Mutation
The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.
Summary of mutation frequency of the PDGs in each cancer type
| Showing page 176 |
first page | previous page | next page | last page |
| HGNC Symbol | Ensembl Gene ID | ACC_Mut% | BLCA_Mut% | BRCA_Mut% | CESC_Mut% | CHOL_Mut% | COAD_Mut% | DLBC_Mut% | ESCA_Mut% | GBM_Mut% | HNSC_Mut% | KICH_Mut% | KIRC_Mut% | KIRP_Mut% | LAML_Mut% | LGG_Mut% | LIHC_Mut% | LUAD_Mut% | LUSC_Mut% | MESO_Mut% | OV_Mut% | PAAD_Mut% | PCPG_Mut% | PRAD_Mut% | READ_Mut% | SARC_Mut% | SKCM_Mut% | STAD_Mut% | TGCT_Mut% | THCA_Mut% | THYM_Mut% | UCEC_Mut% | UCS_Mut% | UVM_Mut% |
| PARP16 | ENSG00000138617 | 0.00 | 0.00 | 0.10 | 0.36 | 0.00 | 0.00 | 0.00 | 0.55 | 0.00 | 0.20 | 0.00 | 0.27 | 0.36 | 0.00 | 0.00 | 0.28 | 0.19 | 0.64 | 0.00 | 0.49 | 0.00 | 0.00 | 0.41 | 0.00 | 0.00 | 1.18 | 0.27 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| SEC11A | ENSG00000140612 | 0.00 | 0.25 | 0.00 | 0.36 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.27 | 0.00 | 0.00 | 0.00 | 0.00 | 0.19 | 0.64 | 0.00 | 0.49 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.22 | 1.82 | 0.00 |
| HSD3B7 | ENSG00000099377 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 2.70 | 1.10 | 0.00 | 0.20 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.28 | 0.94 | 0.00 | 0.00 | 0.25 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.18 | 0.54 | 0.00 | 0.20 | 0.00 | 0.89 | 0.00 | 0.00 |
| ST3GAL2 | ENSG00000157350 | 0.00 | 0.25 | 0.00 | 0.36 | 0.00 | 0.32 | 0.00 | 0.55 | 0.00 | 0.20 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.28 | 0.56 | 0.86 | 0.00 | 0.25 | 0.57 | 0.00 | 0.00 | 0.78 | 0.00 | 0.47 | 1.36 | 0.69 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| MBTPS1 | ENSG00000140943 | 2.22 | 2.80 | 0.52 | 1.46 | 0.00 | 0.97 | 0.00 | 0.00 | 0.26 | 1.59 | 1.54 | 0.27 | 0.36 | 0.74 | 0.00 | 0.56 | 1.13 | 1.93 | 0.00 | 1.23 | 0.57 | 0.00 | 0.41 | 0.78 | 0.00 | 1.18 | 0.54 | 0.00 | 0.20 | 0.00 | 2.66 | 0.00 | 0.00 |
| RHBDL3 | ENSG00000141314 | 0.00 | 1.53 | 0.10 | 0.00 | 0.00 | 0.65 | 0.00 | 0.00 | 0.26 | 0.40 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.56 | 0.56 | 0.21 | 0.00 | 0.25 | 0.57 | 0.00 | 0.20 | 1.56 | 0.00 | 0.24 | 0.54 | 0.00 | 0.00 | 0.00 | 0.89 | 1.82 | 0.00 |
| KCNH4 | ENSG00000089558 | 0.00 | 1.78 | 0.41 | 0.73 | 0.00 | 2.26 | 0.00 | 0.55 | 0.52 | 1.59 | 1.54 | 0.00 | 0.00 | 0.74 | 0.20 | 1.11 | 1.51 | 2.36 | 0.00 | 0.74 | 1.15 | 0.00 | 0.00 | 2.34 | 0.43 | 4.27 | 0.81 | 0.00 | 0.00 | 1.65 | 2.44 | 0.00 | 0.00 |
| SEC11C | ENSG00000166562 | 0.00 | 0.76 | 0.00 | 0.36 | 0.00 | 0.32 | 0.00 | 1.10 | 0.00 | 0.20 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.28 | 0.19 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.47 | 0.54 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| LMAN1 | ENSG00000074695 | 0.00 | 0.51 | 0.21 | 1.09 | 0.00 | 0.32 | 0.00 | 0.00 | 0.52 | 0.00 | 0.00 | 0.54 | 0.00 | 0.00 | 0.20 | 0.56 | 0.94 | 0.64 | 0.00 | 0.25 | 0.00 | 0.00 | 0.41 | 0.78 | 0.00 | 1.42 | 0.54 | 0.00 | 0.00 | 0.00 | 4.43 | 0.00 | 0.00 |
| BCL2 | ENSG00000171791 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 2.70 | 0.00 | 0.52 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.28 | 0.75 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.71 | 0.00 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| CYP4F8 | ENSG00000186526 | |||||||||||||||||||||||||||||||||
| CPT1C | ENSG00000169169 | 0.00 | 2.29 | 0.52 | 0.36 | 0.00 | 0.32 | 0.00 | 0.55 | 0.77 | 1.00 | 0.00 | 0.00 | 0.36 | 0.00 | 0.00 | 0.56 | 2.26 | 1.29 | 0.00 | 0.74 | 0.00 | 0.56 | 0.61 | 2.34 | 0.00 | 3.55 | 0.54 | 0.00 | 0.20 | 0.00 | 1.11 | 0.00 | 0.00 |
| HTRA2 | ENSG00000115317 | 0.00 | 1.27 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.26 | 0.60 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.56 | 0.19 | 1.50 | 0.00 | 0.49 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 0.24 | 0.54 | 0.00 | 0.20 | 0.00 | 1.55 | 0.00 | 0.00 |
| CHST10 | ENSG00000115526 | 0.00 | 0.00 | 0.00 | 0.73 | 0.00 | 1.29 | 0.00 | 0.55 | 0.00 | 0.80 | 0.00 | 0.27 | 0.00 | 0.00 | 0.00 | 1.11 | 0.38 | 1.29 | 0.00 | 0.49 | 0.00 | 0.00 | 0.00 | 0.78 | 0.86 | 1.18 | 0.54 | 0.00 | 0.20 | 0.83 | 0.89 | 0.00 | 0.00 |
| SMPD4 | ENSG00000136699 | 1.11 | 1.78 | 0.10 | 0.73 | 0.00 | 0.32 | 0.00 | 0.55 | 0.52 | 0.40 | 0.00 | 0.00 | 1.07 | 0.00 | 0.20 | 0.83 | 1.69 | 3.65 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 1.18 | 0.54 | 0.69 | 0.20 | 0.00 | 2.22 | 0.00 | 0.00 |
| UGT1A6 | ENSG00000167165 | 0.00 | 0.51 | 0.31 | 0.73 | 0.00 | 0.00 | 0.00 | 1.10 | 0.52 | 0.40 | 0.00 | 0.27 | 0.36 | 0.00 | 0.20 | 0.00 | 0.75 | 0.43 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.66 | 0.27 | 0.00 | 0.00 | 0.00 | 0.22 | 1.82 | 0.00 |
| ENTPD6 | ENSG00000197586 | 0.00 | 0.25 | 0.21 | 1.09 | 0.00 | 0.32 | 0.00 | 1.10 | 0.00 | 0.00 | 0.00 | 0.00 | 0.71 | 0.74 | 0.39 | 0.28 | 0.94 | 1.07 | 0.00 | 0.25 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 1.18 | 1.08 | 0.00 | 0.00 | 0.00 | 1.55 | 0.00 | 0.00 |
| ABHD12 | ENSG00000100997 | 0.00 | 1.02 | 0.10 | 0.00 | 0.00 | 0.32 | 0.00 | 0.55 | 0.00 | 0.40 | 0.00 | 0.27 | 0.36 | 0.00 | 0.00 | 0.56 | 0.19 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.78 | 0.00 | 0.71 | 0.00 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| BPI | ENSG00000101425 | 0.00 | 0.51 | 0.31 | 0.73 | 0.00 | 0.00 | 0.00 | 0.00 | 0.52 | 1.00 | 0.00 | 0.27 | 0.00 | 0.00 | 0.20 | 0.00 | 2.07 | 1.29 | 0.00 | 0.98 | 0.00 | 0.00 | 0.20 | 0.78 | 0.00 | 1.66 | 0.27 | 0.00 | 0.20 | 0.00 | 0.67 | 0.00 | 0.00 |
| TMPRSS3 | ENSG00000160183 | 0.00 | 0.00 | 0.21 | 0.36 | 0.00 | 0.97 | 0.00 | 0.00 | 0.00 | 0.60 | 0.00 | 0.27 | 0.36 | 0.00 | 0.20 | 0.83 | 0.75 | 0.64 | 1.23 | 0.25 | 0.57 | 0.00 | 0.00 | 0.00 | 0.86 | 3.08 | 0.27 | 0.00 | 0.00 | 0.00 | 0.67 | 0.00 | 0.00 |
|
Showing page 176 |
first page | previous page | next page | last page |
Copyright © 2020 University of Pennsylvania. All Rights Reserved.