Mutation
The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.
Summary of mutation frequency of the PDGs in each cancer type
| Showing page 133 |
first page | previous page | next page | last page |
| HGNC Symbol | Ensembl Gene ID | ACC_Mut% | BLCA_Mut% | BRCA_Mut% | CESC_Mut% | CHOL_Mut% | COAD_Mut% | DLBC_Mut% | ESCA_Mut% | GBM_Mut% | HNSC_Mut% | KICH_Mut% | KIRC_Mut% | KIRP_Mut% | LAML_Mut% | LGG_Mut% | LIHC_Mut% | LUAD_Mut% | LUSC_Mut% | MESO_Mut% | OV_Mut% | PAAD_Mut% | PCPG_Mut% | PRAD_Mut% | READ_Mut% | SARC_Mut% | SKCM_Mut% | STAD_Mut% | TGCT_Mut% | THCA_Mut% | THYM_Mut% | UCEC_Mut% | UCS_Mut% | UVM_Mut% |
| TPSAB1 | ENSG00000172236 | 0.00 | 0.51 | 0.10 | 0.73 | 0.00 | 0.00 | 0.00 | 1.10 | 0.26 | 0.20 | 0.00 | 0.27 | 0.00 | 0.00 | 0.00 | 0.00 | 0.19 | 0.43 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.78 | 0.00 | 0.24 | 0.54 | 0.00 | 0.00 | 0.00 | 0.22 | 0.00 | 0.00 |
| PRSS22 | ENSG00000005001 | 0.00 | 0.00 | 0.10 | 0.36 | 0.00 | 0.00 | 0.00 | 1.10 | 0.00 | 0.20 | 0.00 | 0.00 | 0.36 | 0.00 | 0.00 | 0.28 | 0.56 | 0.64 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 0.71 | 0.81 | 0.00 | 0.00 | 0.00 | 0.67 | 0.00 | 0.00 |
| MMP25 | ENSG00000008516 | 0.00 | 0.76 | 0.10 | 0.00 | 0.00 | 0.32 | 0.00 | 0.00 | 0.00 | 0.60 | 0.00 | 0.27 | 0.00 | 0.74 | 0.00 | 0.00 | 1.32 | 1.07 | 1.23 | 0.25 | 0.00 | 0.00 | 0.20 | 0.00 | 0.43 | 1.90 | 0.54 | 0.00 | 0.00 | 0.83 | 0.44 | 3.64 | 0.00 |
| DNASE1 | ENSG00000213918 | 1.11 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.55 | 0.00 | 0.20 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.19 | 0.21 | 0.00 | 0.00 | 0.57 | 0.56 | 0.00 | 0.00 | 0.43 | 0.24 | 0.00 | 0.00 | 0.00 | 0.83 | 0.22 | 0.00 | 0.00 |
| PRSS36 | ENSG00000178226 | 0.00 | 1.02 | 0.10 | 0.00 | 0.00 | 0.00 | 2.70 | 1.10 | 1.03 | 0.40 | 0.00 | 0.27 | 0.00 | 0.00 | 0.00 | 0.56 | 1.32 | 1.07 | 0.00 | 0.25 | 0.00 | 0.00 | 0.00 | 0.00 | 0.43 | 2.13 | 0.27 | 0.00 | 0.00 | 0.00 | 2.00 | 0.00 | 0.00 |
| NTN1 | ENSG00000065320 | 1.11 | 0.76 | 0.00 | 1.46 | 0.00 | 0.32 | 0.00 | 0.00 | 0.52 | 0.40 | 0.00 | 0.00 | 0.36 | 0.00 | 0.20 | 0.56 | 0.19 | 0.64 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.56 | 0.43 | 0.24 | 0.00 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| CCL7 | ENSG00000108688 | 0.00 | 0.51 | 0.00 | 0.00 | 0.00 | 0.32 | 0.00 | 0.55 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.56 | 0.86 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 0.71 | 0.00 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| GH2 | ENSG00000136487 | 0.00 | 0.25 | 0.31 | 0.36 | 0.00 | 0.32 | 0.00 | 0.00 | 0.00 | 0.60 | 0.00 | 0.27 | 0.00 | 0.00 | 0.00 | 0.28 | 1.32 | 0.86 | 0.00 | 0.25 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 1.42 | 0.54 | 0.00 | 0.00 | 0.00 | 0.22 | 0.00 | 0.00 |
| FASN | ENSG00000169710 | 1.11 | 2.04 | 1.34 | 1.09 | 0.00 | 1.94 | 2.70 | 1.66 | 0.26 | 1.59 | 0.00 | 1.08 | 1.42 | 0.00 | 0.20 | 5.28 | 2.07 | 1.72 | 0.00 | 0.49 | 0.57 | 0.00 | 0.20 | 3.13 | 2.59 | 3.55 | 0.81 | 0.00 | 0.20 | 0.00 | 5.10 | 0.00 | 0.00 |
| CSNK1D | ENSG00000141551 | 0.00 | 0.76 | 0.10 | 0.36 | 0.00 | 0.32 | 0.00 | 0.55 | 0.26 | 0.40 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.13 | 0.43 | 0.00 | 0.49 | 0.00 | 0.00 | 0.00 | 0.78 | 0.00 | 0.00 | 0.27 | 0.00 | 0.20 | 0.00 | 0.67 | 0.00 | 0.00 |
| PRKACA | ENSG00000072062 | 0.00 | 0.51 | 0.41 | 0.36 | 0.00 | 0.00 | 2.70 | 0.55 | 0.52 | 0.60 | 0.00 | 0.27 | 0.36 | 0.00 | 0.00 | 0.56 | 0.38 | 0.21 | 0.00 | 0.49 | 0.00 | 0.00 | 0.41 | 0.00 | 0.86 | 0.71 | 0.54 | 0.00 | 0.00 | 0.00 | 2.00 | 0.00 | 0.00 |
| MRC1 | ENSG00000260314 | |||||||||||||||||||||||||||||||||
| PRKCE | ENSG00000171132 | 0.00 | 1.02 | 0.72 | 0.73 | 0.00 | 0.97 | 0.00 | 0.55 | 0.00 | 0.60 | 0.00 | 0.54 | 0.71 | 0.00 | 0.00 | 0.28 | 1.32 | 1.93 | 0.00 | 0.49 | 0.00 | 0.00 | 0.00 | 0.00 | 0.43 | 1.18 | 1.36 | 0.00 | 0.00 | 0.00 | 0.89 | 1.82 | 0.00 |
| ZAP70 | ENSG00000115085 | 0.00 | 0.25 | 0.21 | 0.36 | 0.00 | 2.26 | 2.70 | 0.55 | 0.77 | 0.60 | 0.00 | 0.27 | 0.36 | 0.74 | 0.20 | 1.11 | 1.51 | 2.15 | 0.00 | 0.25 | 0.57 | 0.00 | 0.41 | 0.00 | 0.86 | 1.42 | 0.81 | 0.00 | 0.00 | 0.00 | 0.89 | 0.00 | 0.00 |
| CST9L | ENSG00000101435 | 0.00 | 0.51 | 0.10 | 0.36 | 0.00 | 0.00 | 0.00 | 0.00 | 0.26 | 0.20 | 0.00 | 0.27 | 0.36 | 0.00 | 0.00 | 0.56 | 0.38 | 0.64 | 0.00 | 0.25 | 0.00 | 0.00 | 0.00 | 0.00 | 0.43 | 0.71 | 0.00 | 0.00 | 0.00 | 0.00 | 0.22 | 0.00 | 0.00 |
| WFDC2 | ENSG00000101443 | 0.00 | 0.00 | 0.21 | 0.36 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 0.36 | 0.00 | 0.00 | 0.00 | 0.19 | 0.21 | 0.00 | 0.25 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.71 | 0.00 | 0.00 | 0.00 | 0.00 | 0.22 | 0.00 | 0.00 |
| CTSA | ENSG00000064601 | 0.00 | 0.76 | 0.10 | 0.00 | 0.00 | 0.32 | 0.00 | 0.00 | 0.26 | 0.20 | 0.00 | 1.08 | 0.36 | 0.00 | 0.20 | 0.00 | 0.56 | 0.86 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.42 | 0.27 | 0.00 | 0.00 | 0.00 | 1.11 | 0.00 | 0.00 |
| SPPL2B | ENSG00000005206 | |||||||||||||||||||||||||||||||||
| WNT7B | ENSG00000188064 | 0.00 | 0.00 | 0.00 | 1.09 | 0.00 | 0.32 | 2.70 | 1.10 | 0.26 | 0.20 | 0.00 | 0.27 | 0.00 | 0.00 | 0.00 | 0.28 | 0.94 | 0.64 | 1.23 | 0.49 | 1.15 | 0.00 | 0.00 | 0.00 | 0.43 | 0.47 | 0.27 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| SPINK8 | ENSG00000229453 | 0.00 | 0.25 | 0.10 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.22 | 0.00 | 0.00 |
|
Showing page 133 |
first page | previous page | next page | last page |
Copyright © 2020 University of Pennsylvania. All Rights Reserved.