PDGs

 

The “druggable genome”, a term coined by Hopkins and Groom in 2002(3), defines a subset of genes in the human genome encoding proteins that may be amenable to modulation by drug-like molecules. To define potentially druggable genes (PDGs) in the human genome, we integrated the PDG candidates generated by six independent studies in which the druggable genes were systematically annotated by different strategies at a whole genome level. .

List of the PDGs in the human genome


 Show   entries each page
 Jump to page  

 Total Page: 305 Total entries: 6083
  
 Showing page 172  first page | previous page | next page | last page 
 
HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationTDLPubTator Score
myosin IIIAENSG00000095777MYO3Achr10:25934267-26212527:+Tbio23.5103
tau tubulin kinase 2ENSG00000128881TTBK2chr15:42738734-42920809:-Tbio18.8776
coactivator associated arginine methyltransferase 1ENSG00000142453CARM1chr19:10871513-10923070:+Tchem113.666
thyrotropin releasing hormone degrading enzymeENSG00000072657TRHDEchr12:72087266-72670757:+Tbio35.0671
solute carrier family 25 member 5ENSG00000005022SLC25A5chrX:119468400-119471319:+Tbio728.416
solute carrier family 25 member 18ENSG00000182902SLC25A18chr22:17563439-17590994:+Tdark83.7861
potassium sodium-activated channel subfamily T member 2ENSG00000162687KCNT2chr1:196225779-196609225:-Tchem15.3623
SPARC related modular calcium binding 2ENSG00000112562SMOC2chr6:168441151-168673445:+Tbio17.7548
dual specificity phosphatase 23ENSG00000158716DUSP23chr1:159780932-159782543:+Tbio18.879
elastin microfibril interfacer 3ENSG00000183798EMILIN3chr20:41359966-41366827:-Tdark3.95
ATPase plasma membrane Ca2+ transporting 4ENSG00000058668ATP2B4chr1:203626561-203744081:+Tbio102.712
cation channel sperm associated 1ENSG00000175294CATSPER1chr11:66016752-66026517:-Tchem48.9547
PR/SET domain 14ENSG00000147596PRDM14chr8:70051651-70071693:-Tbio23.2309
neuromedin U receptor 1ENSG00000171596NMUR1chr2:231523160-231530495:-Tchem49.6289
EPH receptor A8ENSG00000070886EPHA8chr1:22563564-22603594:+Tchem69.9753
potassium voltage-gated channel modifier subfamily F member 1ENSG00000162975KCNF1chr2:10911937-10914225:+Tclin21.681
serine protease 22ENSG00000005001PRSS22chr16:2852727-2858170:-Tdark5.91667
C-C motif chemokine ligand 24ENSG00000106178CCL24chr7:75811665-75823356:-Tbio73.7283
calcium voltage-gated channel subunit alpha1 IENSG00000100346CACNA1Ichr22:39570753-39689737:+Tclin25.783
taste 2 receptor member 14ENSG00000212127TAS2R14chr12:10937406-11171573:-Tbio26.3012

 Showing page 172  		first page | previous page | next page | last page 








Contact us | | Terms & Conditions.
Copyright © 2020 University of Pennsylvania. All Rights Reserved.