Mutation
The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.
Summary of mutation frequency of the PDGs in each cancer type
| Showing page 118 |
first page | previous page | next page | last page |
| HGNC Symbol | Ensembl Gene ID | ACC_Mut% | BLCA_Mut% | BRCA_Mut% | CESC_Mut% | CHOL_Mut% | COAD_Mut% | DLBC_Mut% | ESCA_Mut% | GBM_Mut% | HNSC_Mut% | KICH_Mut% | KIRC_Mut% | KIRP_Mut% | LAML_Mut% | LGG_Mut% | LIHC_Mut% | LUAD_Mut% | LUSC_Mut% | MESO_Mut% | OV_Mut% | PAAD_Mut% | PCPG_Mut% | PRAD_Mut% | READ_Mut% | SARC_Mut% | SKCM_Mut% | STAD_Mut% | TGCT_Mut% | THCA_Mut% | THYM_Mut% | UCEC_Mut% | UCS_Mut% | UVM_Mut% |
| SLC17A8 | ENSG00000179520 | 0.00 | 0.76 | 0.21 | 0.36 | 0.00 | 0.65 | 0.00 | 0.00 | 0.52 | 1.20 | 0.00 | 0.54 | 1.07 | 0.00 | 0.00 | 0.56 | 2.82 | 5.58 | 0.00 | 0.74 | 0.00 | 0.00 | 0.20 | 0.00 | 0.43 | 4.50 | 0.27 | 0.00 | 0.00 | 0.00 | 1.11 | 0.00 | 0.00 |
| ABCB9 | ENSG00000150967 | 0.00 | 0.25 | 0.00 | 0.73 | 0.00 | 0.00 | 0.00 | 0.55 | 0.26 | 0.20 | 0.00 | 0.00 | 0.36 | 0.74 | 0.20 | 0.00 | 1.13 | 0.86 | 0.00 | 0.49 | 0.00 | 0.00 | 0.20 | 0.78 | 0.00 | 1.90 | 0.27 | 0.00 | 0.00 | 0.83 | 0.89 | 0.00 | 0.00 |
| ATP12A | ENSG00000075673 | 0.00 | 3.56 | 0.41 | 0.00 | 0.00 | 2.26 | 0.00 | 0.55 | 1.03 | 1.59 | 1.54 | 0.81 | 0.71 | 0.00 | 0.78 | 1.94 | 2.07 | 2.15 | 0.00 | 1.23 | 2.30 | 0.56 | 0.61 | 0.78 | 0.43 | 3.79 | 1.08 | 0.00 | 0.20 | 0.00 | 1.11 | 0.00 | 0.00 |
| LECT1 | ENSG00000136110 | 0.00 | 0.51 | 0.10 | 0.00 | 0.00 | 0.32 | 0.00 | 0.55 | 0.77 | 0.20 | 0.00 | 0.27 | 0.36 | 0.00 | 0.00 | 0.00 | 0.94 | 0.00 | 0.00 | 0.25 | 0.00 | 0.00 | 0.41 | 0.78 | 0.00 | 1.42 | 0.54 | 0.00 | 0.00 | 0.00 | 0.22 | 1.82 | 0.00 |
| TMX1 | ENSG00000139921 | 0.00 | 0.25 | 0.10 | 0.36 | 0.00 | 0.32 | 0.00 | 0.00 | 0.26 | 0.20 | 0.00 | 0.00 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 0.43 | 0.00 | 0.25 | 0.57 | 0.00 | 0.00 | 0.00 | 0.00 | 0.47 | 0.27 | 0.00 | 0.00 | 0.00 | 1.11 | 0.00 | 0.00 |
| HSD17B2 | ENSG00000086696 | 0.00 | 0.76 | 0.10 | 0.00 | 0.00 | 0.65 | 0.00 | 0.00 | 0.00 | 0.40 | 0.00 | 0.27 | 0.00 | 0.00 | 0.00 | 0.00 | 0.38 | 0.21 | 0.00 | 0.74 | 0.57 | 0.00 | 0.20 | 0.78 | 0.43 | 2.37 | 0.00 | 0.00 | 0.00 | 0.00 | 0.22 | 0.00 | 0.00 |
| CHST9 | ENSG00000154080 | 1.11 | 0.76 | 0.52 | 0.36 | 0.00 | 1.61 | 2.70 | 2.21 | 0.00 | 0.60 | 0.00 | 0.54 | 0.36 | 0.00 | 0.00 | 0.28 | 0.56 | 0.86 | 0.00 | 0.49 | 0.00 | 0.00 | 0.00 | 0.78 | 0.00 | 1.66 | 0.81 | 0.00 | 0.00 | 0.00 | 0.22 | 0.00 | 0.00 |
| GALNT1 | ENSG00000141429 | 0.00 | 1.27 | 0.41 | 0.36 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.40 | 0.00 | 0.27 | 0.00 | 0.00 | 0.59 | 0.56 | 0.75 | 0.64 | 0.00 | 0.49 | 0.57 | 0.00 | 0.00 | 0.00 | 0.00 | 1.18 | 0.00 | 0.69 | 0.00 | 0.00 | 0.67 | 0.00 | 0.00 |
| UGT1A9 | ENSG00000241119 | 0.00 | 0.76 | 0.31 | 0.00 | 0.00 | 0.00 | 0.00 | 0.55 | 0.77 | 0.00 | 1.54 | 0.00 | 1.07 | 0.00 | 0.00 | 0.28 | 0.94 | 0.64 | 0.00 | 0.98 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 3.55 | 0.00 | 0.00 | 0.00 | 0.00 | 1.11 | 0.00 | 0.00 |
| SLC12A8 | ENSG00000221955 | 1.11 | 0.25 | 0.21 | 0.73 | 0.00 | 0.00 | 0.00 | 0.55 | 0.00 | 1.00 | 0.00 | 0.54 | 0.00 | 0.00 | 0.00 | 0.83 | 0.75 | 1.29 | 0.00 | 0.74 | 0.00 | 0.56 | 0.20 | 0.00 | 0.43 | 3.08 | 0.27 | 0.69 | 0.00 | 0.00 | 1.11 | 0.00 | 0.00 |
| SLC7A14 | ENSG00000013293 | 1.11 | 1.27 | 0.31 | 1.46 | 0.00 | 0.32 | 0.00 | 1.66 | 0.52 | 1.79 | 0.00 | 0.27 | 0.71 | 0.74 | 0.20 | 0.28 | 1.69 | 1.93 | 0.00 | 0.49 | 0.00 | 0.00 | 0.20 | 0.78 | 1.29 | 2.37 | 1.08 | 0.00 | 0.00 | 0.83 | 1.11 | 0.00 | 0.00 |
| NAALADL2 | ENSG00000177694 | 2.22 | 1.78 | 1.03 | 1.82 | 0.00 | 1.29 | 0.00 | 1.66 | 0.77 | 2.39 | 0.00 | 0.27 | 0.00 | 0.00 | 0.20 | 0.28 | 1.69 | 2.36 | 1.23 | 0.49 | 0.00 | 0.00 | 0.20 | 3.13 | 0.00 | 2.61 | 1.63 | 0.00 | 0.00 | 0.00 | 1.33 | 0.00 | 0.00 |
| TMPRSS11A | ENSG00000187054 | 0.00 | 0.00 | 0.10 | 0.36 | 0.00 | 2.26 | 0.00 | 0.00 | 0.77 | 0.00 | 0.00 | 0.27 | 0.36 | 0.00 | 0.00 | 0.00 | 2.26 | 1.07 | 0.00 | 0.25 | 0.00 | 0.00 | 0.00 | 2.34 | 0.43 | 3.08 | 0.54 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| SLC7A11 | ENSG00000151012 | 0.00 | 0.00 | 0.21 | 0.73 | 0.00 | 1.29 | 0.00 | 1.10 | 0.26 | 0.80 | 0.00 | 0.54 | 0.00 | 0.00 | 0.00 | 0.28 | 0.19 | 0.64 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.78 | 0.00 | 2.13 | 0.00 | 0.00 | 0.20 | 0.00 | 0.67 | 0.00 | 0.00 |
| SV2C | ENSG00000122012 | 1.11 | 1.27 | 0.00 | 0.73 | 0.00 | 1.61 | 0.00 | 0.55 | 1.29 | 0.80 | 0.00 | 0.81 | 0.71 | 0.00 | 0.20 | 0.28 | 2.64 | 3.00 | 1.23 | 0.74 | 0.00 | 0.00 | 0.00 | 0.00 | 0.86 | 4.03 | 0.81 | 0.00 | 0.20 | 0.00 | 2.00 | 0.00 | 0.00 |
| ABCA13 | ENSG00000179869 | 2.22 | 7.89 | 2.79 | 4.38 | 2.86 | 11.29 | 5.41 | 6.08 | 1.03 | 5.98 | 0.00 | 3.25 | 2.49 | 0.74 | 1.76 | 8.89 | 12.81 | 12.23 | 0.00 | 2.94 | 2.30 | 3.37 | 2.24 | 7.81 | 1.72 | 14.22 | 7.32 | 1.39 | 0.20 | 0.00 | 7.98 | 1.82 | 1.25 |
| SVOPL | ENSG00000157703 | 0.00 | 1.02 | 0.00 | 0.36 | 0.00 | 0.65 | 0.00 | 0.55 | 1.03 | 0.20 | 0.00 | 0.27 | 0.71 | 0.00 | 0.00 | 0.00 | 0.75 | 0.43 | 1.23 | 0.25 | 0.00 | 0.56 | 0.00 | 0.00 | 0.43 | 2.84 | 0.54 | 0.00 | 0.20 | 0.00 | 0.44 | 0.00 | 0.00 |
| POMK | ENSG00000185900 | 0.00 | 0.25 | 0.21 | 0.00 | 0.00 | 0.32 | 0.00 | 0.00 | 0.52 | 0.20 | 0.00 | 0.27 | 0.36 | 0.00 | 0.00 | 0.28 | 0.56 | 0.64 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.47 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| ENPP2 | ENSG00000136960 | 2.22 | 1.27 | 1.03 | 1.46 | 0.00 | 0.65 | 0.00 | 0.55 | 1.29 | 1.79 | 0.00 | 0.81 | 0.00 | 0.00 | 0.20 | 0.28 | 2.64 | 3.65 | 0.00 | 1.47 | 0.00 | 0.00 | 0.41 | 0.00 | 0.00 | 1.90 | 1.08 | 0.00 | 0.41 | 0.00 | 2.22 | 1.82 | 0.00 |
| SLC31A2 | ENSG00000136867 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.19 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.86 | 0.24 | 0.00 | 0.00 | 0.20 | 0.00 | 0.22 | 0.00 | 0.00 |
|
Showing page 118 |
first page | previous page | next page | last page |
Copyright © 2020 University of Pennsylvania. All Rights Reserved.