 | 0.83 | 1.11 | 0.00 | 0.00 |
| RSPRY1 | ENSG00000159579 | 0.00 | 1.78 | 0.00 | 0.73 | 0.00 | 0.32 | 0.00 | 0.00 | 0.26 | 0.80 | 0.00 | 0.81 | 0.71 | 0.00 | 0.20 | 0.00 | 0.94 | 1.07 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.78 | 0.43 | 0.71 | 0.54 | 0.00 | 0.20 | 0.00 | 0.67 | 1.82 | 0.00 |
| CCL22 | ENSG00000102962 | 0.00 | 0.25 | 0.00 | 0.00 | 0.00 | 0.32 | 0.00 | 0.55 | 0.26 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.47 | 0.27 | 0.00 | 0.00 | 0.00 | 0.22 | 0.00 | 0.00 |
| CCL17 | ENSG00000102970 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.32 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.74 | 0.00 | 0.00 | 0.38 | 0.43 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| TK2 | ENSG00000166548 | 0.00 | 0.00 | 0.00 | 0.00 | 2.86 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.71 | 0.00 | 0.00 | 0.00 | 0.19 | 0.00 | 0.00 | 0.49 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.24 | 0.00 | 0.00 | 0.00 | 0.00 | 0.67 | 0.00 | 0.00 |
| SF3B3 | ENSG00000189091 | 0.00 | 4.58 | 0.21 | 0.36 | 0.00 | 0.65 | 0.00 | 1.10 | 0.26 | 1.39 | 0.00 | 0.54 | 0.36 | 0.74 | 0.20 | 1.67 | 1.13 | 1.50 | 1.23 | 0.49 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 1.42 | 0.54 | 0.00 | 0.00 | 0.83 | 1.11 | 0.00 | 0.00 |
| HPR | ENSG00000261701 | 1.11 | 0.51 | 0.21 | 0.73 | 0.00 | 0.32 | 0.00 | 0.55 | 0.00 | 0.80 | 1.54 | 0.00 | 0.00 | 0.00 | 0.00 | 0.28 | 1.32 | 0.43 | 0.00 | 0.00 | 0.57 | 0.00 | 0.20 | 0.00 | 0.00 | 1.90 | 0.54 | 0.69 | 0.00 | 0.00 | 0.89 | 0.00 | 0.00 |
| VAT1L | ENSG00000171724 | 1.11 | 1.27 | 0.00 | 0.73 | 0.00 | 0.00 | 0.00 | 1.10 | 0.00 | 0.20 | 0.00 | 0.00 | 0.36 | 0.00 | 0.00 | 0.83 | 1.13 | 1.93 | 0.00 | 0.25 | 0.00 | 0.00 | 0.00 | 3.13 | 0.00 | 4.50 | 0.81 | 0.00 | 0.00 | 0.00 | 0.89 | 1.82 | 0.00 |
| APRT | ENSG00000198931 | 0.00 | 0.25 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.19 | 0.43 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 0.47 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| ALOX12B | ENSG00000179477 | 0.00 | 0.51 | 0.31 | 1.09 | 0.00 | 0.00 | 0.00 | 0.55 | 0.00 | 0.60 | 0.00 | 0.27 | 1.07 | 0.00 | 0.20 | 0.83 | 1.13 | 0.21 | 0.00 | 0.25 | 0.00 | 0.00 | 0.20 | 1.56 | 1.29 | 1.66 | 0.00 | 0.69 | 0.41 | 0.00 | 1.77 | 0.00 | 0.00 |
| TAOK1 | ENSG00000160551 | 2.22 | 2.29 | 0.62 | 0.36 | 0.00 | 0.32 | 2.70 | 0.55 | 0.26 | 0.80 | 0.00 | 0.00 | 0.00 | 0.00 | 0.39 | 1.11 | 0.94 | 2.36 | 0.00 | 0.49 | 0.57 | 0.00 | 0.20 | 0.78 | 0.43 | 3.08 | 1.90 | 0.00 | 0.00 | 0.00 | 1.33 | 0.00 | 0.00 |
| MMP28 | ENSG00000271447 | |||||||||||||||||||||||||||||||||
| CCL23 | ENSG00000274736 | |||||||||||||||||||||||||||||||||
| DHRS11 | ENSG00000278535 |
|
Showing page 240 |
first page | previous page | next page | last page |
Copyright © 2020 University of Pennsylvania. All Rights Reserved.