TCDA PDG

  FCG

  Home

  PDGs

  Search

  Expression

  Copy Number

  Mutation

  Transcript Fusion

  Download

  Help

  About

PDGs

The “druggable genome”, a term coined by Hopkins and Groom in 2002(3), defines a subset of genes in the human genome encoding proteins that may be amenable to modulation by drug-like molecules. To define potentially druggable genes (PDGs) in the human genome, we integrated the PDG candidates generated by six independent studies in which the druggable genes were systematically annotated by different strategies at a whole genome level. .

List of the PDGs in the human genome

Show entries each page Jump to page Total Page: 305 Total entries: 6083
Showing page 36	first page \| previous page \| next page \| last page

HGNC Name	Ensembl Gene ID	HGNC Symbol	Genomic Location	TDL	PubTator Score
aldehyde dehydrogenase 1 family member A1	ENSG00000165092	ALDH1A1	chr9:72900662-73080442:-	Tchem	484.085
neuregulin 1	ENSG00000157168	NRG1	chr8:31639386-32767959:+	Tbio	761.384
interleukin 1 receptor antagonist	ENSG00000136689	IL1RN	chr2:113107214-113134016:+	Tchem	1969.46
synuclein alpha	ENSG00000145335	SNCA	chr4:89724099-89838315:-	Tchem	4085.42
TNF receptor superfamily member 11b	ENSG00000164761	TNFRSF11B	chr8:118923557-118952200:-	Tbio	1674.02
MOK protein kinase	ENSG00000080823	MOK	chr14:102224500-102305200:-	Tbio	67.179
potassium voltage-gated channel subfamily H member 2	ENSG00000055118	KCNH2	chr7:150944961-150978315:-	Tclin	1373.24
arachidonate 5-lipoxygenase	ENSG00000012779	ALOX5	chr10:45374176-45446119:+	Tclin	1830.01
collagen type II alpha 1 chain	ENSG00000139219	COL2A1	chr12:47972965-48004486:-	Tbio	619.52
paraoxonase 1	ENSG00000005421	PON1	chr7:95297676-95324707:-	Tbio	2476.13
jade family PHD finger 1	ENSG00000077684	JADE1	chr4:128809623-128875224:+	Tbio	9.92806
SRC proto-oncogene, non-receptor tyrosine kinase	ENSG00000197122	SRC	chr20:37344685-37406050:+	Tclin	3297.81
myeloperoxidase	ENSG00000005381	MPO	chr17:58269856-58280935:-	Tchem	5596.63
protein tyrosine phosphatase non-receptor type 13	ENSG00000163629	PTPN13	chr4:86594315-86815171:+	Tchem	162.58
endothelin 1	ENSG00000078401	EDN1	chr6:12290363-12297194:+	Tbio	5752.9
macrophage stimulating 1 receptor	ENSG00000164078	MST1R	chr3:49887002-49903873:-	Tchem	348.333
secreted protein acidic and cysteine rich	ENSG00000113140	SPARC	chr5:151661096-151687165:-	Tbio	714.669
cellular communication network factor 2	ENSG00000118523	CTGF	chr6:131948176-131951373:-	Tbio	997.747
haptoglobin-related protein	ENSG00000261701	HPR	chr16:72063224-72077246:+	Tbio	294.845
triggering receptor expressed on myeloid cells 1	ENSG00000124731	TREM1	chr6:41267926-41286719:-	Tbio	206.106

Showing page 36

first page | previous page | next page | last page

  TCGA

  GDC

  NCI