TCDA PDG

  FCG

  Home

  PDGs

  Search

  Expression

  Copy Number

  Mutation

  Transcript Fusion

  Download

  Help

  About

PDGs

The “druggable genome”, a term coined by Hopkins and Groom in 2002(3), defines a subset of genes in the human genome encoding proteins that may be amenable to modulation by drug-like molecules. To define potentially druggable genes (PDGs) in the human genome, we integrated the PDG candidates generated by six independent studies in which the druggable genes were systematically annotated by different strategies at a whole genome level. .

List of the PDGs in the human genome

Show entries each page Jump to page Total Page: 305 Total entries: 6083
Showing page 25	first page \| previous page \| next page \| last page

HGNC Name	Ensembl Gene ID	HGNC Symbol	Genomic Location	TDL	PubTator Score
7-dehydrocholesterol reductase	ENSG00000172893	DHCR7	chr11:71428193-71452868:-	Tchem	198.417
KiSS-1 metastasis suppressor	ENSG00000170498	KISS1	chr1:204190341-204196486:-	Tbio	335.259
transketolase	ENSG00000163931	TKT	chr3:53224707-53256052:-	Tchem	534.05
CD33 molecule	ENSG00000105383	CD33	chr19:51225064-51243860:+	Tclin	888.121
TIMP metallopeptidase inhibitor 1	ENSG00000102265	TIMP1	chrX:47582313-47586789:+	Tbio	2273.4
cholecystokinin	ENSG00000187094	CCK	chr3:42257825-42266207:-	Tbio	2246.82
cholinergic receptor nicotinic alpha 3 subunit	ENSG00000080644	CHRNA3	chr15:78593052-78621295:-	Tclin	110.742
insulin	ENSG00000254647	INS	chr11:2159779-2161341:-	Tbio	51392.5
vasoactive intestinal peptide	ENSG00000146469	VIP	chr6:152750798-152759765:+	Tbio	3173.44
proprotein convertase subtilisin/kexin type 9	ENSG00000169174	PCSK9	chr1:55039548-55064852:+	Tclin	891.424
neural cell adhesion molecule 1	ENSG00000149294	NCAM1	chr11:112961247-113278436:+	Tbio	2790.29
solute carrier family 19 member 1	ENSG00000173638	SLC19A1	chr21:45493572-45544411:-	Tchem	217.804
protein tyrosine phosphatase receptor type N2	ENSG00000155093	PTPRN2	chr7:157539056-158587788:-	Tbio	51.1765
DEAD-box helicase 3 X-linked	ENSG00000215301	DDX3X	chrX:41333348-41364472:+	Tchem	122.253
angiopoietin 1	ENSG00000154188	ANGPT1	chr8:107249482-107498055:-	Tbio	543.786
cyclin dependent kinase inhibitor 1A	ENSG00000124762	CDKN1A	chr6:36676460-36687339:+	Tbio	3747.94
C-C motif chemokine ligand 17	ENSG00000102970	CCL17	chr16:57404767-57416062:+	Tbio	273.545
intercellular adhesion molecule 1	ENSG00000090339	ICAM1	chr19:10270835-10286615:+	Tchem	5040.32
GLI family zinc finger 2	ENSG00000074047	GLI2	chr2:120735623-120992653:+	Tchem	2335.66
plasminogen activator, urokinase receptor	ENSG00000011422	PLAUR	chr19:43646095-43670547:-	Tchem	1013.73

Showing page 25

first page | previous page | next page | last page

  TCGA

  GDC

  NCI