Mutation
The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.
Summary of mutation frequency of the PDGs in each cancer type
| Showing page 170 |
first page | previous page | next page | last page |
| HGNC Symbol | Ensembl Gene ID | ACC_Mut% | BLCA_Mut% | BRCA_Mut% | CESC_Mut% | CHOL_Mut% | COAD_Mut% | DLBC_Mut% | ESCA_Mut% | GBM_Mut% | HNSC_Mut% | KICH_Mut% | KIRC_Mut% | KIRP_Mut% | LAML_Mut% | LGG_Mut% | LIHC_Mut% | LUAD_Mut% | LUSC_Mut% | MESO_Mut% | OV_Mut% | PAAD_Mut% | PCPG_Mut% | PRAD_Mut% | READ_Mut% | SARC_Mut% | SKCM_Mut% | STAD_Mut% | TGCT_Mut% | THCA_Mut% | THYM_Mut% | UCEC_Mut% | UCS_Mut% | UVM_Mut% |
| IGLV1-44 | ENSG00000211651 | 0.00 | 0.25 | 0.00 | 0.36 | 0.00 | 0.32 | 2.70 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.28 | 0.38 | 1.29 | 0.00 | 0.49 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.24 | 0.27 | 0.00 | 0.00 | 0.00 | 0.22 | 0.00 | 0.00 |
| IGLV7-43 | ENSG00000211652 | 0.00 | 0.51 | 0.00 | 0.00 | 0.00 | 0.32 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.56 | 0.43 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.24 | 0.00 | 0.00 | 0.00 | 0.00 | 0.22 | 0.00 | 0.00 |
| IGLV1-40 | ENSG00000211653 | 0.00 | 0.25 | 0.21 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.56 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.24 | 0.54 | 0.00 | 0.00 | 0.00 | 0.22 | 0.00 | 0.00 |
| PRAME | ENSG00000185686 | 0.00 | 1.27 | 0.41 | 0.00 | 0.00 | 0.65 | 0.00 | 0.00 | 1.55 | 0.60 | 0.00 | 0.27 | 0.00 | 0.00 | 0.00 | 0.56 | 1.88 | 2.58 | 0.00 | 0.25 | 0.57 | 0.56 | 0.00 | 0.78 | 0.43 | 2.61 | 0.00 | 0.00 | 0.00 | 0.00 | 1.11 | 0.00 | 0.00 |
| GGTLC2 | ENSG00000100121 | 0.00 | 0.76 | 0.21 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.52 | 0.20 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.28 | 0.19 | 0.21 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.24 | 0.27 | 0.00 | 0.00 | 0.00 | 0.67 | 0.00 | 0.00 |
| IGLV3-27 | ENSG00000211658 | 0.00 | 0.51 | 0.00 | 0.36 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.74 | 0.00 | 0.28 | 0.75 | 0.21 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 1.56 | 0.43 | 0.24 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| IGLV3-25 | ENSG00000211659 | 0.00 | 0.00 | 0.00 | 0.36 | 0.00 | 0.00 | 8.11 | 0.00 | 0.26 | 0.20 | 0.00 | 0.27 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 0.43 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.24 | 0.54 | 0.00 | 0.00 | 0.00 | 0.67 | 0.00 | 0.00 |
| IGLV2-23 | ENSG00000211660 | 0.00 | 0.00 | 0.21 | 0.00 | 0.00 | 0.32 | 5.41 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.28 | 0.75 | 0.21 | 1.23 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.18 | 0.00 | 0.00 | 0.00 | 0.00 | 0.22 | 0.00 | 0.00 |
| IGLV2-11 | ENSG00000211668 | 0.00 | 0.51 | 0.00 | 0.36 | 0.00 | 0.00 | 0.00 | 0.00 | 0.26 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.38 | 0.86 | 0.00 | 0.25 | 0.57 | 0.00 | 0.00 | 0.00 | 0.00 | 0.71 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| IGLC2 | ENSG00000211677 | 0.00 | 0.25 | 0.00 | 0.00 | 0.00 | 0.32 | 16.22 | 0.00 | 0.00 | 0.00 | 0.00 | 0.27 | 0.00 | 0.00 | 0.00 | 0.00 | 0.19 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.24 | 0.27 | 0.00 | 0.00 | 0.00 | 0.22 | 0.00 | 0.00 |
| EWSR1 | ENSG00000182944 | 0.00 | 1.27 | 0.52 | 0.00 | 0.00 | 0.65 | 0.00 | 1.10 | 0.52 | 0.80 | 0.00 | 0.27 | 0.00 | 0.00 | 0.20 | 0.56 | 0.94 | 0.86 | 0.00 | 0.98 | 0.00 | 0.00 | 0.61 | 0.78 | 0.43 | 1.18 | 0.27 | 0.00 | 0.00 | 0.00 | 2.00 | 1.82 | 1.25 |
| TWF2 | ENSG00000247596 | 0.00 | 0.25 | 0.21 | 0.36 | 0.00 | 0.65 | 0.00 | 0.00 | 0.00 | 0.80 | 0.00 | 0.27 | 0.71 | 0.00 | 0.00 | 0.00 | 0.00 | 0.43 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.95 | 0.27 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 1.25 |
| ADH1A | ENSG00000187758 | 0.00 | 0.76 | 0.10 | 0.00 | 0.00 | 0.65 | 0.00 | 0.00 | 0.77 | 0.40 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.28 | 0.94 | 0.21 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.78 | 0.00 | 4.27 | 0.54 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| ADH1C | ENSG00000248144 | 0.00 | 0.76 | 0.62 | 0.36 | 0.00 | 0.32 | 0.00 | 1.10 | 0.77 | 0.60 | 0.00 | 0.00 | 0.00 | 0.00 | 0.59 | 0.28 | 1.32 | 0.86 | 0.00 | 0.25 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 7.35 | 0.54 | 0.00 | 0.00 | 0.00 | 1.33 | 0.00 | 0.00 |
| ADH7 | ENSG00000196344 | 1.11 | 1.02 | 0.21 | 0.36 | 0.00 | 0.32 | 0.00 | 0.55 | 0.26 | 0.40 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 1.51 | 0.43 | 0.00 | 0.25 | 0.00 | 0.00 | 0.00 | 0.00 | 0.86 | 2.13 | 0.27 | 0.00 | 0.41 | 0.00 | 0.22 | 0.00 | 0.00 |
| FABP2 | ENSG00000145384 | 1.11 | 0.25 | 0.00 | 0.00 | 0.00 | 0.65 | 0.00 | 0.00 | 0.00 | 0.40 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.28 | 0.19 | 0.21 | 0.00 | 0.25 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 2.13 | 0.27 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| PDZD2 | ENSG00000133401 | 1.11 | 4.58 | 1.65 | 1.82 | 0.00 | 2.58 | 0.00 | 6.08 | 1.03 | 3.98 | 1.54 | 1.90 | 1.07 | 0.74 | 0.59 | 1.67 | 3.20 | 7.73 | 2.47 | 2.21 | 0.57 | 0.00 | 0.81 | 4.69 | 1.72 | 11.14 | 3.25 | 0.00 | 1.02 | 0.00 | 4.88 | 0.00 | 1.25 |
| C7 | ENSG00000112936 | 1.11 | 1.02 | 0.72 | 0.36 | 0.00 | 0.32 | 2.70 | 2.21 | 0.52 | 1.79 | 0.00 | 0.81 | 0.36 | 0.00 | 0.59 | 0.56 | 5.65 | 5.36 | 0.00 | 0.98 | 0.57 | 0.00 | 0.00 | 1.56 | 0.86 | 10.43 | 0.54 | 0.00 | 0.41 | 0.00 | 1.77 | 0.00 | 0.00 |
| FARS2 | ENSG00000145982 | 0.00 | 0.25 | 0.10 | 0.73 | 0.00 | 0.32 | 0.00 | 0.00 | 0.26 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.39 | 0.28 | 0.94 | 0.21 | 0.00 | 1.23 | 0.57 | 0.00 | 0.41 | 1.56 | 0.00 | 1.66 | 0.54 | 0.00 | 0.00 | 0.00 | 0.67 | 0.00 | 0.00 |
| ME1 | ENSG00000065833 | 0.00 | 1.27 | 0.00 | 0.00 | 2.86 | 0.97 | 2.70 | 0.55 | 0.52 | 0.40 | 0.00 | 0.27 | 0.00 | 0.00 | 0.00 | 0.28 | 0.75 | 0.86 | 0.00 | 0.25 | 0.00 | 0.00 | 0.41 | 0.78 | 0.43 | 5.45 | 0.00 | 0.69 | 0.20 | 0.00 | 1.77 | 0.00 | 0.00 |
|
Showing page 170 |
first page | previous page | next page | last page |
Copyright © 2020 University of Pennsylvania. All Rights Reserved.