Mutation
The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.
Summary of mutation frequency of the PDGs in each cancer type
| Showing page 226 |
first page | previous page | next page | last page |
| HGNC Symbol | Ensembl Gene ID | ACC_Mut% | BLCA_Mut% | BRCA_Mut% | CESC_Mut% | CHOL_Mut% | COAD_Mut% | DLBC_Mut% | ESCA_Mut% | GBM_Mut% | HNSC_Mut% | KICH_Mut% | KIRC_Mut% | KIRP_Mut% | LAML_Mut% | LGG_Mut% | LIHC_Mut% | LUAD_Mut% | LUSC_Mut% | MESO_Mut% | OV_Mut% | PAAD_Mut% | PCPG_Mut% | PRAD_Mut% | READ_Mut% | SARC_Mut% | SKCM_Mut% | STAD_Mut% | TGCT_Mut% | THCA_Mut% | THYM_Mut% | UCEC_Mut% | UCS_Mut% | UVM_Mut% |
| CXCL17 | ENSG00000189377 | 0.00 | 0.51 | 0.21 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| SAE1 | ENSG00000142230 | 0.00 | 1.27 | 0.21 | 0.00 | 0.00 | 0.00 | 0.00 | 0.55 | 0.00 | 0.40 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.38 | 0.64 | 1.23 | 0.25 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.95 | 0.27 | 0.69 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| HSD17B14 | ENSG00000087076 | 0.00 | 0.25 | 0.00 | 0.36 | 0.00 | 0.32 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 1.07 | 0.00 | 0.00 | 0.00 | 0.19 | 0.64 | 0.00 | 0.25 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.47 | 0.00 | 0.00 | 0.00 | 0.00 | 0.89 | 0.00 | 0.00 |
| KLK6 | ENSG00000167755 | 0.00 | 0.76 | 0.10 | 0.00 | 0.00 | 1.29 | 0.00 | 0.00 | 1.03 | 0.40 | 0.00 | 0.81 | 0.00 | 0.74 | 0.00 | 1.11 | 0.94 | 0.64 | 0.00 | 0.25 | 0.00 | 0.00 | 0.41 | 0.00 | 0.00 | 2.37 | 0.00 | 0.00 | 0.00 | 0.00 | 0.67 | 0.00 | 0.00 |
| RDH13 | ENSG00000160439 | 0.00 | 0.25 | 0.10 | 0.36 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.36 | 0.00 | 0.00 | 0.00 | 0.19 | 0.43 | 0.00 | 0.49 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.69 | 0.00 | 0.00 | 1.33 | 0.00 | 0.00 |
| IL11 | ENSG00000095752 | 0.00 | 0.00 | 0.21 | 0.00 | 0.00 | 0.65 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.19 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.24 | 0.54 | 0.00 | 0.00 | 0.00 | 0.22 | 0.00 | 0.00 |
| AURKC | ENSG00000105146 | 0.00 | 1.02 | 0.10 | 0.00 | 0.00 | 1.29 | 0.00 | 0.55 | 0.26 | 1.20 | 0.00 | 0.00 | 0.00 | 0.74 | 0.00 | 0.00 | 0.75 | 0.64 | 0.00 | 0.49 | 0.00 | 0.56 | 0.00 | 2.34 | 0.00 | 0.95 | 0.81 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| KHK | ENSG00000138030 | 0.00 | 0.25 | 0.10 | 1.09 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.40 | 0.00 | 1.08 | 1.07 | 0.00 | 0.00 | 0.00 | 0.19 | 1.29 | 1.23 | 0.25 | 0.00 | 0.00 | 0.00 | 0.00 | 0.43 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.22 | 0.00 | 0.00 |
| CAD | ENSG00000084774 | 0.00 | 3.05 | 1.03 | 2.55 | 2.86 | 0.97 | 2.70 | 2.21 | 2.06 | 0.60 | 0.00 | 0.81 | 1.42 | 0.74 | 0.59 | 0.83 | 3.20 | 3.00 | 1.23 | 1.96 | 0.57 | 0.00 | 0.61 | 0.78 | 0.00 | 4.50 | 1.63 | 0.69 | 0.20 | 0.00 | 3.99 | 1.82 | 0.00 |
| REG1B | ENSG00000172023 | 0.00 | 1.02 | 0.31 | 0.73 | 0.00 | 0.32 | 0.00 | 0.55 | 0.26 | 1.39 | 0.00 | 0.27 | 0.00 | 0.00 | 0.20 | 0.28 | 3.77 | 4.72 | 0.00 | 0.25 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.66 | 1.36 | 0.00 | 0.00 | 0.00 | 0.22 | 0.00 | 0.00 |
| REG3A | ENSG00000172016 | 1.11 | 0.76 | 0.31 | 0.36 | 0.00 | 0.65 | 0.00 | 0.55 | 0.00 | 1.39 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 4.33 | 4.29 | 0.00 | 0.00 | 0.57 | 0.00 | 0.00 | 0.00 | 0.43 | 1.66 | 0.00 | 0.00 | 0.20 | 0.00 | 0.22 | 0.00 | 0.00 |
| MAP4K4 | ENSG00000071054 | 0.00 | 1.27 | 0.62 | 1.09 | 0.00 | 0.65 | 0.00 | 0.55 | 1.03 | 0.60 | 0.00 | 0.81 | 0.00 | 0.74 | 0.20 | 0.83 | 0.75 | 1.72 | 0.00 | 0.00 | 0.57 | 0.00 | 0.00 | 0.00 | 1.29 | 2.84 | 0.81 | 0.00 | 0.20 | 0.00 | 1.55 | 0.00 | 0.00 |
| BUB1 | ENSG00000169679 | 0.00 | 3.05 | 0.31 | 0.73 | 0.00 | 0.65 | 0.00 | 1.10 | 0.52 | 1.20 | 0.00 | 0.27 | 0.36 | 0.00 | 0.39 | 0.56 | 1.51 | 1.29 | 0.00 | 0.49 | 1.15 | 0.00 | 0.00 | 0.00 | 0.00 | 2.13 | 1.90 | 0.00 | 0.00 | 0.83 | 1.55 | 0.00 | 0.00 |
| INHBB | ENSG00000163083 | 0.00 | 0.51 | 0.10 | 0.36 | 0.00 | 0.32 | 0.00 | 0.55 | 0.00 | 0.40 | 0.00 | 0.00 | 0.00 | 0.74 | 0.00 | 0.00 | 0.75 | 0.43 | 0.00 | 0.25 | 0.57 | 0.00 | 0.00 | 1.56 | 0.00 | 1.90 | 0.27 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| CYP27C1 | ENSG00000186684 | 0.00 | 1.02 | 0.10 | 0.00 | 0.00 | 1.61 | 2.70 | 0.55 | 0.26 | 0.60 | 0.00 | 0.27 | 0.00 | 0.74 | 0.00 | 0.56 | 0.38 | 0.86 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.78 | 0.00 | 0.95 | 0.00 | 0.00 | 0.00 | 0.00 | 1.33 | 0.00 | 0.00 |
| GPD2 | ENSG00000115159 | 0.00 | 1.53 | 0.31 | 1.09 | 0.00 | 0.32 | 2.70 | 0.00 | 0.26 | 0.60 | 0.00 | 0.27 | 0.36 | 0.74 | 0.00 | 0.00 | 1.32 | 1.50 | 1.23 | 0.49 | 0.57 | 0.00 | 0.00 | 1.56 | 0.43 | 0.95 | 0.27 | 0.00 | 0.00 | 0.83 | 0.44 | 0.00 | 0.00 |
| PDE11A | ENSG00000128655 | 0.00 | 4.33 | 0.52 | 1.09 | 0.00 | 0.65 | 0.00 | 1.66 | 1.55 | 0.80 | 0.00 | 0.54 | 0.36 | 0.74 | 0.39 | 1.67 | 2.45 | 4.94 | 0.00 | 1.47 | 0.00 | 0.00 | 0.00 | 0.78 | 0.43 | 3.55 | 0.81 | 0.00 | 0.00 | 0.00 | 1.77 | 0.00 | 0.00 |
| CDK15 | ENSG00000138395 | 0.00 | 1.53 | 0.00 | 0.00 | 0.00 | 0.32 | 0.00 | 0.00 | 0.26 | 0.80 | 0.00 | 0.54 | 0.00 | 0.00 | 0.00 | 0.28 | 1.13 | 2.58 | 0.00 | 0.74 | 0.00 | 0.00 | 0.00 | 0.78 | 0.00 | 0.24 | 0.54 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| CPS1 | ENSG00000021826 | 0.00 | 2.54 | 1.55 | 0.36 | 0.00 | 2.26 | 2.70 | 4.42 | 1.55 | 2.39 | 0.00 | 1.08 | 1.07 | 0.00 | 0.39 | 2.50 | 9.79 | 11.37 | 0.00 | 1.96 | 0.57 | 0.00 | 0.61 | 0.78 | 0.86 | 5.21 | 3.79 | 0.00 | 0.20 | 0.00 | 2.44 | 0.00 | 0.00 |
| STK16 | ENSG00000115661 | 0.00 | 0.51 | 0.00 | 0.36 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.60 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.56 | 0.86 | 0.00 | 0.25 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.71 | 0.27 | 0.00 | 0.00 | 0.00 | 0.67 | 1.82 | 0.00 |
|
Showing page 226 |
first page | previous page | next page | last page |
Copyright © 2020 University of Pennsylvania. All Rights Reserved.