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PDGs

The “druggable genome”, a term coined by Hopkins and Groom in 2002(3), defines a subset of genes in the human genome encoding proteins that may be amenable to modulation by drug-like molecules. To define potentially druggable genes (PDGs) in the human genome, we integrated the PDG candidates generated by six independent studies in which the druggable genes were systematically annotated by different strategies at a whole genome level. .

List of the PDGs in the human genome

Show entries each page Jump to page Total Page: 305 Total entries: 6083
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HGNC Name	Ensembl Gene ID	HGNC Symbol	Genomic Location	TDL	PubTator Score
caspase recruitment domain family member 17	ENSG00000255221	CARD17	chr11:105092469-105101431:-	Tbio	0.25
PHD and ring finger domains 1	ENSG00000070047	PHRF1	chr11:576486-612222:+	Tbio	3.28333
xylosyltransferase 1	ENSG00000103489	XYLT1	chr16:17101769-17470881:-	Tbio	50.3595
C-C motif chemokine receptor like 2	ENSG00000121797	CCRL2	chr3:46407163-46412997:+	Tchem	100.5
NIMA related kinase 8	ENSG00000160602	NEK8	chr17:28725897-28743455:+	Tbio	27.771
adenosine deaminase like	ENSG00000168803	ADAL	chr15:43330674-43354555:+	Tbio	6.43333
clusterin like 1	ENSG00000079101	CLUL1	chr18:596988-650334:+	Tdark	2.16667
dehydrogenase/reductase X-linked	ENSG00000169084	DHRSX	chrX:2219516-2502805:-	Tdark	2.30119
solute carrier family 17 member 1	ENSG00000124568	SLC17A1	chr6:25782897-25832059:-	Tbio	51.6913
RAN binding protein 9	ENSG00000010017	RANBP9	chr6:13621498-13711564:-	Tbio	54.6814
acrosin	ENSG00000100312	ACR	chr22:50738196-50745334:+	Tchem	1106.45
zinc binding alcohol dehydrogenase domain containing 2	ENSG00000180011	ZADH2	chr18:75195108-75209348:-	Tbio	2.075
solute carrier family 18 member B1	ENSG00000146409	SLC18B1	chr6:132769370-132798553:-	Tdark	3.25
proteasome 20S subunit beta 10	ENSG00000205220	PSMB10	chr16:67934502-67937087:-	Tchem	38.2773
interleukin 17 receptor E	ENSG00000163701	IL17RE	chr3:9902612-9916402:+	Tdark	6.26246
proline rich 4	ENSG00000111215	PRR4	chr12:10845849-11171613:-	Tbio	15.1317
glucosidase II alpha subunit	ENSG00000089597	GANAB	chr11:62624826-62646726:-	Tchem	3.76667
tripartite motif containing 24	ENSG00000122779	TRIM24	chr7:138460334-138589993:+	Tchem	65.9033
CDC42 binding protein kinase alpha	ENSG00000143776	CDC42BPA	chr1:226989865-227318474:-	Tchem	26.4212
5-hydroxytryptamine receptor 7	ENSG00000148680	HTR7	chr10:90740823-90857698:-	Tclin	44.982

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