PDGs

 

The “druggable genome”, a term coined by Hopkins and Groom in 2002(3), defines a subset of genes in the human genome encoding proteins that may be amenable to modulation by drug-like molecules. To define potentially druggable genes (PDGs) in the human genome, we integrated the PDG candidates generated by six independent studies in which the druggable genes were systematically annotated by different strategies at a whole genome level. .

List of the PDGs in the human genome


 Show   entries each page
 Jump to page  

 Total Page: 305 Total entries: 6083
  
 Showing page 245  first page | previous page | next page | last page 
 
HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationTDLPubTator Score
RIO kinase 3ENSG00000101782RIOK3chr18:23452823-23486603:+Tchem9.82617
ciliogenesis associated kinase 1ENSG00000112144ICKchr6:53001279-53061802:-Tchem40.4675
kelch like family member 20ENSG00000076321KLHL20chr1:173714941-173786702:+Tbio7.07063
5-hydroxytryptamine receptor 1BENSG00000135312HTR1Bchr6:77462205-77463464:-Tclin591.087
vitamin K epoxide reductase complex subunit 1 like 1ENSG00000196715VKORC1L1chr7:65873267-65959563:+Tbio7.25
activin A receptor type 1CENSG00000123612ACVR1Cchr2:157526767-157629005:-Tbio29.4
chymotrypsin like elastase 3BENSG00000219073CELA3Bchr1:21977021-21998642:+Tbio162.304
carboxypeptidase ZENSG00000109625CPZchr4:8592660-8619759:+Tdark23.9
mitogen-activated protein kinase kinase kinase kinase 5ENSG00000012983MAP4K5chr14:50418501-50561126:-Tchem8.50516
tripartite motif containing 39ENSG00000204599TRIM39chr6:30326479-30343729:+Tbio7.81667
solute carrier family 9 member C1ENSG00000172139SLC9C1chr3:112140887-112294258:-Tdark261.326
solute carrier family 35 member A3ENSG00000117620SLC35A3chr1:99969789-100026979:+Tbio11.3333
solute carrier family 2 member 14ENSG00000173262SLC2A14chr12:7812512-7891148:-Tbio8.94954
dopamine receptor D5ENSG00000169676DRD5chr4:9781680-9784009:+Tchem136.587
solute carrier family 35 member F5ENSG00000115084SLC35F5chr2:113705011-113756823:-Tdark0.787301
thioredoxin domain containing 15ENSG00000113621TXNDC15chr5:134873803-134901525:+Tdark33.8274
prenylcysteine oxidase 1ENSG00000116005PCYOX1chr2:70257386-70281191:+Tbio8.975
complement C1q C chainENSG00000159189C1QCchr1:22643630-22648110:+Tbio11.4444
PHD finger protein 6ENSG00000156531PHF6chrX:134373253-134428791:+Tbio69.2421
endoplasmic reticulum protein 44ENSG00000023318ERP44chr9:99979179-100099040:-Tbio29.025

 Showing page 245  		first page | previous page | next page | last page 








Contact us | | Terms & Conditions.
Copyright © 2020 University of Pennsylvania. All Rights Reserved.