Mutation
The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.
Summary of mutation frequency of the PDGs in each cancer type
| Showing page 236 |
first page | previous page | next page | last page |
| HGNC Symbol | Ensembl Gene ID | ACC_Mut% | BLCA_Mut% | BRCA_Mut% | CESC_Mut% | CHOL_Mut% | COAD_Mut% | DLBC_Mut% | ESCA_Mut% | GBM_Mut% | HNSC_Mut% | KICH_Mut% | KIRC_Mut% | KIRP_Mut% | LAML_Mut% | LGG_Mut% | LIHC_Mut% | LUAD_Mut% | LUSC_Mut% | MESO_Mut% | OV_Mut% | PAAD_Mut% | PCPG_Mut% | PRAD_Mut% | READ_Mut% | SARC_Mut% | SKCM_Mut% | STAD_Mut% | TGCT_Mut% | THCA_Mut% | THYM_Mut% | UCEC_Mut% | UCS_Mut% | UVM_Mut% |
| PGA4 | ENSG00000229183 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.22 | 0.00 | 0.00 |
| PGA5 | ENSG00000256713 | 0.00 | 0.00 | 0.21 | 0.00 | 0.00 | 0.32 | 0.00 | 0.00 | 0.00 | 0.40 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.28 | 0.19 | 0.21 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.78 | 0.43 | 0.24 | 0.00 | 0.00 | 0.00 | 0.00 | 0.22 | 0.00 | 0.00 |
| SCGB1D4 | ENSG00000197745 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.40 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.38 | 0.21 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.71 | 0.54 | 0.00 | 0.00 | 0.00 | 0.22 | 0.00 | 0.00 |
| SCGB1A1 | ENSG00000149021 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.38 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.24 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| PLCB3 | ENSG00000149782 | 0.00 | 2.04 | 0.31 | 1.46 | 0.00 | 0.65 | 0.00 | 1.10 | 0.77 | 1.39 | 0.00 | 0.54 | 0.71 | 0.74 | 0.00 | 0.56 | 1.51 | 1.72 | 0.00 | 1.23 | 0.57 | 0.56 | 0.00 | 0.00 | 0.00 | 1.18 | 0.54 | 0.00 | 0.41 | 0.83 | 1.77 | 1.82 | 0.00 |
| PYGM | ENSG00000068976 | 0.00 | 2.54 | 0.72 | 1.46 | 0.00 | 0.65 | 0.00 | 1.10 | 0.52 | 1.59 | 0.00 | 1.36 | 0.36 | 0.00 | 0.00 | 1.11 | 1.13 | 2.36 | 0.00 | 0.74 | 0.00 | 0.00 | 0.00 | 0.00 | 0.43 | 1.66 | 0.81 | 0.00 | 0.00 | 0.83 | 1.55 | 1.82 | 0.00 |
| SCYL1 | ENSG00000142186 | 0.00 | 0.25 | 0.10 | 0.00 | 0.00 | 0.00 | 0.00 | 1.10 | 0.77 | 1.00 | 0.00 | 0.00 | 0.36 | 0.00 | 0.20 | 0.83 | 1.13 | 0.43 | 0.00 | 0.98 | 0.00 | 0.00 | 0.20 | 0.00 | 0.43 | 1.18 | 0.81 | 0.00 | 0.00 | 0.00 | 0.89 | 0.00 | 0.00 |
| MAP3K11 | ENSG00000173327 | 0.00 | 0.51 | 0.41 | 1.46 | 2.86 | 0.32 | 0.00 | 0.55 | 0.26 | 0.60 | 0.00 | 0.81 | 0.00 | 0.74 | 0.00 | 1.39 | 1.13 | 0.64 | 0.00 | 0.25 | 0.00 | 0.00 | 0.20 | 1.56 | 0.86 | 2.84 | 0.81 | 0.00 | 0.00 | 0.00 | 1.33 | 0.00 | 0.00 |
| CTSW | ENSG00000172543 | 0.00 | 0.25 | 0.10 | 0.36 | 0.00 | 0.32 | 0.00 | 0.00 | 0.26 | 0.60 | 0.00 | 0.54 | 0.00 | 0.00 | 0.20 | 0.28 | 0.19 | 1.07 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.95 | 1.36 | 0.69 | 0.00 | 0.00 | 1.11 | 0.00 | 0.00 |
| RPS6KB2 | ENSG00000175634 | 0.00 | 0.25 | 0.41 | 0.36 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.40 | 0.00 | 0.00 | 0.36 | 0.00 | 0.00 | 0.56 | 0.38 | 0.86 | 1.23 | 0.49 | 1.15 | 0.00 | 0.20 | 0.00 | 0.00 | 0.71 | 0.81 | 0.00 | 0.20 | 0.00 | 0.89 | 0.00 | 0.00 |
| GSTP1 | ENSG00000084207 | 0.00 | 0.51 | 0.21 | 0.36 | 0.00 | 0.32 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 0.36 | 0.00 | 0.00 | 0.56 | 0.38 | 0.43 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.47 | 0.27 | 0.00 | 0.00 | 0.00 | 0.22 | 0.00 | 0.00 |
| CCND1 | ENSG00000110092 | 0.00 | 1.27 | 0.10 | 0.73 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.40 | 0.00 | 0.00 | 0.00 | 0.00 | 0.59 | 0.28 | 0.38 | 0.64 | 0.00 | 0.25 | 0.00 | 0.00 | 0.00 | 0.00 | 0.43 | 0.47 | 0.27 | 0.00 | 0.00 | 0.00 | 5.76 | 0.00 | 0.00 |
| FGF3 | ENSG00000186895 | 1.11 | 0.51 | 0.10 | 0.73 | 0.00 | 1.29 | 0.00 | 0.55 | 0.00 | 0.20 | 0.00 | 0.27 | 0.71 | 0.00 | 0.00 | 0.28 | 0.38 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.86 | 0.24 | 0.27 | 0.00 | 0.00 | 0.83 | 0.22 | 0.00 | 0.00 |
| INPPL1 | ENSG00000165458 | 0.00 | 2.04 | 0.72 | 0.73 | 0.00 | 2.26 | 0.00 | 2.21 | 1.03 | 1.39 | 0.00 | 0.81 | 1.07 | 0.00 | 0.39 | 0.56 | 1.32 | 2.79 | 2.47 | 0.74 | 0.00 | 0.00 | 0.41 | 0.00 | 0.43 | 3.55 | 1.08 | 0.00 | 0.00 | 0.00 | 9.31 | 0.00 | 0.00 |
| MTMR2 | ENSG00000087053 | 0.00 | 1.27 | 0.10 | 0.73 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.40 | 0.00 | 0.27 | 1.42 | 0.00 | 0.20 | 0.00 | 0.38 | 0.21 | 0.00 | 0.74 | 0.00 | 0.00 | 0.41 | 0.00 | 0.00 | 0.71 | 0.54 | 0.00 | 0.00 | 0.00 | 0.67 | 0.00 | 0.00 |
| BIRC3 | ENSG00000023445 | 0.00 | 0.76 | 0.21 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.26 | 0.20 | 1.54 | 0.27 | 0.71 | 0.00 | 0.00 | 0.00 | 0.56 | 0.86 | 0.00 | 0.74 | 0.00 | 0.56 | 0.00 | 1.56 | 0.43 | 1.90 | 1.08 | 0.00 | 0.00 | 0.00 | 0.67 | 0.00 | 0.00 |
| MMP3 | ENSG00000149968 | 0.00 | 0.51 | 0.10 | 1.09 | 0.00 | 0.32 | 0.00 | 0.55 | 1.55 | 0.20 | 0.00 | 0.27 | 0.00 | 0.00 | 0.20 | 0.83 | 1.13 | 0.00 | 0.00 | 0.25 | 1.15 | 0.00 | 0.00 | 0.00 | 0.86 | 2.84 | 0.81 | 0.00 | 0.20 | 0.00 | 2.22 | 0.00 | 0.00 |
| APOA5 | ENSG00000110243 | 0.00 | 0.76 | 0.00 | 0.00 | 0.00 | 0.65 | 0.00 | 0.55 | 0.26 | 0.40 | 0.00 | 0.54 | 0.00 | 0.74 | 0.00 | 0.00 | 0.94 | 0.43 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.43 | 0.47 | 0.27 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| APOA4 | ENSG00000110244 | 0.00 | 1.02 | 0.21 | 0.00 | 2.86 | 0.65 | 0.00 | 0.00 | 0.00 | 0.80 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.56 | 1.32 | 1.72 | 0.00 | 0.49 | 0.57 | 0.00 | 0.00 | 0.00 | 0.00 | 2.13 | 0.27 | 0.69 | 0.20 | 0.00 | 0.67 | 0.00 | 1.25 |
| KMT2A | ENSG00000118058 | 4.44 | 9.92 | 1.65 | 1.82 | 0.00 | 3.23 | 5.41 | 3.87 | 1.03 | 4.18 | 0.00 | 1.36 | 1.78 | 0.74 | 0.59 | 2.78 | 5.08 | 4.72 | 1.23 | 3.43 | 1.72 | 0.00 | 1.02 | 0.00 | 1.72 | 9.00 | 4.61 | 0.00 | 1.22 | 0.00 | 4.66 | 0.00 | 0.00 |
|
Showing page 236 |
first page | previous page | next page | last page |
Copyright © 2020 University of Pennsylvania. All Rights Reserved.