Mutation
The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.
Summary of mutation frequency of the PDGs in each cancer type
| Showing page 207 |
first page | previous page | next page | last page |
| HGNC Symbol | Ensembl Gene ID | ACC_Mut% | BLCA_Mut% | BRCA_Mut% | CESC_Mut% | CHOL_Mut% | COAD_Mut% | DLBC_Mut% | ESCA_Mut% | GBM_Mut% | HNSC_Mut% | KICH_Mut% | KIRC_Mut% | KIRP_Mut% | LAML_Mut% | LGG_Mut% | LIHC_Mut% | LUAD_Mut% | LUSC_Mut% | MESO_Mut% | OV_Mut% | PAAD_Mut% | PCPG_Mut% | PRAD_Mut% | READ_Mut% | SARC_Mut% | SKCM_Mut% | STAD_Mut% | TGCT_Mut% | THCA_Mut% | THYM_Mut% | UCEC_Mut% | UCS_Mut% | UVM_Mut% |
| HSDL1 | ENSG00000103160 | 0.00 | 0.25 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.55 | 0.00 | 0.40 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.38 | 0.86 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.24 | 0.00 | 0.00 | 0.00 | 0.00 | 0.67 | 0.00 | 0.00 |
| CRISPLD2 | ENSG00000103196 | 0.00 | 0.51 | 0.10 | 0.36 | 0.00 | 0.00 | 0.00 | 0.00 | 0.26 | 0.20 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.28 | 0.94 | 0.86 | 0.00 | 0.49 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.95 | 0.27 | 0.00 | 0.41 | 0.00 | 0.67 | 0.00 | 1.25 |
| CDK10 | ENSG00000185324 | 0.00 | 0.51 | 0.31 | 1.46 | 0.00 | 0.32 | 0.00 | 0.55 | 0.00 | 0.20 | 0.00 | 0.00 | 0.71 | 0.00 | 0.20 | 0.00 | 0.38 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.78 | 0.00 | 0.24 | 0.54 | 0.00 | 0.00 | 0.00 | 0.67 | 1.82 | 0.00 |
| MAP2K3 | ENSG00000034152 | 1.11 | 1.27 | 0.31 | 0.36 | 0.00 | 0.00 | 5.41 | 0.55 | 1.03 | 0.80 | 0.00 | 0.00 | 0.71 | 0.00 | 0.20 | 0.56 | 1.69 | 1.29 | 1.23 | 0.25 | 0.00 | 0.00 | 0.00 | 0.78 | 0.00 | 2.37 | 1.08 | 0.00 | 0.00 | 0.00 | 1.33 | 0.00 | 1.25 |
| DHRS13 | ENSG00000167536 | 0.00 | 0.00 | 0.31 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.26 | 0.20 | 0.00 | 0.27 | 0.00 | 0.00 | 0.00 | 0.28 | 0.00 | 0.43 | 0.00 | 0.25 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 0.24 | 0.00 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| CCL4L2 | ENSG00000276070 | |||||||||||||||||||||||||||||||||
| TUBD1 | ENSG00000108423 | 0.00 | 1.27 | 0.41 | 1.46 | 2.86 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.27 | 0.00 | 0.00 | 0.20 | 0.28 | 0.94 | 0.21 | 0.00 | 0.25 | 0.00 | 0.00 | 0.20 | 1.56 | 0.00 | 0.95 | 0.54 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| SLC25A19 | ENSG00000125454 | 1.11 | 0.76 | 0.10 | 0.00 | 0.00 | 0.65 | 0.00 | 0.55 | 0.26 | 0.20 | 0.00 | 0.00 | 0.71 | 0.00 | 0.00 | 0.28 | 0.19 | 0.00 | 1.23 | 0.25 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.71 | 0.00 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| NPB | ENSG00000183979 | 0.00 | 0.51 | 0.00 | 0.00 | 0.00 | 0.32 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.28 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| DAPK3 | ENSG00000167657 | 0.00 | 0.51 | 0.00 | 0.73 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.60 | 0.00 | 0.27 | 0.00 | 0.00 | 0.20 | 0.00 | 0.38 | 0.43 | 0.00 | 0.49 | 0.00 | 0.00 | 0.00 | 2.34 | 0.00 | 0.47 | 1.08 | 0.00 | 0.00 | 0.00 | 1.11 | 0.00 | 0.00 |
| SLC25A42 | ENSG00000181035 | 0.00 | 0.76 | 0.00 | 0.73 | 0.00 | 0.32 | 0.00 | 0.00 | 0.00 | 0.60 | 0.00 | 0.27 | 0.71 | 0.00 | 0.00 | 0.28 | 0.19 | 0.21 | 0.00 | 0.25 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.71 | 0.27 | 0.69 | 0.00 | 0.00 | 0.44 | 1.82 | 0.00 |
| HAPLN4 | ENSG00000187664 | 0.00 | 0.51 | 0.10 | 0.36 | 0.00 | 0.97 | 0.00 | 1.66 | 0.00 | 0.80 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.13 | 1.07 | 0.00 | 0.49 | 0.00 | 0.56 | 0.20 | 0.00 | 0.43 | 0.95 | 1.08 | 0.00 | 0.00 | 0.00 | 0.67 | 0.00 | 0.00 |
| HAMP | ENSG00000105697 | 0.00 | 0.25 | 0.10 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.27 | 0.36 | 0.00 | 0.00 | 0.00 | 0.38 | 0.21 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.47 | 0.00 | 0.00 | 0.00 | 0.00 | 0.22 | 0.00 | 0.00 |
| MIA | ENSG00000261857 | 0.00 | 0.51 | 0.10 | 0.36 | 0.00 | 0.00 | 2.70 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.43 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.56 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| CYP2B6 | ENSG00000197408 | 2.22 | 1.53 | 0.52 | 1.46 | 0.00 | 0.00 | 0.00 | 0.55 | 1.29 | 0.80 | 0.00 | 0.27 | 0.00 | 0.00 | 0.20 | 0.56 | 1.32 | 1.93 | 0.00 | 0.74 | 0.00 | 0.00 | 0.61 | 0.00 | 0.00 | 3.55 | 0.27 | 0.00 | 0.00 | 0.83 | 1.77 | 0.00 | 0.00 |
| APOC1 | ENSG00000130208 | 0.00 | 0.51 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.28 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.24 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| NUCB1 | ENSG00000104805 | 0.00 | 1.53 | 0.00 | 0.36 | 0.00 | 0.65 | 0.00 | 1.10 | 0.26 | 0.60 | 0.00 | 0.27 | 0.36 | 0.00 | 0.00 | 0.00 | 0.19 | 1.29 | 0.00 | 0.49 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.71 | 0.27 | 0.00 | 0.00 | 0.00 | 1.33 | 0.00 | 0.00 |
| ALDH16A1 | ENSG00000161618 | 0.00 | 2.04 | 0.21 | 0.36 | 2.86 | 0.32 | 0.00 | 0.55 | 0.00 | 0.40 | 0.00 | 0.54 | 0.71 | 0.00 | 0.20 | 0.83 | 0.56 | 1.29 | 0.00 | 0.00 | 0.57 | 0.00 | 0.00 | 0.00 | 0.00 | 1.66 | 0.54 | 0.69 | 0.00 | 0.83 | 2.00 | 0.00 | 0.00 |
| SBK2 | ENSG00000187550 | 1.11 | 0.76 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.26 | 0.60 | 0.00 | 0.00 | 0.36 | 0.00 | 0.00 | 0.56 | 0.19 | 0.64 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 0.95 | 0.27 | 0.00 | 0.00 | 0.00 | 0.67 | 0.00 | 1.25 |
| SBK3 | ENSG00000231274 |
|
Showing page 207 |
first page | previous page | next page | last page |
Copyright © 2020 University of Pennsylvania. All Rights Reserved.