Mutation
The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.
Summary of mutation frequency of the PDGs in each cancer type
| Showing page 175 |
first page | previous page | next page | last page |
| HGNC Symbol | Ensembl Gene ID | ACC_Mut% | BLCA_Mut% | BRCA_Mut% | CESC_Mut% | CHOL_Mut% | COAD_Mut% | DLBC_Mut% | ESCA_Mut% | GBM_Mut% | HNSC_Mut% | KICH_Mut% | KIRC_Mut% | KIRP_Mut% | LAML_Mut% | LGG_Mut% | LIHC_Mut% | LUAD_Mut% | LUSC_Mut% | MESO_Mut% | OV_Mut% | PAAD_Mut% | PCPG_Mut% | PRAD_Mut% | READ_Mut% | SARC_Mut% | SKCM_Mut% | STAD_Mut% | TGCT_Mut% | THCA_Mut% | THYM_Mut% | UCEC_Mut% | UCS_Mut% | UVM_Mut% |
| SLC13A1 | ENSG00000081800 | 1.11 | 1.27 | 0.52 | 1.09 | 0.00 | 0.97 | 0.00 | 1.10 | 0.00 | 1.39 | 0.00 | 0.27 | 0.71 | 0.00 | 0.39 | 0.56 | 1.13 | 3.86 | 0.00 | 1.23 | 0.00 | 0.00 | 0.00 | 0.78 | 0.43 | 2.84 | 1.08 | 0.00 | 0.20 | 0.83 | 1.77 | 0.00 | 1.25 |
| DNAJC16 | ENSG00000116138 | 0.00 | 1.78 | 0.31 | 1.09 | 0.00 | 0.00 | 0.00 | 0.00 | 0.52 | 0.00 | 0.00 | 0.81 | 1.07 | 0.00 | 0.20 | 0.56 | 0.19 | 0.00 | 0.00 | 0.25 | 0.00 | 0.00 | 0.20 | 0.78 | 0.00 | 1.66 | 0.00 | 0.00 | 0.20 | 0.00 | 0.67 | 0.00 | 0.00 |
| CLCNKA | ENSG00000186510 | 0.00 | 1.27 | 0.21 | 0.73 | 0.00 | 0.32 | 0.00 | 0.55 | 0.52 | 1.79 | 0.00 | 0.27 | 0.00 | 0.00 | 0.20 | 0.28 | 0.75 | 0.64 | 0.00 | 0.25 | 0.00 | 0.00 | 0.00 | 0.00 | 0.43 | 1.66 | 0.81 | 0.69 | 0.00 | 0.00 | 0.44 | 3.64 | 0.00 |
| ST3GAL3 | ENSG00000126091 | 0.00 | 0.76 | 0.62 | 0.73 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.60 | 0.00 | 0.27 | 0.00 | 0.74 | 0.39 | 0.00 | 0.56 | 0.21 | 0.00 | 0.74 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 1.25 |
| CYP4X1 | ENSG00000186377 | 0.00 | 1.53 | 0.31 | 0.36 | 0.00 | 0.65 | 0.00 | 0.55 | 0.52 | 0.40 | 0.00 | 0.27 | 0.36 | 0.00 | 0.00 | 0.00 | 0.38 | 0.21 | 1.23 | 0.49 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 4.74 | 0.81 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| CYP4Z1 | ENSG00000186160 | 0.00 | 1.02 | 0.31 | 0.73 | 0.00 | 0.65 | 0.00 | 0.00 | 0.52 | 0.60 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.28 | 0.38 | 0.43 | 0.00 | 0.74 | 0.00 | 0.00 | 0.41 | 1.56 | 0.43 | 5.69 | 0.54 | 0.00 | 0.00 | 0.00 | 0.89 | 1.82 | 0.00 |
| PIGK | ENSG00000142892 | 0.00 | 0.51 | 0.00 | 1.09 | 0.00 | 0.65 | 0.00 | 1.10 | 0.00 | 1.00 | 0.00 | 0.27 | 0.36 | 0.00 | 0.00 | 0.00 | 0.56 | 1.29 | 0.00 | 0.49 | 0.00 | 0.00 | 0.00 | 0.78 | 0.00 | 1.42 | 0.00 | 0.00 | 0.00 | 0.00 | 1.55 | 0.00 | 0.00 |
| FRRS1 | ENSG00000156869 | 0.00 | 1.02 | 0.41 | 0.00 | 0.00 | 0.00 | 0.00 | 1.10 | 0.26 | 0.20 | 0.00 | 0.00 | 0.71 | 0.74 | 0.20 | 0.56 | 0.38 | 1.29 | 1.23 | 0.25 | 0.00 | 0.00 | 0.00 | 0.00 | 0.43 | 1.42 | 0.27 | 0.00 | 0.20 | 0.00 | 0.44 | 1.82 | 0.00 |
| HSD3B2 | ENSG00000203859 | 0.00 | 0.76 | 0.62 | 1.09 | 0.00 | 0.00 | 0.00 | 1.10 | 0.26 | 0.40 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.69 | 1.07 | 0.00 | 0.49 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 2.84 | 0.27 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| FMO4 | ENSG00000076258 | 0.00 | 1.78 | 0.21 | 0.73 | 0.00 | 0.32 | 0.00 | 1.66 | 0.00 | 1.39 | 0.00 | 0.00 | 0.71 | 0.00 | 0.20 | 0.28 | 1.51 | 1.07 | 0.00 | 0.74 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 1.90 | 1.36 | 0.00 | 0.00 | 0.00 | 1.77 | 0.00 | 0.00 |
| YME1L1 | ENSG00000136758 | 0.00 | 2.80 | 0.52 | 0.36 | 0.00 | 1.29 | 0.00 | 0.55 | 0.52 | 0.80 | 0.00 | 1.08 | 0.00 | 0.00 | 0.78 | 0.56 | 1.13 | 1.07 | 0.00 | 0.25 | 0.00 | 0.00 | 0.00 | 0.78 | 0.43 | 1.42 | 0.27 | 0.00 | 0.00 | 0.83 | 0.67 | 1.82 | 0.00 |
| SGPL1 | ENSG00000166224 | 0.00 | 1.53 | 0.31 | 0.73 | 0.00 | 0.32 | 0.00 | 0.00 | 0.52 | 0.60 | 0.00 | 0.54 | 0.00 | 0.74 | 0.00 | 0.56 | 0.56 | 1.07 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.43 | 0.24 | 0.54 | 0.00 | 0.00 | 0.00 | 0.67 | 0.00 | 0.00 |
| TMX2 | ENSG00000213593 | 0.00 | 1.02 | 0.00 | 0.00 | 0.00 | 0.32 | 0.00 | 0.55 | 0.52 | 0.00 | 0.00 | 0.27 | 1.07 | 0.00 | 0.00 | 0.28 | 0.56 | 0.21 | 0.00 | 0.25 | 0.00 | 0.00 | 0.20 | 0.00 | 0.43 | 0.47 | 0.27 | 0.00 | 0.00 | 0.00 | 0.67 | 0.00 | 0.00 |
| RCE1 | ENSG00000173653 | 0.00 | 0.25 | 0.21 | 0.36 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.60 | 0.00 | 0.27 | 0.00 | 0.00 | 0.20 | 0.00 | 0.19 | 0.64 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.24 | 0.00 | 0.00 | 0.00 | 0.00 | 0.89 | 0.00 | 0.00 |
| CPT1A | ENSG00000110090 | 0.00 | 1.27 | 0.72 | 1.46 | 0.00 | 0.32 | 0.00 | 0.55 | 0.52 | 1.00 | 0.00 | 0.27 | 0.36 | 0.00 | 0.00 | 0.56 | 1.32 | 1.72 | 0.00 | 1.23 | 0.00 | 0.00 | 0.20 | 2.34 | 0.43 | 2.13 | 0.54 | 0.69 | 0.61 | 0.00 | 1.77 | 0.00 | 0.00 |
| LRTOMT | ENSG00000184154 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.10 | 0.00 | 0.00 | 0.00 | 0.27 | 0.00 | 0.00 | 0.00 | 0.83 | 0.00 | 0.00 | 0.00 | 0.25 | 0.00 | 0.00 | 0.00 | 0.00 | 0.86 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| PCSK7 | ENSG00000160613 | 1.11 | 1.02 | 0.21 | 1.09 | 0.00 | 0.65 | 0.00 | 0.55 | 0.26 | 0.40 | 0.00 | 0.00 | 0.36 | 0.00 | 0.20 | 1.11 | 1.51 | 1.07 | 0.00 | 0.49 | 0.00 | 0.56 | 0.00 | 0.78 | 0.00 | 1.42 | 0.81 | 0.00 | 0.41 | 0.83 | 1.33 | 0.00 | 2.50 |
| TMPRSS4 | ENSG00000137648 | 1.11 | 1.02 | 0.31 | 0.00 | 0.00 | 0.32 | 0.00 | 1.10 | 0.52 | 0.00 | 0.00 | 0.00 | 0.36 | 1.47 | 0.00 | 0.00 | 0.19 | 0.21 | 0.00 | 0.25 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.66 | 0.27 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| SHISA2 | ENSG00000180730 | 0.00 | 0.25 | 0.10 | 0.00 | 0.00 | 0.65 | 0.00 | 0.00 | 0.26 | 0.00 | 0.00 | 0.00 | 0.36 | 0.00 | 0.00 | 0.00 | 0.75 | 0.43 | 0.00 | 0.25 | 0.00 | 0.56 | 0.00 | 0.00 | 0.00 | 1.42 | 0.54 | 0.00 | 0.00 | 0.00 | 0.67 | 0.00 | 0.00 |
| CATSPER2 | ENSG00000166762 | 0.00 | 1.27 | 0.41 | 0.36 | 0.00 | 0.00 | 0.00 | 1.10 | 0.26 | 1.39 | 0.00 | 0.27 | 0.36 | 0.00 | 0.00 | 0.28 | 0.38 | 1.29 | 0.00 | 0.74 | 0.00 | 0.00 | 0.00 | 0.78 | 0.43 | 1.66 | 0.81 | 0.00 | 0.00 | 0.00 | 0.89 | 0.00 | 0.00 |
|
Showing page 175 |
first page | previous page | next page | last page |
Copyright © 2020 University of Pennsylvania. All Rights Reserved.