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PDGs

The “druggable genome”, a term coined by Hopkins and Groom in 2002(3), defines a subset of genes in the human genome encoding proteins that may be amenable to modulation by drug-like molecules. To define potentially druggable genes (PDGs) in the human genome, we integrated the PDG candidates generated by six independent studies in which the druggable genes were systematically annotated by different strategies at a whole genome level. .

List of the PDGs in the human genome

Show entries each page Jump to page Total Page: 305 Total entries: 6083
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HGNC Name	Ensembl Gene ID	HGNC Symbol	Genomic Location	TDL	PubTator Score
adhesion G protein-coupled receptor G6	ENSG00000112414	ADGRG6	chr6:142301854-142446266:+	Tbio	16.7457
latent transforming growth factor beta binding protein 2	ENSG00000119681	LTBP2	chr14:74498170-74612378:-	Tbio	55.4075
chromodomain helicase DNA binding protein 1	ENSG00000153922	CHD1	chr5:98853985-98928957:-	Tbio	61.2057
contactin associated protein 1	ENSG00000108797	CNTNAP1	chr17:42682613-42699814:+	Tbio	129.565
solute carrier family 5 member 6	ENSG00000138074	SLC5A6	chr2:27199587-27212958:-	Tbio	61.0024
solute carrier family 38 member 3	ENSG00000188338	SLC38A3	chr3:50205246-50221486:+	Tbio	210.709
cholecystokinin B receptor	ENSG00000110148	CCKBR	chr11:6259736-6272127:+	Tclin	462.426
olfactomedin like 1	ENSG00000183801	OLFML1	chr11:7485388-7511377:+	Tdark	2.06667
gastric inhibitory polypeptide receptor	ENSG00000010310	GIPR	chr19:45668244-45683724:+	Tchem	59.9863
solute carrier family 2 member 10	ENSG00000197496	SLC2A10	chr20:46709487-46736347:+	Tbio	37.6578
FKBP prolyl isomerase 1A	ENSG00000088832	FKBP1A	chr20:1368978-1393172:-	Tclin	173.308
solute carrier family 7 member 3	ENSG00000165349	SLC7A3	chrX:70925582-70931125:-	Tbio	31.3452
solute carrier family 4 member 2	ENSG00000164889	SLC4A2	chr7:151057210-151076527:+	Tbio	95.8662
pancreatic lipase related protein 3	ENSG00000203837	PNLIPRP3	chr10:116427867-116477957:+	Tdark	1
casein kinase 1 epsilon	ENSG00000213923	CSNK1E	chr22:38290691-38398522:-	Tchem	48.6015
peptidase domain containing associated with muscle regeneration 1	ENSG00000149090	PAMR1	chr11:35431823-35530300:-	Tdark	47.0667
vesicle amine transport 1 like	ENSG00000171724	VAT1L	chr16:77788530-77980107:+	Tdark	0.166667
frizzled class receptor 8	ENSG00000177283	FZD8	chr10:35638249-35642278:-	Tbio	18.7107
solute carrier family 2 member 5	ENSG00000142583	SLC2A5	chr1:9035107-9088478:-	Tbio	113.549
myosin light chain kinase family member 4	ENSG00000145949	MYLK4	chr6:2663629-2750966:-	Tchem	0.833333

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