Mutation
The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.
Summary of mutation frequency of the PDGs in each cancer type
| Showing page 220 |
first page | previous page | next page | last page |
| HGNC Symbol | Ensembl Gene ID | ACC_Mut% | BLCA_Mut% | BRCA_Mut% | CESC_Mut% | CHOL_Mut% | COAD_Mut% | DLBC_Mut% | ESCA_Mut% | GBM_Mut% | HNSC_Mut% | KICH_Mut% | KIRC_Mut% | KIRP_Mut% | LAML_Mut% | LGG_Mut% | LIHC_Mut% | LUAD_Mut% | LUSC_Mut% | MESO_Mut% | OV_Mut% | PAAD_Mut% | PCPG_Mut% | PRAD_Mut% | READ_Mut% | SARC_Mut% | SKCM_Mut% | STAD_Mut% | TGCT_Mut% | THCA_Mut% | THYM_Mut% | UCEC_Mut% | UCS_Mut% | UVM_Mut% |
| CDC7 | ENSG00000097046 | 1.11 | 0.51 | 0.21 | 0.36 | 0.00 | 0.00 | 0.00 | 0.55 | 0.52 | 0.20 | 0.00 | 0.27 | 0.36 | 0.00 | 0.39 | 0.83 | 0.19 | 1.07 | 0.00 | 0.74 | 0.00 | 0.00 | 0.41 | 0.78 | 0.00 | 0.71 | 0.00 | 0.00 | 0.20 | 0.00 | 2.88 | 0.00 | 0.00 |
| HAO2 | ENSG00000116882 | 0.00 | 1.27 | 0.00 | 0.36 | 0.00 | 0.00 | 0.00 | 0.55 | 0.52 | 0.20 | 0.00 | 0.00 | 0.36 | 0.00 | 0.39 | 0.00 | 0.94 | 0.43 | 0.00 | 0.74 | 0.00 | 0.00 | 0.00 | 0.78 | 0.00 | 3.08 | 0.81 | 0.00 | 0.00 | 0.00 | 1.33 | 0.00 | 0.00 |
| PGLYRP3 | ENSG00000159527 | 0.00 | 0.25 | 0.62 | 0.00 | 0.00 | 0.97 | 0.00 | 0.55 | 0.00 | 0.00 | 0.00 | 0.81 | 0.71 | 0.00 | 0.20 | 0.28 | 1.13 | 0.86 | 0.00 | 0.74 | 0.00 | 0.00 | 0.20 | 0.00 | 0.86 | 1.90 | 0.81 | 0.00 | 0.00 | 0.00 | 0.89 | 0.00 | 0.00 |
| CLK2 | ENSG00000176444 | 1.11 | 2.29 | 0.31 | 1.09 | 0.00 | 0.32 | 0.00 | 0.00 | 0.00 | 1.99 | 0.00 | 0.27 | 0.71 | 0.00 | 0.00 | 0.83 | 1.13 | 0.43 | 0.00 | 0.98 | 0.57 | 0.56 | 0.00 | 0.78 | 0.00 | 2.13 | 0.54 | 0.00 | 0.00 | 0.00 | 1.77 | 0.00 | 0.00 |
| CRP | ENSG00000132693 | 0.00 | 0.51 | 0.21 | 0.00 | 0.00 | 0.32 | 0.00 | 0.55 | 0.26 | 0.40 | 0.00 | 0.27 | 0.00 | 0.00 | 0.00 | 0.56 | 0.56 | 1.29 | 0.00 | 0.25 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 2.61 | 0.27 | 0.00 | 0.20 | 0.00 | 0.22 | 0.00 | 0.00 |
| PPOX | ENSG00000143224 | 0.00 | 0.76 | 0.52 | 0.73 | 0.00 | 0.32 | 0.00 | 1.10 | 0.26 | 0.20 | 0.00 | 0.00 | 0.36 | 0.00 | 0.20 | 0.28 | 0.56 | 0.21 | 0.00 | 0.49 | 0.57 | 0.00 | 0.00 | 0.00 | 0.43 | 0.24 | 1.08 | 0.00 | 0.00 | 0.00 | 0.22 | 1.82 | 0.00 |
| XCL2 | ENSG00000143185 | 0.00 | 0.00 | 0.10 | 0.36 | 0.00 | 0.00 | 0.00 | 0.00 | 0.52 | 0.20 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.28 | 0.75 | 0.64 | 0.00 | 0.25 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.24 | 0.00 | 0.00 | 0.00 | 0.00 | 0.22 | 0.00 | 0.00 |
| XCL1 | ENSG00000143184 | 0.00 | 0.00 | 0.21 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.52 | 0.20 | 0.00 | 0.27 | 0.00 | 0.00 | 0.20 | 0.28 | 0.75 | 0.64 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| ABL2 | ENSG00000143322 | 0.00 | 2.04 | 0.83 | 1.09 | 0.00 | 1.29 | 0.00 | 0.00 | 0.77 | 1.59 | 0.00 | 0.81 | 0.71 | 0.00 | 0.20 | 0.56 | 1.69 | 2.36 | 0.00 | 0.98 | 0.00 | 0.00 | 0.00 | 0.78 | 0.43 | 3.08 | 1.63 | 0.00 | 0.20 | 0.00 | 2.22 | 0.00 | 0.00 |
| CTSE | ENSG00000196188 | 0.00 | 0.51 | 0.31 | 0.36 | 0.00 | 0.32 | 0.00 | 0.00 | 0.26 | 0.00 | 0.00 | 0.54 | 0.36 | 0.00 | 0.00 | 0.28 | 0.38 | 0.43 | 0.00 | 0.00 | 0.00 | 0.00 | 0.41 | 0.00 | 0.43 | 2.61 | 0.27 | 0.00 | 0.00 | 0.00 | 0.67 | 1.82 | 0.00 |
| NEK2 | ENSG00000117650 | 1.11 | 0.51 | 0.10 | 0.36 | 0.00 | 0.00 | 0.00 | 0.00 | 0.26 | 0.60 | 0.00 | 0.27 | 0.71 | 0.00 | 0.00 | 0.83 | 0.19 | 0.64 | 1.23 | 0.25 | 0.00 | 0.00 | 0.00 | 0.78 | 0.00 | 1.66 | 0.27 | 0.00 | 0.00 | 0.00 | 1.55 | 0.00 | 0.00 |
| IARS2 | ENSG00000067704 | 0.00 | 2.04 | 0.31 | 0.73 | 0.00 | 0.65 | 0.00 | 0.00 | 0.00 | 0.40 | 0.00 | 0.54 | 1.42 | 0.00 | 0.20 | 0.56 | 2.45 | 0.86 | 0.00 | 0.49 | 0.00 | 0.00 | 0.20 | 0.00 | 0.86 | 2.37 | 1.08 | 0.00 | 0.00 | 0.00 | 2.44 | 1.82 | 0.00 |
| CDC42BPA | ENSG00000143776 | 0.00 | 2.04 | 1.45 | 1.09 | 0.00 | 1.61 | 0.00 | 1.10 | 0.00 | 1.20 | 0.00 | 0.54 | 1.42 | 0.74 | 0.39 | 2.22 | 2.26 | 3.22 | 0.00 | 1.23 | 0.00 | 1.12 | 0.00 | 0.78 | 0.00 | 2.13 | 1.08 | 0.00 | 0.00 | 0.00 | 1.77 | 0.00 | 0.00 |
| CDK1 | ENSG00000170312 | 0.00 | 0.00 | 0.21 | 0.00 | 0.00 | 0.97 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 0.36 | 0.00 | 0.00 | 0.28 | 0.38 | 0.21 | 0.00 | 0.25 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.71 | 0.27 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| SRGN | ENSG00000122862 | 0.00 | 0.51 | 0.10 | 0.36 | 0.00 | 0.32 | 0.00 | 0.00 | 0.00 | 0.00 | 1.54 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.19 | 0.21 | 0.00 | 0.25 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.47 | 0.00 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| HKDC1 | ENSG00000156510 | 2.22 | 1.78 | 0.21 | 0.73 | 0.00 | 0.00 | 5.41 | 1.10 | 0.00 | 0.80 | 0.00 | 0.00 | 0.00 | 0.74 | 0.98 | 0.83 | 1.13 | 1.07 | 0.00 | 0.74 | 0.57 | 0.00 | 0.61 | 0.00 | 0.43 | 2.84 | 1.08 | 0.00 | 0.41 | 0.00 | 2.00 | 1.82 | 0.00 |
| SFTPD | ENSG00000133661 | 0.00 | 0.00 | 0.21 | 0.73 | 0.00 | 0.65 | 2.70 | 0.00 | 0.00 | 0.60 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.19 | 0.43 | 0.00 | 0.25 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 2.61 | 0.00 | 0.00 | 0.00 | 0.00 | 0.67 | 0.00 | 0.00 |
| CHUK | ENSG00000213341 | 0.00 | 1.02 | 0.31 | 0.73 | 0.00 | 1.61 | 0.00 | 1.10 | 0.26 | 1.00 | 1.54 | 0.27 | 0.00 | 0.74 | 0.00 | 1.67 | 1.32 | 0.86 | 0.00 | 0.74 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 0.47 | 0.27 | 0.00 | 0.00 | 0.00 | 1.11 | 0.00 | 0.00 |
| PNLIP | ENSG00000175535 | 1.11 | 1.27 | 0.31 | 0.36 | 0.00 | 0.65 | 0.00 | 0.00 | 0.26 | 0.80 | 0.00 | 1.08 | 0.00 | 0.00 | 0.00 | 0.28 | 2.82 | 4.51 | 0.00 | 0.98 | 0.57 | 0.00 | 0.61 | 1.56 | 0.00 | 1.90 | 0.81 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 1.25 |
| NPS | ENSG00000214285 | 0.00 | 0.51 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.55 | 0.00 | 0.20 | 0.00 | 0.00 | 0.36 | 0.00 | 0.00 | 0.28 | 0.56 | 1.07 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 0.95 | 0.00 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
|
Showing page 220 |
first page | previous page | next page | last page |
Copyright © 2020 University of Pennsylvania. All Rights Reserved.