PDGs

 

The “druggable genome”, a term coined by Hopkins and Groom in 2002(3), defines a subset of genes in the human genome encoding proteins that may be amenable to modulation by drug-like molecules. To define potentially druggable genes (PDGs) in the human genome, we integrated the PDG candidates generated by six independent studies in which the druggable genes were systematically annotated by different strategies at a whole genome level. .

List of the PDGs in the human genome


 Show   entries each page
 Jump to page  

 Total Page: 305 Total entries: 6083
  
 Showing page 76  first page | previous page | next page | last page 
 
HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationTDLPubTator Score
semaphorin 3GENSG00000010319SEMA3Gchr3:52433053-52445085:-Tbio99.9136
carbonic anhydrase 14ENSG00000118298CA14chr1:150257159-150265078:+Tclin38.1425
proprotein convertase subtilisin/kexin type 5ENSG00000099139PCSK5chr9:75890644-76362339:+Tchem369.191
amyloid beta precursor like protein 2ENSG00000084234APLP2chr11:130069837-130144811:+Tbio84.1365
thyrotropin releasing hormoneENSG00000170893TRHchr3:129974305-129977938:+Tbio2496.65
hydroxysteroid 17-beta dehydrogenase 1ENSG00000108786HSD17B1chr17:42549214-42555213:+Tchem202.301
integrin subunit alpha 6ENSG00000091409ITGA6chr2:172427354-172506282:+Tbio210.451
myosin heavy chain 7ENSG00000092054MYH7chr14:23412738-23435718:-Tbio326.2
solute carrier family 29 member 4ENSG00000164638SLC29A4chr7:5274369-5306870:+Tbio51.7607
flavin containing dimethylaniline monoxygenase 3ENSG00000007933FMO3chr1:171090877-171117819:+Tbio216.609
cytochrome P450 family 1 subfamily A member 1ENSG00000140465CYP1A1chr15:74719542-74725610:-Tchem2390.39
4-hydroxyphenylpyruvate dioxygenaseENSG00000158104HPDchr12:121839527-121863596:-Tclin94.625
homeostatic iron regulatorENSG00000010704HFEchr6:26087281-26098343:+Tbio2117.84
proteasome 26S subunit, non-ATPase 7ENSG00000103035PSMD7chr16:74296775-74306288:+Tbio12.9895
peptidase, mitochondrial processing subunit alphaENSG00000165688PMPCAchr9:136410570-136423761:+Tbio6.33333
solute carrier family 22 member 5ENSG00000197375SLC22A5chr5:132369752-132395614:+Tbio232.709
purinergic receptor P2Y2ENSG00000175591P2RY2chr11:73218298-73236352:+Tclin261.972
tec protein tyrosine kinaseENSG00000135605TECchr4:48135783-48269864:-Tchem60.8418
ubiquitin like modifier activating enzyme 2ENSG00000126261UBA2chr19:34428352-34471251:+Tbio25.7615
STEAP family member 1ENSG00000164647STEAP1chr7:90154375-90164829:+Tbio35.579

 Showing page 76  		first page | previous page | next page | last page 








Contact us | | Terms & Conditions.
Copyright © 2020 University of Pennsylvania. All Rights Reserved.