PDGs

 

The “druggable genome”, a term coined by Hopkins and Groom in 2002(3), defines a subset of genes in the human genome encoding proteins that may be amenable to modulation by drug-like molecules. To define potentially druggable genes (PDGs) in the human genome, we integrated the PDG candidates generated by six independent studies in which the druggable genes were systematically annotated by different strategies at a whole genome level. .

List of the PDGs in the human genome


 Show   entries each page
 Jump to page  

 Total Page: 305 Total entries: 6083
  
 Showing page 248  first page | previous page | next page | last page 
 
HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationTDLPubTator Score
secreted phosphoprotein 2ENSG00000072080SPP2chr2:234050679-234077134:+Tbio26.2214
major facilitator superfamily domain containing 11ENSG00000092931MFSD11chr17:76735865-76781449:+Tdark0
histone deacetylase 8ENSG00000147099HDAC8chrX:72329516-72573103:-Tclin152.18
abhydrolase domain containing 16A, phospholipaseENSG00000204427ABHD16Achr6:31686949-31703444:-Tchem5.23645
proteasome subunit beta 11ENSG00000222028PSMB11chr14:23042167-23044276:+Tbio2.91667
SET domain containing 1B, histone lysine methyltransferaseENSG00000139718SETD1Bchr12:121804180-121832584:+Tbio10.2544
phosphatidylinositol 4-kinase type 2 alphaENSG00000155252PI4K2Achr10:97640686-97676434:+Tbio15.7167
dual specificity phosphatase 11ENSG00000144048DUSP11chr2:73762184-73780157:-Tbio15.325
protein O-glucosyltransferase 1ENSG00000163389POGLUT1chr3:119468938-119494708:+Tbio29.3167
phosphatidylinositol glycan anchor biosynthesis class KENSG00000142892PIGKchr1:77088990-77219430:-Tbio16.7
pro-melanin concentrating hormoneENSG00000183395PMCHchr12:102196459-102197845:-Tbio865.556
chorionic somatomammotropin hormone like 1ENSG00000204414CSHL1chr17:63909597-63918838:-Tbio286.17
MT-RNR2 like 8ENSG00000255823MTRNR2L8chr11:10507887-10509189:-Tdark0
microsomal glutathione S-transferase 2ENSG00000085871MGST2chr4:139665768-139740745:+Tbio13.7881
solute carrier family 30 member 5ENSG00000145740SLC30A5chr5:69093646-69131069:+Tbio16.9409
taste 2 receptor member 10ENSG00000121318TAS2R10chr12:10825317-10826358:-Tbio8.20833
desert hedgehog signaling moleculeENSG00000139549DHHchr12:49089421-49094819:-Tbio48.5155
cyclin dependent kinase 3ENSG00000250506CDK3chr17:76000906-76005999:+Tchem22.8663
ubiquitin specific peptidase 47ENSG00000170242USP47chr11:11841423-11959323:+Tchem3.59286
mannosidase alpha class 2B member 2ENSG00000013288MAN2B2chr4:6575175-6623362:+Tdark5.86667

 Showing page 248  		first page | previous page | next page | last page 








Contact us | | Terms & Conditions.
Copyright © 2020 University of Pennsylvania. All Rights Reserved.