TCDA PDG

  FCG

  Home

  PDGs

  Search

  Expression

  Copy Number

  Mutation

  Transcript Fusion

  Download

  Help

  About

PDGs

The “druggable genome”, a term coined by Hopkins and Groom in 2002(3), defines a subset of genes in the human genome encoding proteins that may be amenable to modulation by drug-like molecules. To define potentially druggable genes (PDGs) in the human genome, we integrated the PDG candidates generated by six independent studies in which the druggable genes were systematically annotated by different strategies at a whole genome level. .

List of the PDGs in the human genome

Show entries each page Jump to page Total Page: 305 Total entries: 6083
Showing page 47	first page \| previous page \| next page \| last page

HGNC Name	Ensembl Gene ID	HGNC Symbol	Genomic Location	TDL	PubTator Score
cathepsin D	ENSG00000117984	CTSD	chr11:1752752-1763992:-	Tchem	1805.44
serine protease 21	ENSG00000007038	PRSS21	chr16:2817180-2826304:+	Tbio	511.874
von Willebrand factor	ENSG00000110799	VWF	chr12:5948874-6124770:-	Tbio	5448.68
phospholipase A2 group IB	ENSG00000170890	PLA2G1B	chr12:120322111-120327789:-	Tchem	350.04
mucin 5B, oligomeric mucus/gel-forming	ENSG00000117983	MUC5B	chr11:1223066-1262172:+	Tbio	495.014
inhibitor of nuclear factor kappa B kinase subunit epsilon	ENSG00000263528	IKBKE	chr1:206470476-206496889:+	Tchem	70.65
indoleamine 2,3-dioxygenase 1	ENSG00000131203	IDO1	chr8:39902275-39928444:+	Tchem	835.825
glucosylceramidase beta	ENSG00000177628	GBA	chr1:155234452-155244699:-	Tchem	904.091
complement C3d receptor 2	ENSG00000117322	CR2	chr1:207454230-207489895:+	Tbio	1018.6
cytochrome P450 family 21 subfamily A member 2	ENSG00000231852	CYP21A2	chr6:32038265-32041670:+	Tbio	1037
C-X-C motif chemokine receptor 4	ENSG00000121966	CXCR4	chr2:136114349-136118165:-	Tclin	3388.38
peripheral myelin protein 22	ENSG00000109099	PMP22	chr17:15229777-15265326:-	Tbio	606.91
ATPase H+ transporting V1 subunit B2	ENSG00000147416	ATP6V1B2	chr8:20197367-20226819:+	Tbio	10.8909
secretin	ENSG00000070031	SCT	chr11:626431-627143:-	Tbio	966.731
follistatin	ENSG00000134363	FST	chr5:53480409-53487134:+	Tbio	189.575
ribophorin II	ENSG00000118705	RPN2	chr20:37178410-37241623:+	Tbio	32.277
EBP cholestenol delta-isomerase	ENSG00000147155	EBP	chrX:48521158-48528716:+	Tchem	477.774
dopamine receptor D4	ENSG00000069696	DRD4	chr11:637293-640706:+	Tchem	1219.26
solute carrier family 18 member A2	ENSG00000165646	SLC18A2	chr10:117241093-117279430:+	Tclin	325.509
TNF superfamily member 13b	ENSG00000102524	TNFSF13B	chr13:108251240-108308484:+	Tclin	896.944

Showing page 47

first page | previous page | next page | last page

  TCGA

  GDC

  NCI