PDGs

 

The “druggable genome”, a term coined by Hopkins and Groom in 2002(3), defines a subset of genes in the human genome encoding proteins that may be amenable to modulation by drug-like molecules. To define potentially druggable genes (PDGs) in the human genome, we integrated the PDG candidates generated by six independent studies in which the druggable genes were systematically annotated by different strategies at a whole genome level. .

List of the PDGs in the human genome


 Show   entries each page
 Jump to page  

 Total Page: 305 Total entries: 6083
  
 Showing page 146  first page | previous page | next page | last page 
 
HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationTDLPubTator Score
cannabinoid receptor 2ENSG00000188822CNR2chr1:23870526-23913362:-Tchem829.994
estrogen related receptor alphaENSG00000173153ESRRAchr11:64305572-64316743:+Tchem169.984
transient receptor potential cation channel subfamily V member 1ENSG00000196689TRPV1chr17:3565444-3597098:-Tclin1421.02
solute carrier organic anion transporter family member 4A1ENSG00000101187SLCO4A1chr20:62642445-62685785:+Tbio14.8686
potassium two pore domain channel subfamily K member 15ENSG00000124249KCNK15chr20:44745780-44752313:+Tbio25.9929
sclerostin domain containing 1ENSG00000171243SOSTDC1chr7:16461481-16530580:-Tbio17.0527
metastasis associated 1ENSG00000182979MTA1chr14:105419820-105470729:+Tbio197.736
phospholipase C delta 1ENSG00000187091PLCD1chr3:38007496-38029762:-Tchem116.619
polybromo 1ENSG00000163939PBRM1chr3:52545352-52685917:-Tchem402.769
complement C8 beta chainENSG00000021852C8Bchr1:56929210-56966140:-Tbio129.486
transglutaminase 1ENSG00000092295TGM1chr14:24249114-24264432:-Tchem522.6
MLLT10 histone lysine methyltransferase DOT1L cofactorENSG00000078403MLLT10chr10:21524675-21743630:+Tbio69.4187
kelch like family member 4ENSG00000102271KLHL4chrX:87517749-87670050:+Tdark2.94444
potassium calcium-activated channel subfamily N member 2ENSG00000080709KCNN2chr5:114360945-114496500:+Tchem62.4004
serpin family I member 1ENSG00000163536SERPINI1chr3:167735243-167825568:+Tbio109.329
latent transforming growth factor beta binding protein 3ENSG00000168056LTBP3chr11:65538560-65558930:-Tbio18.6116
interferon gamma receptor 1ENSG00000027697IFNGR1chr6:137197484-137219449:-Tbio171.4
dipeptidyl peptidase 9ENSG00000142002DPP9chr19:4675224-4724673:-Tchem44.8048
adhesion G protein-coupled receptor E2ENSG00000127507ADGRE2chr19:14732393-14778541:-Tbio38.1368
dehydrogenase/reductase 2ENSG00000100867DHRS2chr14:23630115-23645639:+Tbio63.8448

 Showing page 146  		first page | previous page | next page | last page 








Contact us | | Terms & Conditions.
Copyright © 2020 University of Pennsylvania. All Rights Reserved.