TCDA PDG

  FCG

  Home

  PDGs

  Search

  Expression

  Copy Number

  Mutation

  Transcript Fusion

  Download

  Help

  About

PDGs

The “druggable genome”, a term coined by Hopkins and Groom in 2002(3), defines a subset of genes in the human genome encoding proteins that may be amenable to modulation by drug-like molecules. To define potentially druggable genes (PDGs) in the human genome, we integrated the PDG candidates generated by six independent studies in which the druggable genes were systematically annotated by different strategies at a whole genome level. .

List of the PDGs in the human genome

Show entries each page Jump to page Total Page: 305 Total entries: 6083
Showing page 16	first page \| previous page \| next page \| last page

HGNC Name	Ensembl Gene ID	HGNC Symbol	Genomic Location	TDL	PubTator Score
adenosylhomocysteinase	ENSG00000101444	AHCY	chr20:34280268-34311802:-	Tchem	235.792
cytochrome P450 family 3 subfamily A member 4	ENSG00000160868	CYP3A4	chr7:99756960-99784265:-	Tclin	4568.75
toll like receptor 4	ENSG00000136869	TLR4	chr9:117704332-117716871:+	Tchem	3527.81
protein kinase C theta	ENSG00000065675	PRKCQ	chr10:6427143-6580301:-	Tchem	96.0306
phenylethanolamine N-methyltransferase	ENSG00000141744	PNMT	chr17:39667981-39670475:+	Tchem	313.63
RELB proto-oncogene, NF-kB subunit	ENSG00000104856	RELB	chr19:45001430-45038198:+	Tbio	153.634
S100 calcium binding protein A8	ENSG00000143546	S100A8	chr1:153390032-153391188:-	Tbio	1201.88
lysozyme	ENSG00000090382	LYZ	chr12:69348341-69354234:+	Tbio	3490.76
talin 1	ENSG00000137076	TLN1	chr9:35696948-35732395:-	Tbio	58.6472
dual specificity phosphatase 1	ENSG00000120129	DUSP1	chr5:172768090-172771195:-	Tchem	327.888
interleukin 1 receptor type 1	ENSG00000115594	IL1R1	chr2:102064544-102179874:+	Tclin	385.271
plasminogen activator, tissue type	ENSG00000104368	PLAT	chr8:42175233-42207724:-	Tclin	3070.49
CD38 molecule	ENSG00000004468	CD38	chr4:15778275-15853230:+	Tclin	1601.95
axin 2	ENSG00000168646	AXIN2	chr17:65528563-65561647:-	Tchem	149.723
cyclin dependent kinase 9	ENSG00000136807	CDK9	chr9:127785679-127790787:+	Tchem	371.197
serpin family A member 1	ENSG00000197249	SERPINA1	chr14:94376747-94390693:-	Tbio	2342.79
growth differentiation factor 15	ENSG00000130513	GDF15	chr19:18374731-18389176:+	Tbio	615.007
interleukin 2 receptor subunit gamma	ENSG00000147168	IL2RG	chrX:71107404-71112108:-	Tclin	372.618
heat shock protein family A (Hsp70) member 5	ENSG00000044574	HSPA5	chr9:125234853-125241330:-	Tchem	1221.66
endoplasmic reticulum to nucleus signaling 1	ENSG00000178607	ERN1	chr17:64039142-64130819:-	Tchem	316.849

Showing page 16

first page | previous page | next page | last page

  TCGA

  GDC

  NCI