PDGs

 

The “druggable genome”, a term coined by Hopkins and Groom in 2002(3), defines a subset of genes in the human genome encoding proteins that may be amenable to modulation by drug-like molecules. To define potentially druggable genes (PDGs) in the human genome, we integrated the PDG candidates generated by six independent studies in which the druggable genes were systematically annotated by different strategies at a whole genome level. .

List of the PDGs in the human genome


 Show   entries each page
 Jump to page  

 Total Page: 305 Total entries: 6083
  
 Showing page 56  first page | previous page | next page | last page 
 
HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationTDLPubTator Score
calcium voltage-gated channel subunit alpha1 CENSG00000151067CACNA1Cchr12:1970786-2697950:+Tclin422.678
interleukin 1 receptor type 2ENSG00000115590IL1R2chr2:101991844-102028544:+Tbio115.243
CART prepropeptideENSG00000164326CARTPTchr5:71719163-71721048:+Tbio383.412
ubiquitin specific peptidase 7ENSG00000187555USP7chr16:8892094-8964514:-Tchem135.437
transient receptor potential cation channel subfamily C member 1ENSG00000144935TRPC1chr3:142724074-142807888:+Tbio230.789
tripartite motif containing 28ENSG00000130726TRIM28chr19:58544091-58550722:+Tbio158.527
protein phosphatase 1 catalytic subunit alphaENSG00000172531PPP1CAchr11:67398183-67421183:-Tchem96.3729
SMAD family member 3ENSG00000166949SMAD3chr15:67063763-67195195:+Tbio687.769
C-X3-C motif chemokine ligand 1ENSG00000006210CX3CL1chr16:57372458-57385048:+Tbio373.228
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit betaENSG00000051382PIK3CBchr3:138652699-138834938:-Tchem110.701
luteinizing hormone subunit betaENSG00000104826LHBchr19:49015980-49017090:-Tbio324.399
phospholipase C beta 1ENSG00000182621PLCB1chr20:8114453-8968360:+Tbio381.349
alkaline phosphatase, biomineralization associatedENSG00000162551ALPLchr1:21509372-21578412:+Tchem273.818
cytochrome P450 family 3 subfamily A member 7ENSG00000160870CYP3A7chr7:99705037-99735196:-Tclin155.212
CD63 moleculeENSG00000135404CD63chr12:55725323-55729707:-Tbio565.74
solute carrier family 52 member 3ENSG00000101276SLC52A3chr20:760080-776015:-Tbio57.254
PHD finger protein 7ENSG00000010318PHF7chr3:52410561-52423641:+Tdark4.625
lactate dehydrogenase BENSG00000111716LDHBchr12:21635342-21757857:-Tchem151.174
alpha 2-HS glycoproteinENSG00000145192AHSGchr3:186612923-186621318:+Tbio729.013
cellular communication network factor 4ENSG00000104415WISP1chr8:133191039-133230344:+Tbio70.0523

 Showing page 56  		first page | previous page | next page | last page 








Contact us | | Terms & Conditions.
Copyright © 2020 University of Pennsylvania. All Rights Reserved.