PDGs

 

The “druggable genome”, a term coined by Hopkins and Groom in 2002(3), defines a subset of genes in the human genome encoding proteins that may be amenable to modulation by drug-like molecules. To define potentially druggable genes (PDGs) in the human genome, we integrated the PDG candidates generated by six independent studies in which the druggable genes were systematically annotated by different strategies at a whole genome level. .

List of the PDGs in the human genome


 Show   entries each page
 Jump to page  

 Total Page: 305 Total entries: 6083
  
 Showing page 78  first page | previous page | next page | last page 
 
HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationTDLPubTator Score
phospholipase A2 group VIIENSG00000146070PLA2G7chr6:46704201-46735693:-Tchem783.439
coagulation factor II thrombin receptorENSG00000181104F2Rchr5:76716043-76735781:+Tclin701.277
fatty acid binding protein 1ENSG00000163586FABP1chr2:88122982-88128116:-Tchem294.815
WNT inhibitory factor 1ENSG00000156076WIF1chr12:65050626-65121566:-Tbio136.377
protein tyrosine phosphatase receptor type RENSG00000153233PTPRRchr12:70638073-70920843:-Tbio19.136
fibulin 1ENSG00000077942FBLN1chr22:45502238-45601135:+Tbio114.169
insulin like growth factor binding protein 2ENSG00000115457IGFBP2chr2:216632828-216664436:+Tchem462.748
prolyl endopeptidaseENSG00000085377PREPchr6:105277565-105403084:-Tchem470.214
glutathione S-transferase mu 3ENSG00000134202GSTM3chr1:109733932-109741038:-Tbio99.3634
zona pellucida glycoprotein 3ENSG00000188372ZP3chr7:76397518-76442071:+Tbio197.449
protein tyrosine phosphatase receptor type AENSG00000132670PTPRAchr20:2864184-3039076:+Tchem128.096
inhibitor of nuclear factor kappa B kinase regulatory subunit gammaENSG00000269335IKBKGchrX:154541199-154565046:+Tbio827.122
latent transforming growth factor beta binding protein 1ENSG00000049323LTBP1chr2:32946972-33399509:+Tbio71.6627
HCK proto-oncogene, Src family tyrosine kinaseENSG00000101336HCKchr20:32052188-32101856:+Tclin181.395
ribonuclease A family member 2ENSG00000169385RNASE2chr14:20955452-20956436:+Tchem299.96
corticotropin releasing hormone binding proteinENSG00000145708CRHBPchr5:76952713-76981158:+Tbio82.8393
arteminENSG00000117407ARTNchr1:43933320-43937241:+Tbio152.446
carbohydrate sulfotransferase 11ENSG00000171310CHST11chr12:104455295-104762014:+Tbio18.4813
sulfotransferase family 2A member 1ENSG00000105398SULT2A1chr19:47870466-47886397:-Tbio1161.59
deoxyribonuclease 1ENSG00000213918DNASE1chr16:3611728-3680143:+Tchem526.759

 Showing page 78  		first page | previous page | next page | last page 








Contact us | | Terms & Conditions.
Copyright © 2020 University of Pennsylvania. All Rights Reserved.