Mutation
The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.
Summary of mutation frequency of the PDGs in each cancer type
| Showing page 233 |
first page | previous page | next page | last page |
| HGNC Symbol | Ensembl Gene ID | ACC_Mut% | BLCA_Mut% | BRCA_Mut% | CESC_Mut% | CHOL_Mut% | COAD_Mut% | DLBC_Mut% | ESCA_Mut% | GBM_Mut% | HNSC_Mut% | KICH_Mut% | KIRC_Mut% | KIRP_Mut% | LAML_Mut% | LGG_Mut% | LIHC_Mut% | LUAD_Mut% | LUSC_Mut% | MESO_Mut% | OV_Mut% | PAAD_Mut% | PCPG_Mut% | PRAD_Mut% | READ_Mut% | SARC_Mut% | SKCM_Mut% | STAD_Mut% | TGCT_Mut% | THCA_Mut% | THYM_Mut% | UCEC_Mut% | UCS_Mut% | UVM_Mut% |
| KDM1A | ENSG00000004487 | 0.00 | 1.53 | 0.21 | 1.09 | 0.00 | 0.32 | 0.00 | 1.10 | 0.26 | 0.60 | 0.00 | 0.00 | 0.36 | 0.00 | 0.20 | 0.83 | 0.56 | 1.07 | 0.00 | 0.74 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 0.71 | 0.27 | 0.00 | 0.00 | 0.00 | 0.67 | 0.00 | 0.00 |
| MECR | ENSG00000116353 | 0.00 | 0.76 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.52 | 0.40 | 0.00 | 0.00 | 1.07 | 0.00 | 0.00 | 0.28 | 0.38 | 0.21 | 0.00 | 0.25 | 0.57 | 0.00 | 0.20 | 0.00 | 0.43 | 1.18 | 0.00 | 0.00 | 0.00 | 0.00 | 0.89 | 0.00 | 0.00 |
| FABP3 | ENSG00000121769 | 0.00 | 0.00 | 0.00 | 0.36 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.19 | 0.43 | 0.00 | 0.49 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| AZIN2 | ENSG00000142920 | 0.00 | 1.27 | 0.10 | 0.36 | 0.00 | 0.00 | 0.00 | 0.00 | 0.26 | 0.20 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.19 | 0.43 | 0.00 | 1.23 | 0.00 | 0.00 | 0.20 | 0.00 | 0.43 | 0.71 | 0.27 | 0.00 | 0.20 | 0.00 | 0.44 | 0.00 | 0.00 |
| IPP | ENSG00000197429 | 1.11 | 0.76 | 0.31 | 0.73 | 0.00 | 0.65 | 0.00 | 1.66 | 0.26 | 0.80 | 0.00 | 0.81 | 0.71 | 0.00 | 0.20 | 1.11 | 0.75 | 1.07 | 0.00 | 1.23 | 0.00 | 0.00 | 0.00 | 0.78 | 0.00 | 1.18 | 0.00 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| INSL5 | ENSG00000172410 | 0.00 | 0.25 | 0.21 | 0.36 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.28 | 1.13 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.24 | 0.54 | 0.00 | 0.00 | 0.00 | 0.22 | 0.00 | 0.00 |
| CRYZ | ENSG00000116791 | 0.00 | 0.25 | 0.10 | 0.36 | 0.00 | 0.97 | 0.00 | 0.00 | 0.00 | 0.40 | 0.00 | 0.27 | 0.00 | 0.00 | 0.00 | 0.00 | 0.94 | 1.29 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.18 | 0.00 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| BRDT | ENSG00000137948 | 1.11 | 2.29 | 0.41 | 0.36 | 2.86 | 0.32 | 0.00 | 0.00 | 0.77 | 1.20 | 0.00 | 0.54 | 0.00 | 0.00 | 0.00 | 0.83 | 3.20 | 1.93 | 0.00 | 0.74 | 0.00 | 0.00 | 0.00 | 1.56 | 0.00 | 3.32 | 1.36 | 0.00 | 0.41 | 0.00 | 1.55 | 0.00 | 0.00 |
| DPYD | ENSG00000188641 | 2.22 | 1.78 | 0.10 | 0.73 | 0.00 | 2.26 | 5.41 | 1.66 | 0.52 | 2.79 | 0.00 | 0.54 | 0.36 | 0.00 | 0.20 | 1.67 | 2.64 | 2.15 | 0.00 | 0.74 | 1.15 | 0.00 | 0.41 | 2.34 | 0.43 | 13.03 | 2.71 | 0.00 | 0.00 | 0.00 | 2.44 | 0.00 | 0.00 |
| CDC14A | ENSG00000079335 | 0.00 | 1.02 | 0.31 | 0.73 | 0.00 | 0.00 | 0.00 | 0.00 | 0.52 | 0.60 | 0.00 | 0.81 | 0.36 | 0.74 | 0.00 | 0.28 | 1.51 | 0.64 | 0.00 | 0.25 | 0.57 | 0.00 | 0.00 | 1.56 | 0.00 | 2.13 | 1.36 | 0.00 | 0.00 | 0.00 | 2.22 | 0.00 | 0.00 |
| PRMT6 | ENSG00000198890 | 0.00 | 0.51 | 0.31 | 0.00 | 0.00 | 0.65 | 0.00 | 0.00 | 0.00 | 0.40 | 0.00 | 0.27 | 0.71 | 0.00 | 0.00 | 0.83 | 1.13 | 0.43 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.54 | 0.00 | 0.00 | 0.00 | 0.22 | 0.00 | 0.00 |
| AMPD2 | ENSG00000116337 | 0.00 | 0.76 | 0.10 | 0.36 | 0.00 | 0.00 | 2.70 | 1.10 | 0.26 | 0.00 | 3.08 | 0.54 | 0.71 | 0.00 | 0.39 | 0.28 | 1.13 | 0.43 | 0.00 | 0.49 | 0.00 | 0.00 | 0.41 | 0.00 | 0.43 | 0.71 | 0.81 | 0.00 | 0.41 | 0.00 | 1.33 | 0.00 | 0.00 |
| PROK1 | ENSG00000143125 | 0.00 | 0.00 | 0.00 | 0.36 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.40 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.19 | 0.64 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.24 | 0.00 | 0.00 | 0.00 | 0.00 | 0.22 | 0.00 | 0.00 |
| OVGP1 | ENSG00000085465 | 0.00 | 1.02 | 0.21 | 0.36 | 0.00 | 0.32 | 0.00 | 1.10 | 0.00 | 1.00 | 0.00 | 0.00 | 0.71 | 0.00 | 0.20 | 0.28 | 0.38 | 1.50 | 0.00 | 1.23 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 3.55 | 1.08 | 0.00 | 0.20 | 0.83 | 1.33 | 0.00 | 0.00 |
| CAPZA1 | ENSG00000116489 | 0.00 | 0.51 | 0.00 | 0.36 | 0.00 | 0.00 | 0.00 | 0.55 | 0.26 | 0.60 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.11 | 0.38 | 0.43 | 1.23 | 0.25 | 0.57 | 0.00 | 0.41 | 0.78 | 0.00 | 0.24 | 0.27 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| REG4 | ENSG00000134193 | 0.00 | 0.00 | 0.00 | 0.36 | 0.00 | 0.32 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.27 | 0.00 | 0.74 | 0.00 | 0.28 | 0.56 | 0.00 | 0.00 | 0.49 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.42 | 0.00 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| CTSS | ENSG00000163131 | 0.00 | 0.00 | 0.41 | 0.00 | 0.00 | 0.32 | 0.00 | 0.00 | 0.26 | 0.80 | 0.00 | 0.27 | 0.00 | 0.00 | 0.00 | 0.28 | 0.38 | 0.64 | 1.23 | 0.00 | 0.57 | 0.00 | 0.00 | 0.00 | 0.00 | 1.18 | 0.54 | 0.00 | 0.20 | 0.00 | 0.22 | 0.00 | 0.00 |
| PI4KB | ENSG00000143393 | 0.00 | 2.80 | 0.21 | 1.09 | 0.00 | 0.65 | 0.00 | 0.00 | 0.26 | 0.40 | 0.00 | 0.81 | 0.00 | 0.74 | 0.39 | 0.56 | 2.07 | 0.43 | 0.00 | 1.47 | 1.15 | 0.00 | 0.20 | 0.00 | 0.00 | 1.66 | 0.54 | 0.00 | 0.20 | 0.00 | 1.55 | 1.82 | 0.00 |
| BGLAP | ENSG00000242252 | 0.00 | 0.76 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.43 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.43 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.22 | 0.00 | 0.00 |
| CRABP2 | ENSG00000143320 | 0.00 | 0.51 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.28 | 0.75 | 0.64 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.78 | 0.00 | 0.00 | 0.27 | 0.00 | 0.00 | 0.00 | 1.11 | 0.00 | 0.00 |
|
Showing page 233 |
first page | previous page | next page | last page |
Copyright © 2020 University of Pennsylvania. All Rights Reserved.