TCDA PDG

  FCG

  Home

  PDGs

  Search

  Expression

  Copy Number

  Mutation

  Transcript Fusion

  Download

  Help

  About

PDGs

The “druggable genome”, a term coined by Hopkins and Groom in 2002(3), defines a subset of genes in the human genome encoding proteins that may be amenable to modulation by drug-like molecules. To define potentially druggable genes (PDGs) in the human genome, we integrated the PDG candidates generated by six independent studies in which the druggable genes were systematically annotated by different strategies at a whole genome level. .

List of the PDGs in the human genome

Show entries each page Jump to page Total Page: 305 Total entries: 6083
Showing page 69	first page \| previous page \| next page \| last page

HGNC Name	Ensembl Gene ID	HGNC Symbol	Genomic Location	TDL	PubTator Score
secretory leukocyte peptidase inhibitor	ENSG00000124107	SLPI	chr20:45252239-45254564:-	Tbio	486.584
CD248 molecule	ENSG00000174807	CD248	chr11:66314487-66317044:-	Tbio	309.265
ribosomal protein S6 kinase B1	ENSG00000108443	RPS6KB1	chr17:59893046-59950564:+	Tchem	796.599
integrin subunit alpha 2	ENSG00000164171	ITGA2	chr5:52989326-53094779:+	Tbio	292.995
ATPase Na+/K+ transporting subunit beta 1	ENSG00000143153	ATP1B1	chr1:169105697-169132722:+	Tclin	308.617
transforming growth factor beta receptor 3	ENSG00000069702	TGFBR3	chr1:91680343-91906335:-	Tbio	121.068
F11 receptor	ENSG00000158769	F11R	chr1:160995211-161021348:-	Tbio	1128.89
X-box binding protein 1	ENSG00000100219	XBP1	chr22:28794555-28800597:-	Tchem	457.145
CD48 molecule	ENSG00000117091	CD48	chr1:160678746-160711851:-	Tbio	151.982
X-linked inhibitor of apoptosis	ENSG00000101966	XIAP	chrX:123859724-123913979:+	Tchem	928.947
ABL proto-oncogene 2, non-receptor tyrosine kinase	ENSG00000143322	ABL2	chr1:179099327-179229684:-	Tchem	44.9301
urocortin	ENSG00000163794	UCN	chr2:27307400-27308445:-	Tbio	280.046
platelet derived growth factor subunit B	ENSG00000100311	PDGFB	chr22:39223359-39244751:-	Tchem	759.866
bone morphogenetic protein receptor type 2	ENSG00000204217	BMPR2	chr2:202376936-202567751:+	Tchem	624.08
serine/threonine kinase 33	ENSG00000130413	STK33	chr11:8391868-8594289:-	Tchem	9.90236
transient receptor potential cation channel subfamily M member 7	ENSG00000092439	TRPM7	chr15:50552473-50686815:-	Tbio	249.194
CEA cell adhesion molecule 1	ENSG00000079385	CEACAM1	chr19:42507304-42561234:-	Tbio	364.517
mitogen-activated protein kinase kinase kinase 2	ENSG00000169967	MAP3K2	chr2:127298730-127388465:-	Tchem	35.61
glutaredoxin 3	ENSG00000108010	GLRX3	chr10:130136399-130184521:+	Tbio	43.5417
collagen type VI alpha 2 chain	ENSG00000142173	COL6A2	chr21:46098097-46132849:+	Tbio	55.8098

Showing page 69

first page | previous page | next page | last page

  TCGA

  GDC

  NCI