Mutation
The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.
Summary of mutation frequency of the PDGs in each cancer type
| Showing page 156 |
first page | previous page | next page | last page |
| HGNC Symbol | Ensembl Gene ID | ACC_Mut% | BLCA_Mut% | BRCA_Mut% | CESC_Mut% | CHOL_Mut% | COAD_Mut% | DLBC_Mut% | ESCA_Mut% | GBM_Mut% | HNSC_Mut% | KICH_Mut% | KIRC_Mut% | KIRP_Mut% | LAML_Mut% | LGG_Mut% | LIHC_Mut% | LUAD_Mut% | LUSC_Mut% | MESO_Mut% | OV_Mut% | PAAD_Mut% | PCPG_Mut% | PRAD_Mut% | READ_Mut% | SARC_Mut% | SKCM_Mut% | STAD_Mut% | TGCT_Mut% | THCA_Mut% | THYM_Mut% | UCEC_Mut% | UCS_Mut% | UVM_Mut% |
| ADM2 | ENSG00000128165 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.26 | 0.40 | 0.00 | 0.27 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.27 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| COL7A1 | ENSG00000114270 | 1.11 | 6.36 | 1.34 | 1.82 | 5.71 | 3.23 | 2.70 | 2.76 | 0.77 | 1.59 | 0.00 | 1.08 | 0.36 | 0.74 | 0.98 | 2.50 | 6.59 | 3.86 | 2.47 | 1.96 | 0.00 | 0.00 | 0.81 | 3.91 | 0.86 | 12.32 | 2.44 | 0.00 | 0.20 | 0.00 | 6.21 | 3.64 | 0.00 |
| ADAMTS9 | ENSG00000163638 | 1.11 | 5.60 | 1.03 | 1.09 | 0.00 | 2.90 | 2.70 | 1.10 | 0.52 | 2.39 | 0.00 | 0.81 | 0.36 | 0.00 | 1.18 | 2.50 | 3.39 | 3.00 | 1.23 | 0.98 | 1.15 | 0.00 | 0.61 | 0.00 | 0.43 | 6.64 | 2.44 | 0.00 | 0.20 | 0.83 | 3.33 | 0.00 | 0.00 |
| COL6A6 | ENSG00000206384 | 1.11 | 6.87 | 1.76 | 2.55 | 2.86 | 5.16 | 0.00 | 3.87 | 1.80 | 4.58 | 0.00 | 2.98 | 1.42 | 0.74 | 0.39 | 4.44 | 5.65 | 8.80 | 1.23 | 2.45 | 1.15 | 0.00 | 0.41 | 4.69 | 0.86 | 10.43 | 3.79 | 0.00 | 0.61 | 1.65 | 3.77 | 3.64 | 0.00 |
| CPZ | ENSG00000109625 | 0.00 | 1.02 | 0.41 | 1.09 | 0.00 | 0.97 | 2.70 | 1.10 | 0.52 | 0.80 | 0.00 | 0.27 | 0.00 | 0.00 | 0.20 | 0.56 | 3.20 | 3.65 | 0.00 | 0.98 | 0.00 | 0.56 | 0.00 | 1.56 | 0.43 | 3.79 | 0.81 | 0.69 | 0.20 | 0.00 | 1.55 | 0.00 | 0.00 |
| SOD3 | ENSG00000109610 | 0.00 | 0.25 | 0.00 | 0.00 | 0.00 | 0.00 | 2.70 | 0.00 | 0.00 | 0.60 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.19 | 0.21 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| CSN1S1 | ENSG00000126545 | 1.11 | 0.25 | 0.21 | 0.00 | 0.00 | 0.65 | 0.00 | 0.55 | 0.00 | 0.20 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.28 | 0.75 | 0.00 | 0.00 | 0.25 | 0.00 | 0.00 | 0.00 | 0.00 | 0.43 | 0.71 | 0.27 | 0.00 | 0.00 | 0.00 | 0.89 | 0.00 | 1.25 |
| PROL1 | ENSG00000171199 | 0.00 | 1.02 | 0.00 | 0.00 | 0.00 | 0.65 | 0.00 | 1.10 | 0.77 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 1.32 | 1.72 | 1.23 | 0.00 | 0.57 | 0.56 | 0.00 | 0.78 | 0.00 | 3.55 | 0.81 | 0.00 | 0.00 | 0.00 | 0.89 | 0.00 | 0.00 |
| MUC7 | ENSG00000171195 | 1.11 | 1.27 | 0.31 | 1.09 | 0.00 | 0.00 | 0.00 | 1.66 | 0.26 | 0.60 | 0.00 | 0.54 | 0.36 | 0.00 | 0.98 | 0.83 | 3.77 | 1.72 | 0.00 | 0.74 | 0.00 | 0.00 | 0.00 | 0.00 | 0.43 | 1.90 | 0.54 | 0.00 | 0.41 | 0.00 | 0.67 | 0.00 | 0.00 |
| AFM | ENSG00000079557 | 0.00 | 1.02 | 0.10 | 0.36 | 0.00 | 0.32 | 0.00 | 1.10 | 1.55 | 0.80 | 0.00 | 0.27 | 0.36 | 0.00 | 0.39 | 0.56 | 1.13 | 0.64 | 0.00 | 0.25 | 0.00 | 0.00 | 0.20 | 2.34 | 0.86 | 4.03 | 0.27 | 0.00 | 0.61 | 0.00 | 1.11 | 0.00 | 0.00 |
| IBSP | ENSG00000029559 | 0.00 | 0.76 | 0.31 | 0.36 | 2.86 | 0.65 | 0.00 | 1.66 | 0.00 | 0.60 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.56 | 0.75 | 1.50 | 0.00 | 0.00 | 0.57 | 0.00 | 0.00 | 2.34 | 0.00 | 1.66 | 0.27 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| THBS4 | ENSG00000113296 | 0.00 | 1.02 | 0.52 | 0.36 | 0.00 | 1.29 | 2.70 | 0.55 | 1.03 | 1.00 | 0.00 | 0.27 | 0.71 | 0.00 | 0.20 | 0.28 | 0.94 | 0.21 | 0.00 | 0.49 | 1.15 | 0.00 | 0.20 | 0.00 | 0.00 | 3.32 | 1.63 | 0.00 | 0.00 | 0.00 | 2.00 | 0.00 | 0.00 |
| IL3 | ENSG00000164399 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.32 | 0.00 | 0.55 | 0.52 | 0.20 | 0.00 | 0.27 | 0.00 | 0.00 | 0.00 | 0.00 | 0.75 | 0.21 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.78 | 0.00 | 0.71 | 0.27 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| CSF2 | ENSG00000164400 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.52 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.43 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.24 | 0.00 | 0.00 | 0.00 | 0.00 | 0.22 | 0.00 | 0.00 |
| FSTL4 | ENSG00000053108 | 1.11 | 1.02 | 0.52 | 0.73 | 0.00 | 0.65 | 0.00 | 2.21 | 0.77 | 0.60 | 1.54 | 0.81 | 0.71 | 0.00 | 0.00 | 0.83 | 0.94 | 0.64 | 0.00 | 0.74 | 0.57 | 0.00 | 0.20 | 0.00 | 0.43 | 2.61 | 1.08 | 0.00 | 0.20 | 0.00 | 1.77 | 0.00 | 0.00 |
| IL9 | ENSG00000145839 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.40 | 0.00 | 0.00 | 0.71 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.41 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| IL17B | ENSG00000127743 | 0.00 | 0.76 | 0.21 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 0.36 | 0.00 | 0.00 | 0.00 | 0.19 | 0.43 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.43 | 0.95 | 0.27 | 0.00 | 0.00 | 0.00 | 0.67 | 0.00 | 0.00 |
| IGHG1 | ENSG00000211896 | 0.00 | 1.27 | 0.10 | 0.73 | 0.00 | 2.26 | 21.62 | 0.55 | 0.52 | 1.20 | 0.00 | 0.00 | 0.36 | 0.00 | 0.00 | 1.11 | 0.94 | 1.07 | 0.00 | 0.25 | 0.00 | 0.00 | 0.61 | 0.00 | 0.43 | 2.84 | 1.08 | 0.00 | 0.00 | 0.00 | 1.11 | 0.00 | 0.00 |
| SFTA2 | ENSG00000196260 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.28 | 0.00 | 0.21 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.47 | 0.00 | 0.00 | 0.00 | 0.00 | 0.22 | 0.00 | 0.00 |
| COL12A1 | ENSG00000111799 | 0.00 | 4.83 | 1.96 | 2.55 | 0.00 | 5.16 | 2.70 | 5.52 | 2.32 | 1.39 | 0.00 | 0.54 | 1.07 | 0.74 | 1.18 | 4.17 | 8.85 | 10.30 | 0.00 | 0.49 | 0.57 | 0.56 | 1.43 | 5.47 | 2.16 | 9.48 | 8.67 | 0.69 | 0.20 | 0.83 | 3.33 | 0.00 | 1.25 |
|
Showing page 156 |
first page | previous page | next page | last page |
Copyright © 2020 University of Pennsylvania. All Rights Reserved.