Mutation
The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.
Summary of mutation frequency of the PDGs in each cancer type
| Showing page 120 |
first page | previous page | next page | last page |
| HGNC Symbol | Ensembl Gene ID | ACC_Mut% | BLCA_Mut% | BRCA_Mut% | CESC_Mut% | CHOL_Mut% | COAD_Mut% | DLBC_Mut% | ESCA_Mut% | GBM_Mut% | HNSC_Mut% | KICH_Mut% | KIRC_Mut% | KIRP_Mut% | LAML_Mut% | LGG_Mut% | LIHC_Mut% | LUAD_Mut% | LUSC_Mut% | MESO_Mut% | OV_Mut% | PAAD_Mut% | PCPG_Mut% | PRAD_Mut% | READ_Mut% | SARC_Mut% | SKCM_Mut% | STAD_Mut% | TGCT_Mut% | THCA_Mut% | THYM_Mut% | UCEC_Mut% | UCS_Mut% | UVM_Mut% |
| WNT7A | ENSG00000154764 | 0.00 | 1.02 | 0.52 | 0.00 | 0.00 | 1.29 | 0.00 | 0.00 | 0.26 | 0.20 | 0.00 | 0.00 | 0.36 | 0.00 | 0.39 | 0.28 | 2.26 | 1.50 | 0.00 | 0.49 | 0.57 | 0.00 | 0.00 | 0.00 | 0.00 | 2.37 | 0.81 | 0.00 | 0.00 | 0.00 | 0.22 | 0.00 | 0.00 |
| LVRN | ENSG00000172901 | 2.22 | 1.53 | 0.10 | 1.09 | 0.00 | 1.94 | 0.00 | 1.10 | 0.00 | 1.20 | 0.00 | 1.36 | 0.71 | 0.00 | 0.20 | 1.39 | 3.20 | 3.00 | 1.23 | 0.98 | 0.00 | 0.00 | 0.20 | 1.56 | 0.00 | 5.21 | 1.36 | 0.00 | 0.00 | 0.00 | 2.22 | 0.00 | 0.00 |
| CHST7 | ENSG00000147119 | 0.00 | 0.51 | 0.21 | 0.73 | 0.00 | 0.32 | 0.00 | 0.55 | 0.00 | 0.00 | 0.00 | 0.27 | 0.36 | 0.00 | 0.00 | 0.28 | 0.38 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.24 | 0.54 | 0.00 | 0.00 | 0.00 | 1.11 | 0.00 | 0.00 |
| SERPINC1 | ENSG00000117601 | 0.00 | 2.04 | 0.52 | 0.36 | 0.00 | 0.32 | 2.70 | 0.00 | 0.26 | 0.80 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.83 | 0.56 | 1.29 | 0.00 | 0.49 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.66 | 0.54 | 0.00 | 0.00 | 0.00 | 0.67 | 0.00 | 0.00 |
| NOD2 | ENSG00000167207 | 0.00 | 1.02 | 0.31 | 1.46 | 0.00 | 1.29 | 0.00 | 1.10 | 0.52 | 0.80 | 0.00 | 0.81 | 0.00 | 0.00 | 0.20 | 1.39 | 3.01 | 3.65 | 0.00 | 1.23 | 0.57 | 0.00 | 0.20 | 0.78 | 0.00 | 3.32 | 1.08 | 0.00 | 0.00 | 0.00 | 1.33 | 1.82 | 1.25 |
| CHST6 | ENSG00000183196 | 0.00 | 0.25 | 0.00 | 0.00 | 0.00 | 0.97 | 2.70 | 1.10 | 0.52 | 1.39 | 0.00 | 0.00 | 0.36 | 1.47 | 0.00 | 0.00 | 0.94 | 1.50 | 1.23 | 0.25 | 0.57 | 0.00 | 0.00 | 0.00 | 0.00 | 0.47 | 0.54 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| AAK1 | ENSG00000115977 | 0.00 | 0.25 | 0.41 | 0.73 | 0.00 | 0.97 | 0.00 | 1.66 | 0.00 | 1.00 | 0.00 | 0.27 | 0.36 | 0.00 | 0.00 | 0.56 | 0.94 | 1.29 | 0.00 | 0.00 | 0.00 | 0.56 | 0.20 | 0.00 | 0.86 | 0.95 | 0.27 | 0.69 | 0.00 | 0.00 | 0.67 | 0.00 | 0.00 |
| LYPD6 | ENSG00000187123 | 0.00 | 0.51 | 0.10 | 0.00 | 0.00 | 0.32 | 0.00 | 0.55 | 0.00 | 0.20 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.28 | 0.19 | 0.21 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.47 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| EPO | ENSG00000130427 | 0.00 | 0.25 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.26 | 0.20 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.75 | 0.64 | 0.00 | 0.49 | 0.00 | 0.00 | 0.00 | 0.00 | 0.43 | 1.42 | 0.27 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| PIK3CG | ENSG00000105851 | 0.00 | 2.29 | 0.31 | 1.09 | 0.00 | 2.58 | 2.70 | 0.55 | 3.09 | 2.99 | 0.00 | 0.81 | 0.36 | 0.00 | 0.20 | 1.11 | 5.08 | 6.65 | 0.00 | 1.47 | 1.15 | 0.00 | 1.22 | 2.34 | 0.43 | 4.98 | 2.98 | 0.00 | 0.20 | 0.00 | 2.88 | 1.82 | 0.00 |
| FGR | ENSG00000000938 | 0.00 | 0.76 | 0.10 | 0.73 | 0.00 | 0.65 | 0.00 | 0.55 | 0.00 | 0.40 | 0.00 | 0.27 | 0.71 | 0.00 | 0.00 | 0.83 | 0.75 | 0.43 | 0.00 | 0.74 | 0.00 | 0.00 | 0.20 | 0.00 | 0.43 | 1.18 | 0.00 | 0.00 | 0.00 | 0.00 | 1.55 | 0.00 | 0.00 |
| TNR | ENSG00000116147 | 2.22 | 3.05 | 1.24 | 0.73 | 0.00 | 3.87 | 0.00 | 3.31 | 0.26 | 2.99 | 0.00 | 1.63 | 0.36 | 0.00 | 0.20 | 2.50 | 13.56 | 15.02 | 1.23 | 1.23 | 2.30 | 0.00 | 0.41 | 4.69 | 1.72 | 14.22 | 2.17 | 0.00 | 0.41 | 0.83 | 3.10 | 0.00 | 0.00 |
| CFLAR | ENSG00000003402 | 0.00 | 0.76 | 0.10 | 0.00 | 0.00 | 0.32 | 0.00 | 0.00 | 0.26 | 0.20 | 0.00 | 0.54 | 0.71 | 0.00 | 0.00 | 0.28 | 0.00 | 1.29 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 0.47 | 0.00 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| OSM | ENSG00000099985 | 0.00 | 0.51 | 0.00 | 0.36 | 0.00 | 0.65 | 0.00 | 0.00 | 0.26 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.75 | 0.21 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.42 | 0.00 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 1.25 |
| C4A | ENSG00000244731 | 0.00 | 0.25 | 0.21 | 0.00 | 0.00 | 0.00 | 2.70 | 0.00 | 0.00 | 0.40 | 0.00 | 0.00 | 0.71 | 0.00 | 0.20 | 0.28 | 0.19 | 0.43 | 0.00 | 0.25 | 0.57 | 0.00 | 0.00 | 0.00 | 0.00 | 1.90 | 0.27 | 0.00 | 0.20 | 0.00 | 0.22 | 0.00 | 0.00 |
| TNN | ENSG00000120332 | 1.11 | 3.56 | 1.14 | 1.09 | 0.00 | 3.87 | 5.41 | 3.87 | 1.03 | 3.78 | 0.00 | 0.54 | 0.36 | 0.74 | 0.59 | 2.22 | 10.92 | 12.23 | 0.00 | 1.72 | 0.57 | 0.00 | 0.61 | 1.56 | 0.43 | 9.95 | 3.79 | 0.00 | 0.00 | 0.83 | 2.88 | 0.00 | 0.00 |
| WNT3A | ENSG00000154342 | 0.00 | 0.76 | 0.10 | 0.00 | 0.00 | 0.97 | 0.00 | 0.55 | 0.00 | 0.00 | 0.00 | 0.27 | 0.00 | 0.00 | 0.00 | 0.28 | 1.51 | 2.15 | 0.00 | 0.00 | 1.72 | 0.00 | 0.20 | 0.00 | 0.00 | 1.66 | 1.08 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| IFNG | ENSG00000111537 | 0.00 | 0.51 | 0.21 | 0.36 | 0.00 | 0.65 | 0.00 | 0.00 | 0.52 | 0.20 | 0.00 | 0.00 | 0.71 | 0.00 | 0.00 | 0.56 | 1.13 | 0.43 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.43 | 1.18 | 0.27 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| ILK | ENSG00000166333 | 0.00 | 0.51 | 0.31 | 0.73 | 0.00 | 0.00 | 2.70 | 0.55 | 0.00 | 0.60 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.21 | 0.00 | 0.49 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 0.47 | 0.81 | 0.00 | 0.00 | 0.00 | 2.00 | 0.00 | 0.00 |
| TUBB6 | ENSG00000176014 | 0.00 | 1.53 | 0.21 | 0.00 | 0.00 | 0.32 | 0.00 | 1.10 | 0.00 | 0.60 | 0.00 | 0.00 | 0.00 | 0.74 | 0.00 | 0.28 | 0.56 | 0.64 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.43 | 1.42 | 0.54 | 0.00 | 0.00 | 0.00 | 1.11 | 0.00 | 0.00 |
|
Showing page 120 |
first page | previous page | next page | last page |
Copyright © 2020 University of Pennsylvania. All Rights Reserved.