PDGs

 

The “druggable genome”, a term coined by Hopkins and Groom in 2002(3), defines a subset of genes in the human genome encoding proteins that may be amenable to modulation by drug-like molecules. To define potentially druggable genes (PDGs) in the human genome, we integrated the PDG candidates generated by six independent studies in which the druggable genes were systematically annotated by different strategies at a whole genome level. .

List of the PDGs in the human genome


 Show   entries each page
 Jump to page  

 Total Page: 305 Total entries: 6083
  
 Showing page 101  first page | previous page | next page | last page 
 
HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationTDLPubTator Score
gamma-glutamyltransferase light chain 1ENSG00000149435GGTLC1chr20:23985050-23988779:-Tdark2032.35
5-hydroxytryptamine receptor 1DENSG00000179546HTR1Dchr1:23191895-23194729:-Tclin184.959
ATPase Na+/K+ transporting subunit alpha 3ENSG00000105409ATP1A3chr19:41966582-41997497:-Tclin104.939
calmodulin 1ENSG00000198668CALM1chr14:90396502-90408261:+Tclin609.975
netrin G1ENSG00000162631NTNG1chr1:107140007-107483458:+Tbio23.3357
semaphorin 3EENSG00000170381SEMA3Echr7:83363906-83649010:-Tbio23.019
leukotriene B4 receptorENSG00000213903LTB4Rchr14:24311450-24318036:+Tchem170.618
lipase A, lysosomal acid typeENSG00000107798LIPAchr10:89213569-89414557:-Tchem409.419
EPH receptor B3ENSG00000182580EPHB3chr3:184561784-184582409:+Tchem39.1267
PAS domain containing serine/threonine kinaseENSG00000115687PASKchr2:241106099-241150264:-Tbio32.6365
leukocyte immunoglobulin like receptor B1ENSG00000104972LILRB1chr19:54617158-54700954:+Tbio233.75
integrin subunit alpha 10ENSG00000143127ITGA10chr1:145891208-145910189:-Tbio11.289
transient receptor potential cation channel subfamily M member 4ENSG00000130529TRPM4chr19:49157741-49211836:+Tchem108.735
eukaryotic translation initiation factor 2 alpha kinase 1ENSG00000086232EIF2AK1chr7:6022244-6059230:-Tchem69.99
NPC intracellular cholesterol transporter 1ENSG00000141458NPC1chr18:23506184-23586898:-Tbio497.518
relaxin 1ENSG00000107018RLN1chr9:5334969-5339873:-Tbio23.3748
colipaseENSG00000137392CLPSchr6:35794982-35797344:-Tbio175.697
gap junction protein beta 1ENSG00000169562GJB1chrX:71215194-71225516:+Tbio556.686
cyclin dependent kinase 8ENSG00000132964CDK8chr13:26254104-26405238:+Tchem72.9768
cyclin dependent kinase 16ENSG00000102225CDK16chrX:47217860-47229997:+Tchem21.2893

 Showing page 101  		first page | previous page | next page | last page 








Contact us | | Terms & Conditions.
Copyright © 2020 University of Pennsylvania. All Rights Reserved.