PDGs

 

The “druggable genome”, a term coined by Hopkins and Groom in 2002(3), defines a subset of genes in the human genome encoding proteins that may be amenable to modulation by drug-like molecules. To define potentially druggable genes (PDGs) in the human genome, we integrated the PDG candidates generated by six independent studies in which the druggable genes were systematically annotated by different strategies at a whole genome level. .

List of the PDGs in the human genome


 Show   entries each page
 Jump to page  

 Total Page: 305 Total entries: 6083
  
 Showing page 54  first page | previous page | next page | last page 
 
HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationTDLPubTator Score
MAPK activated protein kinase 2ENSG00000162889MAPKAPK2chr1:206684944-206734283:+Tchem280.018
fucosyltransferase 1 (H blood group)ENSG00000174951FUT1chr19:48748011-48755390:-Tbio224.994
serine protease 1ENSG00000204983PRSS1chr7:142749468-142763997:+Tclin404.644
collagen type IV alpha 5 chainENSG00000188153COL4A5chrX:108439844-108697545:+Tbio285.05
coagulation factor VIIENSG00000057593F7chr13:113105788-113120681:+Tchem338.259
DM1 protein kinaseENSG00000104936DMPKchr19:45769717-45782552:-Tchem1097.27
PVR cell adhesion moleculeENSG00000073008PVRchr19:44643798-44663583:+Tbio308.754
CXXC finger protein 1ENSG00000154832CXXC1chr18:50282343-50288304:-Tbio23.8804
adrenoceptor alpha 2AENSG00000150594ADRA2Achr10:111077163-111080907:+Tclin350.229
methionine adenosyltransferase 1AENSG00000151224MAT1Achr10:80271820-80289684:-Tbio435.345
LDL receptor related protein 1ENSG00000123384LRP1chr12:57128493-57213351:+Tbio843.34
myostatinENSG00000138379MSTNchr2:190055697-190062729:-Tbio335.942
butyrylcholinesteraseENSG00000114200BCHEchr3:165772904-165837472:-Tclin1889.11
chromobox 7ENSG00000100307CBX7chr22:39120167-39152674:-Tchem28.1929
integrin subunit beta 4ENSG00000132470ITGB4chr17:75721328-75757818:+Tbio134.654
semaphorin 3FENSG00000001617SEMA3Fchr3:50155045-50189075:+Tbio57.963
nuclear receptor subfamily 1 group H member 4ENSG00000012504NR1H4chr12:100473708-100564413:+Tclin566.769
myelin associated glycoproteinENSG00000105695MAGchr19:35292125-35313804:+Tchem567.926
potassium calcium-activated channel subfamily M alpha 1ENSG00000156113KCNMA1chr10:76869601-77638595:-Tclin306.078
neuronal pentraxin 2ENSG00000106236NPTX2chr7:98617297-98629868:+Tbio134.58

 Showing page 54  		first page | previous page | next page | last page 








Contact us | | Terms & Conditions.
Copyright © 2020 University of Pennsylvania. All Rights Reserved.