PDGs

 

The “druggable genome”, a term coined by Hopkins and Groom in 2002(3), defines a subset of genes in the human genome encoding proteins that may be amenable to modulation by drug-like molecules. To define potentially druggable genes (PDGs) in the human genome, we integrated the PDG candidates generated by six independent studies in which the druggable genes were systematically annotated by different strategies at a whole genome level. .

List of the PDGs in the human genome


 Show   entries each page
 Jump to page  

 Total Page: 305 Total entries: 6083
  
 Showing page 136  first page | previous page | next page | last page 
 
HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationTDLPubTator Score
transmembrane and immunoglobulin domain containing 2ENSG00000167664TMIGD2chr19:4292232-4302431:-Tbio2.75
CD93 moleculeENSG00000125810CD93chr20:23079349-23086340:-Tbio70.885
ATPase plasma membrane Ca2+ transporting 2ENSG00000157087ATP2B2chr3:10324023-10708031:-Tbio242.062
ATPase H+ transporting V1 subunit G1ENSG00000136888ATP6V1G1chr9:114587746-114598373:+Tbio2.07738
RNA guanylyltransferase and 5'-phosphataseENSG00000111880RNGTTchr6:88610272-88963721:-Tbio63.4082
homeodomain interacting protein kinase 2ENSG00000064393HIPK2chr7:139561570-139777778:-Tchem125.031
CD96 moleculeENSG00000153283CD96chr3:111292719-111665750:+Tbio21.8761
natriuretic peptide CENSG00000163273NPPCchr2:231921820-231926403:-Tbio348.346
lysophosphatidic acid receptor 2ENSG00000064547LPAR2chr19:19623668-19628930:-Tchem86.0628
sodium voltage-gated channel beta subunit 3ENSG00000166257SCN3Bchr11:123629187-123655244:-Tbio7.01545
chromobox 3ENSG00000122565CBX3chr7:26201162-26213356:+Tbio67.319
placenta enriched 1ENSG00000170965PLAC1chrX:134565838-134764322:-Tbio41.6282
NUAK family kinase 1ENSG00000074590NUAK1chr12:106063340-106140033:-Tchem31.9942
kallikrein related peptidase 11ENSG00000167757KLK11chr19:51022216-51028039:-Tbio109.933
inositol polyphosphate-5-phosphatase JENSG00000185133INPP5Jchr22:31122731-31134696:+Tbio31.5317
tudor domain containing 6ENSG00000180113TDRD6chr6:46687875-46704319:+Tdark4.40476
phosphatidylethanolamine binding protein 4ENSG00000134020PEBP4chr8:22713251-23000000:-Tbio27.4956
frizzled class receptor 10ENSG00000111432FZD10chr12:130162459-130165740:+Tbio16.5424
Rap guanine nucleotide exchange factor 4ENSG00000091428RAPGEF4chr2:172735274-173052893:+Tchem54.0877
SET and MYND domain containing 2ENSG00000143499SMYD2chr1:214281102-214337131:+Tchem30.3775

 Showing page 136  		first page | previous page | next page | last page 








Contact us | | Terms & Conditions.
Copyright © 2020 University of Pennsylvania. All Rights Reserved.