PDGs

 

The “druggable genome”, a term coined by Hopkins and Groom in 2002(3), defines a subset of genes in the human genome encoding proteins that may be amenable to modulation by drug-like molecules. To define potentially druggable genes (PDGs) in the human genome, we integrated the PDG candidates generated by six independent studies in which the druggable genes were systematically annotated by different strategies at a whole genome level. .

List of the PDGs in the human genome


 Show   entries each page
 Jump to page  

 Total Page: 305 Total entries: 6083
  
 Showing page 10  first page | previous page | next page | last page 
 
HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationTDLPubTator Score
RELA proto-oncogene, NF-kB subunitENSG00000173039RELAchr11:65653596-65663094:-Tchem2032.26
albuminENSG00000163631ALBchr4:73397114-73421412:+Tchem5011.65
egl-9 family hypoxia inducible factor 3ENSG00000129521EGLN3chr14:33924231-34462774:-Tchem88.4308
complement C2ENSG00000166278C2chr6:31897785-31945672:+Tbio34339.5
ubiquitin like with PHD and ring finger domains 1ENSG00000276043UHRF1chr19:4903080-4962154:+Tbio132.914
interleukin 6 signal transducerENSG00000134352IL6STchr5:55935095-55994993:-Tclin439.233
thyroglobulinENSG00000042832TGchr8:132866958-133134903:+Tbio2484.57
CD46 moleculeENSG00000117335CD46chr1:207752057-207795513:+Tbio1364.83
anti-Mullerian hormoneENSG00000104899AMHchr19:2249309-2252073:+Tbio1752.28
lysine methyltransferase 2CENSG00000055609KMT2Cchr7:152134922-152436005:-Tbio52.5469
transferrinENSG00000091513TFchr3:133745956-133779006:+Tbio11381.4
methylthioadenosine phosphorylaseENSG00000099810MTAPchr9:21802543-21937651:+Tchem187.745
matrix metallopeptidase 9ENSG00000100985MMP9chr20:46008908-46016561:+Tchem5939
signal transducer and activator of transcription 5AENSG00000126561STAT5Achr17:42287547-42311943:+Tchem988.134
ATM serine/threonine kinaseENSG00000149311ATMchr11:108222484-108369102:+Tchem1885.93
CD2 moleculeENSG00000116824CD2chr1:116754385-116769228:+Tclin2465.31
CD44 molecule (Indian blood group)ENSG00000026508CD44chr11:35138870-35232402:+Tbio3956.57
cyclin dependent kinase inhibitor 3ENSG00000100526CDKN3chr14:54396849-54420218:+Tbio432.995
integrin binding sialoproteinENSG00000029559IBSPchr4:87799581-87812435:+Tbio293.565
C-reactive proteinENSG00000132693CRPchr1:159712289-159714589:-Tbio27912.8

 Showing page 10  		first page | previous page | next page | last page 








Contact us | | Terms & Conditions.
Copyright © 2020 University of Pennsylvania. All Rights Reserved.