Mutation
The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.
Summary of mutation frequency of the PDGs in each cancer type
| Showing page 23 |
first page | previous page | next page | last page |
| HGNC Symbol | Ensembl Gene ID | ACC_Mut% | BLCA_Mut% | BRCA_Mut% | CESC_Mut% | CHOL_Mut% | COAD_Mut% | DLBC_Mut% | ESCA_Mut% | GBM_Mut% | HNSC_Mut% | KICH_Mut% | KIRC_Mut% | KIRP_Mut% | LAML_Mut% | LGG_Mut% | LIHC_Mut% | LUAD_Mut% | LUSC_Mut% | MESO_Mut% | OV_Mut% | PAAD_Mut% | PCPG_Mut% | PRAD_Mut% | READ_Mut% | SARC_Mut% | SKCM_Mut% | STAD_Mut% | TGCT_Mut% | THCA_Mut% | THYM_Mut% | UCEC_Mut% | UCS_Mut% | UVM_Mut% |
| ADORA2B | ENSG00000170425 | 0.00 | 0.25 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.55 | 0.26 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.28 | 0.19 | 0.00 | 0.00 | 0.49 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.95 | 0.00 | 0.00 | 0.00 | 0.00 | 0.67 | 0.00 | 0.00 |
| ADRA1B | ENSG00000170214 | 0.00 | 0.25 | 0.10 | 1.09 | 0.00 | 0.32 | 0.00 | 0.00 | 0.00 | 0.60 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 1.13 | 0.21 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 0.95 | 0.00 | 0.00 | 0.00 | 0.00 | 1.11 | 0.00 | 0.00 |
| CHRNE | ENSG00000108556 | 0.00 | 0.76 | 0.00 | 0.36 | 0.00 | 0.32 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 0.36 | 0.00 | 0.20 | 0.28 | 0.56 | 0.00 | 0.00 | 0.25 | 0.00 | 0.00 | 0.20 | 0.00 | 0.43 | 0.24 | 0.54 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| LOX | ENSG00000113083 | 1.11 | 0.76 | 0.10 | 0.00 | 0.00 | 0.32 | 2.70 | 0.00 | 0.00 | 0.20 | 1.54 | 0.00 | 0.36 | 0.00 | 0.00 | 0.56 | 0.94 | 0.43 | 1.23 | 0.00 | 0.57 | 0.00 | 0.20 | 0.00 | 0.00 | 0.95 | 0.27 | 0.00 | 0.00 | 0.00 | 0.22 | 0.00 | 0.00 |
| ERMP1 | ENSG00000099219 | 0.00 | 0.51 | 0.31 | 0.36 | 0.00 | 0.32 | 0.00 | 0.00 | 0.52 | 0.80 | 0.00 | 0.27 | 0.36 | 0.00 | 0.00 | 0.00 | 0.19 | 0.64 | 0.00 | 0.25 | 0.00 | 0.00 | 0.20 | 0.78 | 0.00 | 0.47 | 1.08 | 0.00 | 0.00 | 0.00 | 1.33 | 0.00 | 0.00 |
| PRSS35 | ENSG00000146250 | 1.11 | 0.76 | 0.52 | 0.36 | 0.00 | 0.97 | 0.00 | 1.10 | 0.77 | 0.20 | 0.00 | 0.00 | 0.00 | 0.00 | 0.39 | 0.28 | 1.32 | 2.79 | 0.00 | 0.49 | 1.15 | 0.00 | 0.00 | 0.00 | 0.00 | 2.84 | 0.81 | 0.00 | 0.00 | 0.00 | 1.33 | 0.00 | 0.00 |
| GABRB3 | ENSG00000166206 | 1.11 | 1.53 | 0.31 | 2.19 | 2.86 | 2.90 | 0.00 | 1.66 | 1.55 | 1.99 | 0.00 | 0.27 | 0.71 | 0.00 | 0.00 | 0.28 | 4.90 | 4.51 | 0.00 | 0.74 | 1.15 | 0.00 | 0.20 | 1.56 | 0.43 | 3.79 | 1.36 | 0.00 | 0.00 | 0.00 | 1.33 | 0.00 | 0.00 |
| SLC18A1 | ENSG00000036565 | 0.00 | 0.00 | 0.31 | 0.36 | 0.00 | 0.32 | 2.70 | 0.00 | 0.52 | 0.60 | 0.00 | 0.54 | 0.00 | 0.74 | 0.20 | 0.28 | 1.13 | 1.93 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 1.66 | 0.27 | 0.00 | 0.00 | 0.00 | 0.89 | 0.00 | 0.00 |
| MCAM | ENSG00000076706 | 0.00 | 1.78 | 0.21 | 0.00 | 0.00 | 0.65 | 0.00 | 0.00 | 0.52 | 0.20 | 0.00 | 0.54 | 0.71 | 0.00 | 0.00 | 0.00 | 1.32 | 1.07 | 0.00 | 1.47 | 0.00 | 0.00 | 0.00 | 1.56 | 0.43 | 0.95 | 0.81 | 0.00 | 0.00 | 0.00 | 0.67 | 1.82 | 0.00 |
| MFI2 | ENSG00000163975 | 0.00 | 1.02 | 0.83 | 1.09 | 0.00 | 0.65 | 0.00 | 1.10 | 0.00 | 1.20 | 0.00 | 0.27 | 0.00 | 0.00 | 0.39 | 0.00 | 0.94 | 1.50 | 1.23 | 0.25 | 0.00 | 0.00 | 0.41 | 0.00 | 0.43 | 0.71 | 0.27 | 0.00 | 0.00 | 0.00 | 1.55 | 0.00 | 0.00 |
| MSR1 | ENSG00000038945 | 1.11 | 0.76 | 0.10 | 0.73 | 0.00 | 0.65 | 0.00 | 1.66 | 1.55 | 0.80 | 0.00 | 1.36 | 0.36 | 0.00 | 0.20 | 0.00 | 1.51 | 3.00 | 0.00 | 0.74 | 0.00 | 0.56 | 0.00 | 1.56 | 0.00 | 7.35 | 4.07 | 0.00 | 0.00 | 0.00 | 0.67 | 0.00 | 1.25 |
| SLC39A8 | ENSG00000138821 | 0.00 | 0.51 | 0.00 | 0.00 | 0.00 | 0.65 | 0.00 | 1.10 | 0.00 | 0.60 | 0.00 | 0.00 | 0.36 | 0.00 | 0.00 | 1.11 | 0.56 | 0.43 | 0.00 | 0.25 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.71 | 0.54 | 0.00 | 0.00 | 0.00 | 0.89 | 0.00 | 0.00 |
| TGFB3 | ENSG00000119699 | 0.00 | 0.25 | 0.31 | 1.09 | 0.00 | 0.00 | 0.00 | 0.55 | 0.52 | 0.20 | 0.00 | 0.27 | 0.00 | 0.00 | 0.00 | 0.28 | 0.00 | 0.21 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.95 | 0.27 | 0.00 | 0.00 | 0.00 | 1.77 | 0.00 | 0.00 |
| NRXN3 | ENSG00000021645 | 0.00 | 2.04 | 0.72 | 2.55 | 2.86 | 2.90 | 5.41 | 1.66 | 1.03 | 2.99 | 0.00 | 0.27 | 0.36 | 0.74 | 0.39 | 1.39 | 6.59 | 5.36 | 0.00 | 1.23 | 0.57 | 0.56 | 1.22 | 1.56 | 0.43 | 8.53 | 3.79 | 0.00 | 0.20 | 0.00 | 2.88 | 0.00 | 0.00 |
| TNFRSF9 | ENSG00000049249 | 0.00 | 0.51 | 0.10 | 0.36 | 0.00 | 0.00 | 0.00 | 0.00 | 0.26 | 0.60 | 0.00 | 0.27 | 0.00 | 0.00 | 0.20 | 0.00 | 0.75 | 0.21 | 0.00 | 0.49 | 0.00 | 0.00 | 0.00 | 0.00 | 0.86 | 1.18 | 0.81 | 0.00 | 0.00 | 0.00 | 1.11 | 0.00 | 0.00 |
| ADRA1A | ENSG00000120907 | 0.00 | 1.27 | 0.31 | 1.09 | 0.00 | 0.00 | 0.00 | 0.55 | 0.00 | 1.00 | 0.00 | 0.27 | 0.00 | 0.74 | 0.00 | 0.00 | 0.56 | 1.93 | 0.00 | 0.25 | 1.72 | 0.00 | 0.20 | 3.13 | 0.00 | 2.84 | 1.90 | 0.00 | 0.20 | 0.00 | 1.33 | 0.00 | 0.00 |
| VCAM1 | ENSG00000162692 | 0.00 | 2.29 | 0.52 | 1.09 | 0.00 | 2.90 | 2.70 | 1.66 | 0.52 | 1.79 | 0.00 | 0.27 | 0.36 | 0.00 | 0.00 | 0.56 | 3.95 | 3.00 | 0.00 | 0.74 | 0.00 | 0.56 | 0.20 | 1.56 | 0.43 | 4.03 | 0.27 | 0.69 | 0.41 | 0.00 | 2.00 | 0.00 | 0.00 |
| TNFRSF4 | ENSG00000186827 | 0.00 | 0.25 | 0.00 | 0.00 | 0.00 | 0.32 | 0.00 | 0.55 | 0.52 | 0.40 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.56 | 0.38 | 0.21 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 0.00 | 0.27 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| TNFRSF8 | ENSG00000120949 | 0.00 | 1.53 | 0.41 | 1.09 | 0.00 | 0.00 | 2.70 | 1.66 | 1.29 | 0.40 | 0.00 | 0.00 | 0.36 | 0.74 | 0.20 | 0.28 | 0.94 | 0.86 | 0.00 | 0.74 | 0.00 | 0.00 | 0.41 | 0.00 | 0.86 | 4.74 | 1.08 | 0.00 | 0.00 | 0.00 | 0.67 | 0.00 | 1.25 |
| SLC7A5 | ENSG00000103257 | 0.00 | 0.76 | 0.10 | 0.36 | 0.00 | 0.32 | 0.00 | 0.00 | 0.77 | 0.40 | 0.00 | 0.27 | 0.36 | 0.00 | 0.39 | 0.28 | 0.56 | 0.43 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.78 | 0.43 | 0.24 | 0.81 | 0.00 | 0.20 | 0.00 | 0.89 | 0.00 | 0.00 |
|
Showing page 23 |
first page | previous page | next page | last page |
Copyright © 2020 University of Pennsylvania. All Rights Reserved.