PDGs

 

The “druggable genome”, a term coined by Hopkins and Groom in 2002(3), defines a subset of genes in the human genome encoding proteins that may be amenable to modulation by drug-like molecules. To define potentially druggable genes (PDGs) in the human genome, we integrated the PDG candidates generated by six independent studies in which the druggable genes were systematically annotated by different strategies at a whole genome level. .

List of the PDGs in the human genome


 Show   entries each page
 Jump to page  

 Total Page: 305 Total entries: 6083
  
 Showing page 178  first page | previous page | next page | last page 
 
HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationTDLPubTator Score
G protein-coupled receptor 141ENSG00000187037GPR141chr7:37683796-37833788:+Tdark0.507936
CD53 moleculeENSG00000143119CD53chr1:110873154-110899928:+Tbio452.391
solute carrier family 22 member 7ENSG00000137204SLC22A7chr6:43295694-43305538:+Tbio40.5242
capping actin protein of muscle Z-line subunit alpha 2ENSG00000198898CAPZA2chr7:116811070-116922049:+Tdark25.9552
hydroxysteroid 11-beta dehydrogenase 1 likeENSG00000167733HSD11B1Lchr19:5680604-5688523:+Tdark17.2333
dipeptidase 2ENSG00000167261DPEP2chr16:67987394-68000586:-Tdark0.811111
ASXL transcriptional regulator 1ENSG00000171456ASXL1chr20:32358344-32439319:+Tbio120.935
transmembrane protein 25ENSG00000149582TMEM25chr11:118531041-118547280:+Tdark2.88597
orosomucoid 2ENSG00000228278ORM2chr9:114329869-114333252:+Tbio48.6313
serpin family B member 8ENSG00000166401SERPINB8chr18:63969925-64005667:+Tbio18.1474
purinergic receptor P2X 5ENSG00000083454P2RX5chr17:3672199-3696404:-Tbio32.5811
heat shock protein family A (Hsp70) member 1AENSG00000204389HSPA1Achr6:31815464-31817946:+Tbio112.803
protein tyrosine phosphatase non-receptor type 21ENSG00000070778PTPN21chr14:88465778-88554733:-Tbio12.6012
solute carrier family 2 member 11ENSG00000133460SLC2A11chr22:23856703-23886309:+Tdark11.4694
thrombospondin type 1 domain containing 4ENSG00000187720THSD4chr15:71096952-71783383:+Tdark3.84785
collagen type XXV alpha 1 chainENSG00000188517COL25A1chr4:108810721-109302657:-Tbio26.3333
poly(ADP-ribose) polymerase family member 14ENSG00000173193PARP14chr3:122680618-122730840:+Tbio201.174
interferon alpha and beta receptor subunit 2ENSG00000159110IFNAR2chr21:33229901-33265675:+Tclin98.3074
ribonuclease A family member 7ENSG00000165799RNASE7chr14:21042226-21044234:+Tbio40.0346
solute carrier family 6 member 20ENSG00000163817SLC6A20chr3:45755450-45796535:-Tbio11.4849

 Showing page 178  		first page | previous page | next page | last page 








Contact us | | Terms & Conditions.
Copyright © 2020 University of Pennsylvania. All Rights Reserved.