PDGs

 

The “druggable genome”, a term coined by Hopkins and Groom in 2002(3), defines a subset of genes in the human genome encoding proteins that may be amenable to modulation by drug-like molecules. To define potentially druggable genes (PDGs) in the human genome, we integrated the PDG candidates generated by six independent studies in which the druggable genes were systematically annotated by different strategies at a whole genome level. .

List of the PDGs in the human genome


 Show   entries each page
 Jump to page  

 Total Page: 305 Total entries: 6083
  
 Showing page 154  first page | previous page | next page | last page 
 
HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationTDLPubTator Score
dentin matrix acidic phosphoprotein 1ENSG00000152592DMP1chr4:87650307-87664361:+Tbio181.322
interleukin 20 receptor subunit betaENSG00000174564IL20RBchr3:136946230-137011085:+Tbio15.3555
integrin subunit beta 8ENSG00000105855ITGB8chr7:20330702-20415754:+Tbio15.6386
tumor protein p53 binding protein 1ENSG00000067369TP53BP1chr15:43403061-43510728:-Tbio306.186
arginyl aminopeptidaseENSG00000176393RNPEPchr1:201982372-202006147:+Tchem111.65
glutamate ionotropic receptor NMDA type subunit 2AENSG00000183454GRIN2Achr16:9753404-10182754:-Tclin401.019
kelch like family member 8ENSG00000145332KLHL8chr4:87160103-87240314:-Tdark0.708333
transient receptor potential cation channel subfamily M member 1ENSG00000134160TRPM1chr15:31001061-31161273:-Tbio55.5687
potassium calcium-activated channel subfamily N member 1ENSG00000105642KCNN1chr19:17951293-18000080:+Tchem28.1954
matrix metallopeptidase 15ENSG00000102996MMP15chr16:58025566-58046901:+Tchem43.5105
PR/SET domain 2ENSG00000116731PRDM2chr1:13700198-13825079:+Tbio112.208
tubulin tyrosine ligaseENSG00000114999TTLchr2:112482154-112541739:+Tchem79.5
cytochrome P450 family 8 subfamily B member 1ENSG00000180432CYP8B1chr3:42856005-42876165:-Tbio20.5735
secretin receptorENSG00000080293SCTRchr2:119439843-119525301:-Tclin90.7837
uridine monophosphate synthetaseENSG00000114491UMPSchr3:124730366-124749273:+Tclin261.499
YOD1 deubiquitinaseENSG00000180667YOD1chr1:207043849-207052980:-Tbio7.05952
protein tyrosine phosphatase receptor type MENSG00000173482PTPRMchr18:7566782-8406861:+Tbio36.8738
protein kinase AMP-activated non-catalytic subunit gamma 2ENSG00000106617PRKAG2chr7:151556111-151877125:-Tbio74.2761
potassium voltage-gated channel subfamily A regulatory beta subunit 3ENSG00000170049KCNAB3chr17:7921859-7929803:-Tbio4.21944
inter-alpha-trypsin inhibitor heavy chain 4ENSG00000055955ITIH4chr3:52812975-52831479:-Tbio2562.36

 Showing page 154  		first page | previous page | next page | last page 








Contact us | | Terms & Conditions.
Copyright © 2020 University of Pennsylvania. All Rights Reserved.