Mutation
The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.
Summary of mutation frequency of the PDGs in each cancer type
| Showing page 105 |
first page | previous page | next page | last page |
| HGNC Symbol | Ensembl Gene ID | ACC_Mut% | BLCA_Mut% | BRCA_Mut% | CESC_Mut% | CHOL_Mut% | COAD_Mut% | DLBC_Mut% | ESCA_Mut% | GBM_Mut% | HNSC_Mut% | KICH_Mut% | KIRC_Mut% | KIRP_Mut% | LAML_Mut% | LGG_Mut% | LIHC_Mut% | LUAD_Mut% | LUSC_Mut% | MESO_Mut% | OV_Mut% | PAAD_Mut% | PCPG_Mut% | PRAD_Mut% | READ_Mut% | SARC_Mut% | SKCM_Mut% | STAD_Mut% | TGCT_Mut% | THCA_Mut% | THYM_Mut% | UCEC_Mut% | UCS_Mut% | UVM_Mut% |
| EFEMP1 | ENSG00000115380 | 0.00 | 1.78 | 0.72 | 0.36 | 0.00 | 2.90 | 0.00 | 1.10 | 0.00 | 0.20 | 0.00 | 0.00 | 0.00 | 0.00 | 0.59 | 1.94 | 0.00 | 1.07 | 0.00 | 0.74 | 0.00 | 0.00 | 0.20 | 0.78 | 0.43 | 1.90 | 0.54 | 0.00 | 0.00 | 0.00 | 1.11 | 0.00 | 0.00 |
| FSTL1 | ENSG00000163430 | 0.00 | 0.51 | 0.00 | 0.73 | 0.00 | 0.65 | 0.00 | 1.66 | 0.52 | 0.40 | 0.00 | 0.27 | 0.00 | 0.00 | 0.00 | 0.28 | 0.56 | 1.50 | 0.00 | 0.25 | 0.00 | 0.00 | 0.00 | 0.78 | 0.00 | 0.24 | 0.54 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| COL6A5 | ENSG00000172752 | 2.22 | 3.05 | 1.45 | 3.28 | 0.00 | 3.23 | 5.41 | 7.18 | 1.55 | 1.00 | 1.54 | 1.36 | 1.07 | 0.00 | 0.20 | 2.78 | 2.07 | 3.86 | 2.47 | 0.98 | 0.57 | 0.00 | 0.20 | 4.69 | 0.86 | 4.50 | 0.81 | 0.69 | 0.00 | 0.83 | 3.99 | 0.00 | 0.00 |
| AHSG | ENSG00000145192 | 0.00 | 1.27 | 0.10 | 0.00 | 0.00 | 0.32 | 0.00 | 0.00 | 0.00 | 0.60 | 0.00 | 0.27 | 0.36 | 0.00 | 0.00 | 0.28 | 1.51 | 2.15 | 0.00 | 0.49 | 0.00 | 0.00 | 0.20 | 0.00 | 0.00 | 1.66 | 1.08 | 0.00 | 0.00 | 0.00 | 1.11 | 0.00 | 0.00 |
| SCUBE3 | ENSG00000146197 | 1.11 | 1.02 | 0.21 | 1.09 | 0.00 | 0.97 | 0.00 | 1.10 | 0.26 | 0.80 | 0.00 | 0.00 | 0.36 | 0.00 | 0.20 | 1.11 | 0.38 | 1.07 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.78 | 0.43 | 2.84 | 1.08 | 0.00 | 0.00 | 0.00 | 2.00 | 0.00 | 0.00 |
| LAMB1 | ENSG00000091136 | 0.00 | 2.54 | 0.93 | 1.46 | 0.00 | 1.61 | 5.41 | 2.76 | 0.26 | 1.59 | 0.00 | 1.63 | 1.42 | 1.47 | 0.39 | 1.67 | 5.65 | 3.00 | 0.00 | 2.70 | 0.00 | 0.00 | 1.22 | 3.13 | 0.86 | 3.32 | 1.36 | 0.00 | 0.20 | 0.00 | 3.77 | 0.00 | 0.00 |
| TNFRSF11B | ENSG00000164761 | 0.00 | 0.25 | 0.41 | 0.73 | 0.00 | 1.61 | 0.00 | 0.00 | 0.52 | 0.20 | 0.00 | 0.27 | 0.00 | 0.00 | 0.39 | 0.56 | 0.56 | 0.86 | 0.00 | 0.74 | 0.00 | 0.00 | 0.41 | 0.00 | 0.00 | 2.37 | 0.54 | 0.00 | 0.00 | 0.83 | 1.11 | 0.00 | 0.00 |
| ORM1 | ENSG00000229314 | 0.00 | 0.00 | 0.10 | 0.36 | 0.00 | 0.00 | 2.70 | 0.00 | 0.26 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.56 | 0.38 | 0.43 | 0.00 | 0.25 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.95 | 0.81 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| DRD2 | ENSG00000149295 | 0.00 | 0.51 | 0.21 | 0.36 | 0.00 | 0.00 | 0.00 | 1.10 | 0.26 | 0.60 | 0.00 | 0.54 | 0.00 | 0.00 | 0.00 | 1.11 | 2.45 | 1.29 | 0.00 | 0.74 | 0.57 | 0.00 | 0.20 | 0.00 | 0.43 | 3.55 | 0.27 | 0.00 | 0.00 | 0.00 | 1.33 | 0.00 | 0.00 |
| MC4R | ENSG00000166603 | 0.00 | 0.76 | 0.21 | 0.00 | 0.00 | 0.32 | 0.00 | 1.66 | 0.77 | 0.80 | 0.00 | 0.27 | 0.00 | 0.00 | 0.20 | 0.56 | 0.56 | 1.29 | 0.00 | 0.25 | 0.00 | 0.00 | 0.20 | 0.78 | 0.00 | 0.24 | 1.08 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| GPR88 | ENSG00000181656 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.32 | 0.00 | 0.55 | 0.00 | 0.00 | 0.00 | 0.27 | 0.00 | 0.74 | 0.00 | 0.00 | 0.19 | 0.00 | 1.23 | 0.49 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| OPN4 | ENSG00000122375 | 1.11 | 0.25 | 0.41 | 0.00 | 0.00 | 0.97 | 0.00 | 1.10 | 0.26 | 0.60 | 1.54 | 0.54 | 0.36 | 0.00 | 0.39 | 1.39 | 1.88 | 0.21 | 0.00 | 0.49 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.66 | 0.27 | 0.00 | 0.41 | 0.00 | 1.55 | 0.00 | 0.00 |
| OR5AN1 | ENSG00000176495 | 0.00 | 0.25 | 0.31 | 0.36 | 0.00 | 1.61 | 0.00 | 0.55 | 0.52 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.39 | 0.28 | 1.88 | 1.07 | 0.00 | 0.25 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.95 | 0.27 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| PTGDR | ENSG00000168229 | 0.00 | 0.76 | 0.21 | 1.09 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.60 | 0.00 | 0.27 | 0.36 | 0.00 | 0.00 | 0.56 | 1.13 | 1.50 | 0.00 | 0.25 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 2.37 | 0.54 | 0.00 | 0.00 | 0.00 | 1.11 | 0.00 | 0.00 |
| ADGRG5 | ENSG00000159618 | 0.00 | 1.02 | 0.21 | 0.36 | 0.00 | 0.32 | 2.70 | 0.00 | 0.52 | 0.40 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.83 | 0.56 | 1.07 | 1.23 | 0.49 | 0.57 | 0.00 | 0.00 | 0.78 | 0.00 | 1.66 | 0.81 | 0.69 | 0.20 | 0.00 | 0.44 | 0.00 | 0.00 |
| ADGRG3 | ENSG00000182885 | 0.00 | 1.53 | 0.41 | 0.36 | 0.00 | 0.65 | 0.00 | 0.55 | 0.00 | 0.20 | 0.00 | 0.00 | 0.71 | 0.74 | 0.20 | 0.28 | 1.32 | 2.15 | 0.00 | 0.25 | 0.00 | 0.00 | 0.20 | 0.00 | 0.43 | 2.61 | 0.54 | 0.00 | 0.00 | 0.00 | 1.11 | 1.82 | 0.00 |
| OR1D2 | ENSG00000184166 | 0.00 | 0.51 | 0.00 | 0.00 | 0.00 | 0.32 | 2.70 | 0.00 | 0.26 | 0.80 | 0.00 | 0.54 | 0.00 | 0.00 | 0.20 | 0.00 | 0.56 | 1.50 | 1.23 | 0.25 | 0.00 | 0.00 | 0.20 | 0.00 | 0.43 | 2.37 | 0.27 | 0.00 | 0.00 | 0.00 | 0.44 | 0.00 | 0.00 |
| FPR1 | ENSG00000171051 | 1.11 | 0.76 | 0.10 | 0.00 | 2.86 | 0.97 | 0.00 | 1.10 | 0.52 | 0.60 | 0.00 | 0.27 | 0.00 | 0.00 | 0.20 | 0.28 | 1.69 | 1.29 | 0.00 | 0.00 | 0.57 | 0.00 | 0.61 | 2.34 | 0.43 | 4.50 | 0.27 | 0.00 | 0.20 | 0.00 | 0.44 | 0.00 | 0.00 |
| GPR75 | ENSG00000119737 | 0.00 | 1.78 | 0.10 | 0.00 | 0.00 | 0.00 | 0.00 | 0.55 | 0.52 | 0.80 | 0.00 | 0.54 | 0.00 | 0.00 | 0.00 | 0.00 | 0.56 | 0.43 | 0.00 | 0.49 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.18 | 0.27 | 0.00 | 0.00 | 0.00 | 1.11 | 0.00 | 0.00 |
| OPRM1 | ENSG00000112038 | 0.00 | 0.00 | 0.41 | 0.73 | 0.00 | 1.94 | 2.70 | 0.55 | 1.03 | 1.00 | 0.00 | 1.08 | 0.36 | 0.74 | 0.20 | 1.67 | 1.32 | 1.50 | 0.00 | 0.25 | 0.00 | 0.00 | 0.20 | 0.78 | 0.43 | 0.95 | 0.81 | 0.00 | 0.00 | 0.00 | 0.67 | 0.00 | 0.00 |
|
Showing page 105 |
first page | previous page | next page | last page |
Copyright © 2020 University of Pennsylvania. All Rights Reserved.