Mutation
The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.
Summary of mutation frequency of the PDGs in each cancer type
| Showing page 229 |
first page | previous page | next page | last page |
| HGNC Symbol | Ensembl Gene ID | ACC_Mut% | BLCA_Mut% | BRCA_Mut% | CESC_Mut% | CHOL_Mut% | COAD_Mut% | DLBC_Mut% | ESCA_Mut% | GBM_Mut% | HNSC_Mut% | KICH_Mut% | KIRC_Mut% | KIRP_Mut% | LAML_Mut% | LGG_Mut% | LIHC_Mut% | LUAD_Mut% | LUSC_Mut% | MESO_Mut% | OV_Mut% | PAAD_Mut% | PCPG_Mut% | PRAD_Mut% | READ_Mut% | SARC_Mut% | SKCM_Mut% | STAD_Mut% | TGCT_Mut% | THCA_Mut% | THYM_Mut% | UCEC_Mut% | UCS_Mut% | UVM_Mut% |
| AMBN | ENSG00000178522 | 0.00 | 1.02 | 0.41 | 0.00 | 0.00 | 0.65 | 0.00 | 0.55 | 0.52 | 0.20 | 0.00 | 0.54 | 0.00 | 0.00 | 0.00 | 0.56 | 0.56 | 2.15 | 0.00 | 0.49 | 0.00 | 0.00 | 0.20 | 2.34 | 0.00 | 2.37 | 0.54 | 0.00 | 0.20 | 0.00 | 1.11 | 0.00 | 0.00 |
| CXCL6 | ENSG00000124875 | 0.00 | 0.25 | 0.21 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.26 | 0.20 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.28 | 0.56 | 0.21 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.47 | 0.00 | 0.69 | 0.00 | 0.00 | 0.22 | 0.00 | 0.00 |
| PF4V1 | ENSG00000109272 | 0.00 | 0.51 | 0.00 | 0.36 | 2.86 | 0.00 | 0.00 | 1.10 | 0.00 | 0.20 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.28 | 0.56 | 0.21 | 0.00 | 0.00 | 0.57 | 0.00 | 0.00 | 0.00 | 0.00 | 0.24 | 0.00 | 0.69 | 0.20 | 0.00 | 0.00 | 0.00 | 0.00 |
| CXCL3 | ENSG00000163734 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.67 | 0.00 | 0.00 |
| CXCL2 | ENSG00000081041 | 0.00 | 0.25 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.19 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.22 | 0.00 | 0.00 |
| ADH4 | ENSG00000198099 | 0.00 | 0.51 | 0.10 | 0.73 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.40 | 0.00 | 0.27 | 0.00 | 0.00 | 0.00 | 0.83 | 0.75 | 0.64 | 0.00 | 0.00 | 0.00 | 1.12 | 0.00 | 0.00 | 0.43 | 1.42 | 0.00 | 0.00 | 0.20 | 0.00 | 0.22 | 0.00 | 0.00 |
| ADH6 | ENSG00000172955 | 0.00 | 1.78 | 0.21 | 0.36 | 0.00 | 0.00 | 0.00 | 0.55 | 0.26 | 0.20 | 0.00 | 0.00 | 0.71 | 0.00 | 0.00 | 0.28 | 1.13 | 0.43 | 0.00 | 0.00 | 0.00 | 0.56 | 0.00 | 0.00 | 0.00 | 2.13 | 0.54 | 0.00 | 0.00 | 0.00 | 0.22 | 0.00 | 0.00 |
| ETNPPL | ENSG00000164089 | 0.00 | 1.53 | 0.31 | 0.36 | 0.00 | 0.65 | 0.00 | 1.66 | 0.52 | 0.80 | 0.00 | 0.54 | 0.00 | 0.00 | 0.20 | 0.00 | 1.88 | 1.72 | 0.00 | 0.25 | 0.57 | 0.00 | 0.41 | 0.00 | 0.00 | 1.18 | 0.54 | 0.00 | 0.00 | 0.00 | 0.67 | 0.00 | 0.00 |
| PDE5A | ENSG00000138735 | 0.00 | 1.78 | 0.31 | 0.73 | 0.00 | 0.65 | 0.00 | 0.00 | 0.00 | 1.20 | 0.00 | 0.54 | 0.71 | 0.74 | 0.00 | 0.28 | 1.13 | 1.72 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.56 | 0.00 | 2.13 | 0.54 | 0.00 | 0.20 | 0.00 | 0.44 | 0.00 | 0.00 |
| SPOCK3 | ENSG00000196104 | 0.00 | 1.27 | 0.10 | 0.36 | 0.00 | 0.97 | 0.00 | 1.10 | 1.03 | 0.80 | 1.54 | 0.00 | 0.36 | 0.00 | 0.20 | 0.56 | 1.51 | 2.58 | 0.00 | 0.25 | 0.57 | 0.00 | 0.00 | 2.34 | 0.43 | 6.64 | 0.54 | 0.00 | 0.20 | 0.00 | 1.55 | 0.00 | 0.00 |
| NEK1 | ENSG00000137601 | 0.00 | 1.27 | 0.31 | 1.46 | 0.00 | 0.32 | 5.41 | 0.55 | 0.52 | 1.59 | 0.00 | 0.54 | 0.36 | 0.00 | 0.39 | 0.00 | 1.88 | 0.21 | 0.00 | 1.47 | 0.00 | 0.00 | 0.20 | 0.78 | 0.86 | 1.90 | 0.81 | 0.69 | 0.00 | 0.00 | 2.44 | 0.00 | 0.00 |
| PLK2 | ENSG00000145632 | 0.00 | 1.02 | 0.83 | 0.36 | 0.00 | 0.00 | 0.00 | 0.00 | 0.77 | 0.80 | 0.00 | 0.00 | 0.00 | 0.74 | 0.00 | 0.00 | 1.13 | 0.21 | 0.00 | 0.49 | 0.57 | 0.00 | 0.00 | 0.00 | 0.00 | 1.42 | 0.54 | 0.00 | 0.41 | 0.00 | 1.77 | 0.00 | 0.00 |
| PGGT1B | ENSG00000164219 | 0.00 | 0.25 | 0.10 | 0.00 | 0.00 | 0.32 | 0.00 | 0.55 | 0.00 | 0.00 | 0.00 | 0.27 | 0.36 | 0.00 | 0.00 | 0.28 | 0.56 | 0.43 | 0.00 | 0.25 | 0.57 | 0.00 | 0.00 | 0.00 | 0.00 | 0.47 | 0.27 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| ADAMTS19 | ENSG00000145808 | 3.33 | 0.76 | 1.03 | 2.19 | 0.00 | 1.94 | 0.00 | 4.97 | 1.29 | 2.39 | 0.00 | 1.36 | 0.71 | 1.47 | 0.39 | 2.78 | 4.33 | 4.94 | 0.00 | 1.96 | 2.30 | 0.00 | 0.61 | 0.78 | 0.86 | 8.77 | 1.90 | 0.00 | 0.61 | 0.00 | 2.88 | 0.00 | 0.00 |
| LEAP2 | ENSG00000164406 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.28 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.24 | 0.00 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| SPINK9 | ENSG00000204909 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.28 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.67 | 0.00 | 0.00 |
| CSNK1A1 | ENSG00000113712 | 0.00 | 1.53 | 0.00 | 0.00 | 0.00 | 0.00 | 2.70 | 1.10 | 0.00 | 0.20 | 0.00 | 0.27 | 0.00 | 1.47 | 0.00 | 0.28 | 0.19 | 0.43 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.71 | 0.54 | 0.00 | 0.00 | 0.00 | 0.67 | 0.00 | 0.00 |
| IL12B | ENSG00000113302 | 0.00 | 0.76 | 0.10 | 1.09 | 0.00 | 0.00 | 0.00 | 0.00 | 0.52 | 0.40 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.56 | 0.38 | 1.29 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 0.95 | 0.27 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| PHYKPL | ENSG00000175309 | 0.00 | 0.25 | 0.31 | 0.36 | 0.00 | 0.00 | 0.00 | 1.10 | 0.00 | 0.20 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.28 | 0.38 | 0.21 | 0.00 | 0.49 | 0.57 | 0.00 | 0.00 | 0.00 | 0.43 | 0.71 | 0.00 | 0.00 | 0.00 | 0.00 | 0.22 | 0.00 | 0.00 |
| DUSP22 | ENSG00000112679 | 0.00 | 0.25 | 0.31 | 0.00 | 0.00 | 2.26 | 0.00 | 0.55 | 0.52 | 0.40 | 0.00 | 0.00 | 0.00 | 0.00 | 0.39 | 0.56 | 2.64 | 1.93 | 1.23 | 0.25 | 0.00 | 0.00 | 0.00 | 0.00 | 0.43 | 2.37 | 0.54 | 0.00 | 0.00 | 0.00 | 0.89 | 1.82 | 0.00 |
|
Showing page 229 |
first page | previous page | next page | last page |
Copyright © 2020 University of Pennsylvania. All Rights Reserved.