TCDA Expression

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Expression

Positive expression of a PDG in a given cancer type was defined as its mRNA expression was reliably detected in at least 50% of tumor specimens (i.e., the 50th percentile of fragments per kilobase of transcript per million mapped reads [FPKM] value ≥1).

Summary of PDG mRNA expression levels (FPKM value) in each cancer type

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HGNC	Ensembl	No. Detectable	ACC				BLCA				BRCA				CESC				CHOL				COAD				DLBC				ESCA				GBM				HNSC				KICH				KIRC				KIRP				LAML				LGG				LIHC				LUAD				LUSC				MESO				OV				PAAD				PCPG				PRAD				READ				SARC				SKCM				STAD				TGCT				THCA				THYM				UCEC				UCS				UVM
Symbol	Gene ID	Cancer Types	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th
SERPINE3	ENSG00000253309	0	0.02	0.04	0.08	0.22	0	0	0.02	0.04	0	0.01	0.03	0.08	0	0.01	0.02	0.05	0	0.03	0.04	0.12	0	0.01	0.03	0.08	0	0	0.02	0.03	0.01	0.03	0.08	0.15	0.01	0.04	0.09	0.14	0	0.01	0.02	0.05	0	0	0.01	0.02	0.01	0.03	0.07	0.12	0	0	0.02	0.07	0.03	0.06	0.12	0.2	0.03	0.06	0.1	0.19	0	0.01	0.03	0.06	0	0.01	0.02	0.05	0	0.01	0.03	0.07	0.01	0.03	0.26	1.77	0	0.02	0.05	0.1	0	0.02	0.04	0.09	0.02	0.04	0.1	0.17	0	0.01	0.03	0.07	0	0.01	0.02	0.06	0	0.02	0.04	0.1	0	0.02	0.05	0.11	0.01	0.03	0.07	0.14	0.02	0.06	0.1	0.21	0	0	0.01	0.03	0	0.02	0.04	0.09	0	0.01	0.03	0.09	0	0.02	0.06	0.16	0	0.03	0.26	0.6
CA7	ENSG00000168748	0	0.02	0.05	0.09	0.17	0	0.01	0.04	0.09	0	0.01	0.03	0.05	0	0.01	0.03	0.07	0	0	0	0.03	0.12	0.27	0.65	1.68	0	0	0.02	0.05	0	0.02	0.05	0.15	0.07	0.17	0.43	0.86	0	0.01	0.02	0.06	0.02	0.06	0.09	0.22	0	0	0.01	0.03	0	0	0.02	0.05	0	0.03	0.07	0.12	0.07	0.24	0.92	2.5	0	0	0.01	0.03	0	0.03	0.07	0.14	0	0.02	0.05	0.14	0.02	0.09	0.13	0.24	0.01	0.02	0.05	0.11	0.02	0.05	0.13	0.36	0	0.02	0.05	0.09	0.01	0.03	0.06	0.13	0.17	0.37	0.77	2.74	0	0	0.03	0.07	0	0.02	0.05	0.08	0.01	0.04	0.09	0.19	0.04	0.09	0.2	0.4	0.14	0.38	0.81	1.58	0	0.01	0.03	0.06	0	0.01	0.04	0.08	0.03	0.08	0.27	1.26	0	0.02	0.04	0.06
HTR5A	ENSG00000157219	0	0	0	0.01	0.08	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.01	0	0	0	0	0.02	0.07	0.32	0.56	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.06	0.24	0.86	2.59	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.01	0	0	0.01	0.51	0	0	0	0	0	0	0	0.01	0	0	0	0.01	0	0	0	0.01	0	0	0	0.02	0	0.03	0.07	0.17	0	0	0	0	0	0.01	0.34	1.22	0	0	0	0	0	0	0	0.1	0	0	0	0.01
DEFB116	ENSG00000215545	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
OR2T27	ENSG00000187701	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
P2RY4	ENSG00000186912	0	0	0	0.01	0.03	0	0.01	0.03	0.05	0.01	0.03	0.06	0.12	0	0.01	0.03	0.06	0	0.01	0.05	0.06	0.01	0.03	0.05	0.09	0	0	0.02	0.04	0.02	0.06	0.11	0.19	0	0.02	0.04	0.06	0	0.01	0.03	0.06	0.01	0.02	0.03	0.06	0.01	0.03	0.05	0.08	0	0.01	0.04	0.07	0.28	0.44	0.66	0.9	0.01	0.02	0.04	0.06	0	0	0.02	0.05	0.02	0.04	0.08	0.16	0.01	0.02	0.05	0.09	0	0.01	0.03	0.05	0	0.02	0.04	0.07	0.01	0.02	0.05	0.07	0	0.01	0.02	0.04	0.01	0.03	0.05	0.08	0.01	0.03	0.05	0.09	0	0.01	0.03	0.06	0	0.01	0.04	0.07	0.01	0.04	0.07	0.12	0.03	0.05	0.13	0.2	0.02	0.05	0.1	0.16	0	0.01	0.03	0.05	0	0	0.02	0.03	0	0	0.03	0.04	0	0	0.01	0.03
OR51F2	ENSG00000176925	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.01	0	0	0	0	0	0	0	0	0	0	0	0.02	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.02	0.05	0.11	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.02	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
TMPRSS12	ENSG00000186452	0	0	0	0	0.02	0	0.03	0.07	0.12	0	0	0.02	0.06	0	0.01	0.03	0.06	0	0	0.02	0.04	0	0	0	0	0	0	0	0.01	0	0.01	0.02	0.05	0	0	0	0.02	0	0	0.02	0.04	0	0.01	0.03	0.05	0	0	0.01	0.02	0	0	0.01	0.04	0	0.02	0.03	0.06	0	0	0	0.01	0	0	0	0.01	0	0	0.02	0.04	0	0	0.02	0.04	0	0	0.03	0.06	0.01	0.03	0.05	0.09	0	0	0.01	0.03	0	0	0.01	0.02	0	0	0.01	0.03	0	0	0	0	0	0	0	0.01	0	0	0	0.01	0	0	0.02	0.05	0	0	0.02	0.06	0	0.02	0.04	0.07	0	0.01	0.04	0.07	0	0	0.01	0.05	0	0	0.01	0.03	0	0	0	0
OR4N5	ENSG00000184394	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.02	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
OR56A5	ENSG00000188691	0	0	0	0	0	0	0	0	0.04	0	0	0	0.02	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.04	0.16	0	0	0	0	0	0	0	0.04	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.01	0	0	0.07	0.17	0	0	0	0	0	0	0.07	0.19	0	0	0	0	0	0	0	0	0	0	0	0.02	0	0	0	0.03	0	0	0	0	0	0	0	0.03	0	0	0.02	0.06	0	0	0	0.04	0	0	0	0	0	0	0	0.02	0	0	0	0.02	0	0	0	0.04	0	0	0	0
PRSS37	ENSG00000165076	0	0	0	0.01	0.03	0	0	0	0.02	0	0.01	0.02	0.04	0	0	0.01	0.03	0	0.01	0.03	0.06	0	0	0.03	0.05	0	0	0	0.02	0	0.01	0.02	0.05	0	0.01	0.03	0.06	0	0	0.01	0.02	0	0	0	0.01	0	0.02	0.05	0.09	0	0.02	0.04	0.07	0.04	0.09	0.18	0.33	0.01	0.03	0.07	0.1	0	0	0	0.01	0	0	0.02	0.04	0	0	0.02	0.04	0	0	0.02	0.04	0	0.02	0.04	0.09	0	0.01	0.03	0.06	0	0.01	0.03	0.06	0	0	0.02	0.03	0	0	0.02	0.04	0	0	0.02	0.03	0	0	0.01	0.03	0	0.01	0.03	0.06	0	0.01	0.03	0.05	0	0.02	0.05	0.09	0	0.02	0.06	0.15	0	0	0.01	0.04	0	0	0	0.02	0	0	0	0.01
OR2M5	ENSG00000162727	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.11	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
OR2J3	ENSG00000204701	0	0	0	0	0	0	0	0	0.04	0	0	0	0	0	0	0	0.02	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.02	0	0	0	0.02	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.01	0	0	0	0.02	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.02	0.05	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.03	0	0	0	0	0	0	0	0.03	0	0	0	0	0	0	0	0.03	0	0	0	0
BIRC8	ENSG00000163098	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.01	0	0	0	0	0	0	0	0.01	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.02	0	0	0	0.01	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
OVCH2	ENSG00000183378	0	0	0	0	0	0.03	0.15	0.56	1.26	0	0.02	0.12	0.36	0	0.01	0.08	0.45	0	0	0	0.01	0	0	0	0.01	0	0	0	0.01	0	0.01	0.06	0.2	0	0	0	0	0	0.01	0.04	0.19	0.03	0.13	0.33	1.71	0	0.01	0.05	0.27	0	0.01	0.08	0.42	0	0	0	0	0	0	0	0	0	0	0	0.01	0	0.03	0.11	0.28	0.01	0.05	0.18	0.43	0	0.01	0.12	0.47	0	0.02	0.08	0.33	0	0	0.03	0.1	0	0	0	0.01	0.01	0.04	0.15	0.33	0	0	0	0.01	0	0	0	0.08	0	0	0	0.01	0	0	0.01	0.06	0	0.02	0.06	0.25	0	0	0.01	0.03	0	0.01	0.06	0.22	0	0	0.05	0.13	0	0	0.03	0.18	0	0	0	0
OR7E24	ENSG00000237521	0	0	0	0	0	0	0	0.01	0.02	0	0	0	0.01	0	0	0	0.01	0	0	0	0.01	0	0	0	0	0	0	0	0.01	0	0	0	0.01	0	0	0	0	0	0	0	0.01	0	0	0	0	0	0	0	0.01	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.01	0	0	0	0.01	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.01	0	0	0	0.01	0	0	0	0.03	0.04	0.61	3.65	6.25	0	0	0	0.01	0	0	0	0	0	0	0.01	0.16	0	0	0	0.03	0	0	0	0
OR2G6	ENSG00000188558	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.04	0	0	0	0.01	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.04	0.11	0	0	0	0.04	0	0	0	0.04	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.07	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.03	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
OR1M1	ENSG00000170929	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.02	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.02	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.01	0.05	0.11	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.04	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.03	0	0	0	0	0	0	0	0
OR2G3	ENSG00000177476	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.02	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.13	0.36	0.81	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.07	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
OR10AG1	ENSG00000174970	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.01	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.03	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0

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